Rapid report
Mycobacterium tuberculosis infection is exacerbated in mice lacking lecithin:retinol acyltransferase

https://doi.org/10.1016/j.bbadis.2020.165909Get rights and content
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Highlights

  • Mice lacking LRAT show increased risk for an aggravated response to Mycobacterium tuberculosis (Mtb) infection.

  • Mtb infection is associated with increased levels of lung retinoids, but reductions in retinoid transcriptional signaling.

Keywords

Mycobacterium tuberculosis
Retinoids
Vitamin a deficiency

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