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A New Luminescent Zn(II) Complex: Selective Sensing of Cr2O72− and Prevention Activity Against Orthodontic Root Absorption by Suppressing Inflammatory Response

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Abstract

A novel luminescent coordination polymer (CP) based on Zn(II) ions as nodes [Zn(OPY)1.5(Hbtc)]n (1), [H3btc = trimesic acid and OPY = 4,4′-(oxybis(4,1-phenylene))dipyridine] has been prepared via the solvothermal assembly of a tripodal multicarboxylic acid ligand, a bis-pyridyl ligand with V-shape containing two diverse coordination patterns as well as Zn2 + ion. The experiments of photoluminescence also reflect that the coordination polymer 1 has high sensitivity to potassium dichromate, and its quenching efficiency is Ksv of 2.12 × 104 L·mol− 1. Furthermore, its treatment activity on orthodontic root absorption was evaluated in vivo. Firstly, the CCK-8 assay was performed in this research to evaluate the biotoxicity of the synthetic compound. Next, the TNF-α and Cbfα1 released by the periodontal ligament fibroblast was determined via the ELISA test kit. In addition to this, the signaling pathway of NF-κB activation after treated with compound was measured by the RT-PCR.

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Acknowledgements

The research was funded by Science and Technology Innovation Joint Fund Project of Fujian Science and Technology Department (2019Y9088).

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Correspondence to Wei-Hui Chen.

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Zhu, YF., Guan, WQ., Lin, F. et al. A New Luminescent Zn(II) Complex: Selective Sensing of Cr2O72− and Prevention Activity Against Orthodontic Root Absorption by Suppressing Inflammatory Response. J Fluoresc 30, 1233–1240 (2020). https://doi.org/10.1007/s10895-020-02597-w

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