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Parenting as a Mediator of Associations between Depression in Mothers and Children’s Functioning: A Systematic Review and Meta-Analysis

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A Correction to this article was published on 14 September 2020

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Abstract

This paper responds to the need to understand mechanisms in the pathways of risk from depression in mothers to their children’s functioning. We systematically reviewed evidence in support of one often-proposed mediational model: that problematic parenting at least partially explains associations between mothers’ depression and children’s adverse functioning. We further aimed to understand the conceptual and method-based moderators. Eligible studies had to be published in English in a peer-reviewed journal, include data on mothers’ depression and parenting and child functioning, and have a study design whereby measurement of depression in mothers preceded the measurement of parenting, which preceded the measurement of child outcome. Overall, across the 40 papers (37 “studies”) that met our inclusion criteria, we found a significant, albeit small effect (r = .016), for the mediational model as a whole. This effect size was robust to context (poverty and ethnicity), children’s characteristics of age and gender, and parenting quality (positive or negative). The model was significant for multiple domains of child functioning, although effect sizes varied across domains. We also found support, with small effect sizes, for all three pathways in the mediational model and some support for moderation of those pathways. Overall, the findings provide empirical support for parenting (both positive and negative) as a mediator of associations between mothers’ depression and a broad range of child functioning and suggest that interventions should target samples that represent the population in terms of poverty and ethnicity and children’s gender, with priority going to interventions targeting the youngest children.

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Change history

  • 14 September 2020

    The original version of the article requires a correction to one of the sentences. Under the section ‘Limitations’, the last sentence ‘Findings of no support for mediation was also deemed important as, for example, our findings suggest..’ should read as below. Also important were where we found no support for moderation of the mediation model; for example, our findings suggest that parenting as a mediator of associations between depression and child functioning is concerning regardless of the ages of the children, for both sons and daughters, and for a broad range of aspects of children’s functioning.

Notes

  1. First: DeRose et al. 2014 and Sterba et al. 2007; Second: Kam et al. 2011 and McCarty and McMahon 2003; Third: Morgan et al. 2014 and Shaw Group Study.

  2. For Maughan et al. (2007), Path A was negative, Path B negative, and Path C was positive after the correlation coefficients were transformed according to the above stated criteria. Therefore, conceptually, the indirect effect estimate represents higher depression to more positive parenting to more negative child outcome. Given that the indirect effect is the product of Path A and Path B, this calculation resulted in an indirect effect in the positive direction, thus failing to differentiate from studies in which the mediation is in the expected direction (i.e., higher depression to more negative parenting to more negative child outcome). Given that the relations in Maughan et al. were not significant, we conducted analyses both including and excluding this study and reported any discrepancies.

  3. Of note, when studies were excluded from analyses to address non-independence, social outcomes could no longer be included in analyses due to our a priori requirement that at least three studies be included in each level of categorical moderators. With social outcomes excluded from analyses, the strongest effect was for externalizing outcomes.

References

  • A. P. A. Publications and Communications Board Working Group on Journal Article Reporting Standards. (2008). Reporting standards for research in psychology: why do we need them? What might they be? American Psychologist, 63(9), 839–851. https://doi.org/10.1037/0003-066X.63.9.839.

    Article  Google Scholar 

  • Ahun, M. N., & Côté, S. M. (2018). Maternal depressive symptoms and early childhood cognitive development: a review of putative environmental mediators. Archives of Women's Mental Health, 22, 15–24.

    Google Scholar 

  • Ainsworth, M. D. S., Bell, S. M., & Stayton, D. J. (1974). Infant-mother attachment and social development: Socialisation as a product of recirpocal responsiveness to signals. In M. P. M. Richards (Ed.), The integration of a child into a social world (pp. 99–135). New York: Cambridnge University Press.

    Google Scholar 

  • Allen, A. M., Prince, C. B., & Dietz, P. M. (2009). Postpartum depressive symptoms and smoking relapse. American Journal of Preventive Medicine, 36(1), 9–12.

    PubMed  Google Scholar 

  • Allen, T., Oshri, A., Rogosch, F., Toth, S., & Cicchetti, D. (2019). Offspring personality mediates the association between maternal depression and childhood psychopathology. Journal of Abnormal Child Psychology, 47, 345–357. https://doi.org/10.1007/s10802-018-0453-3.

    Article  PubMed  PubMed Central  Google Scholar 

  • Ammerman, R. T., Altaye, M., Putnam, F. W., Teeters, A. R., Zou, Y., & Van Ginkel, J. B. (2015). Depression improvement and parenting in low-income mothers in home visiting. Archives of Women's Mental Health, 18(3), 555–563. https://doi.org/10.1007/s00737-014-0479-7.

    Article  PubMed  Google Scholar 

  • Atzil, S., Hendler, T., & Feldman, R. (2011). Specifying the neurobiological basis of human attachment: Brain, hormones, and behavior in synchronous and intrusive mothers. Neuropsychopharmacology, 36(13), 2603–2615. https://doi.org/10.1038/npp.2011.172.

    Article  PubMed  PubMed Central  Google Scholar 

  • Augustyn, M. B., Fulco, C. J., & Henry, K. L. (2018). Intergenerational continuity in depression: The importance of time-varying effects, maternal co-morbid health risk behaviors and child's gender. Journal of Youth and Adolescence. https://doi.org/10.1007/s10964-017-0805-2.

    Article  PubMed  PubMed Central  Google Scholar 

  • Avellar, S. A., & Supplee, L. H. (2013). Effectiveness of home visiting in improving child health and reducing child maltreatment. Pediatrics, 132(Supplement 2), S90–S99. https://doi.org/10.1542/peds.2013-1021G.

    Article  PubMed  Google Scholar 

  • Beck, C. T. (1999). Maternal depression and child behaviour problems: a meta-analysis. Journal of Advanced Nursing, 29(3), 623–629.

    PubMed  Google Scholar 

  • Belsky, J., & de Haan, M. (2011). Annual research review: Parenting and children’s brain development: the end of the beginning. Journal of Child Psychology and Psychiatry, 52(4), 409–428. https://doi.org/10.1111/j.1469-7610.2010.02281.x.

    Article  PubMed  Google Scholar 

  • Bigelow, A. E., Beebe, B., Power, M., Stafford, A.-L., Ewing, J., Egleson, A., et al. (2018). Longitudinal relations among maternal depressive symptoms, maternal mind-mindedness, and infant attachment behavior. Infant Behavior and Development, 51, 33–44.

    PubMed  Google Scholar 

  • Blazer, D. G., Kessler, R. C., McGonagle, K. A., & Swartz, M. S. (1994). The presence and distribution of major depression in a national community sample: The National Comorbidity Survey. American Journal of Psychiatry, 151, 979–986.

    PubMed  Google Scholar 

  • Bleker, L. S., van Dammen, L., Leeflang, M. M., Limpens, J., Roseboom, T. J., & de Rooij, S. R. (2018). Hypothalamic-pituitary-adrenal axis and autonomic nervous system reactivity in children prenatally exposed to maternal depression: A systematic review of prospective studies. Neuroscience & Biobehavioral Reviews. https://doi.org/10.1016/j.neubiorev.2018.05.033.

    Article  Google Scholar 

  • Bödeker, K., Fuchs, A., Führer, D., Kluczniok, D., Dittrich, K., Reichl, C., …, Resch, F. (2018). Impact of maternal early life maltreatment and maternal history of depression on child psychopathology: Mediating role of maternal sensitivity? Child Psychiatry & Human Development. https://doi.org/10.1007/s10578-018-0839-z

  • Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2009). Introduction to meta-analysis. Chichester: Wiley.

    Google Scholar 

  • Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2014). Comprehensive meta-analysis version 3. Englewood, NJ: Biostat.

    Google Scholar 

  • Borenstein, M., Higgins, J. P. T., Hedges, L. V., & Rothstein, H. R. (2017). Basics of meta-analysis: I2 is not an absolute measure of heterogeneity. Research Synthesis Methods, 8, 5–18.

    PubMed  Google Scholar 

  • Bornstein, M. H. (2006). Parenting science and practice, 6th Edn. In W. Damon, K. A. Renninger, & I. E. Sigel (Eds.), Handbook of child psychology (Vol. 4, pp. 893–949). Hoboken NJ: Wiley.

    Google Scholar 

  • Bornstein, M. H. (2012). Cultural Approaches to Parenting. Parenting, Science and Practice, 12(2–3), 212–221. https://doi.org/10.1080/15295192.2012.683359.

    Article  PubMed  PubMed Central  Google Scholar 

  • Burt, K. B., Van Dulmen, M. H. M., Carlivati, J., Egeland, B., Sroufe, L. A., Forman, D. R., …, Carlson, E. A. (2005). Mediating links between maternal depression and offspring psychopathology: the importance of independent data. Journal of Child Psychology and Psychiatry, 46, 490–499

  • Card, N. A. (2015). Applied meta-analysis for social science research. New York: Guilford Publications.

    Google Scholar 

  • Carter, A. S., Garrity-Rokous, F., Chazan-Cohen, R., Little, C., & Briggs-Gowan, M. J. (2001). Maternal depression and comorbitidy: Predicting early parenting, attachment security, and toddler social-emotional problems and competencies. Journal of the American Academy of Child and Adolescent Psychiatry, 40(1), 18–26.

    PubMed  Google Scholar 

  • Caughy, M. O., Huang, K.-Y., & Lima, J. (2009). Patterns of conflict interaction in mother–toddler dyads: Differences between depressed and non-depressed mothers. Journal of Child and Family Studies, 18(1), 10–20.

    Google Scholar 

  • Caughy, M. O., Mills, B., Owen, M. T., Dyer, N., & Oshri, A. (2017). Ethnic differences in mothering qualities and relations to academic achievement. Journal of Family Psychology, 31(7), 855–866. https://doi.org/10.1037/fam0000334.

    Article  PubMed  PubMed Central  Google Scholar 

  • Chen, M., Johnston, C., Sheeber, L., & Leve, C. (2009). Parent and adolescent depressive symptoms: The role of parental attributions. Journal of Abnormal Child Psychology, 37(1), 119–130.

    PubMed  PubMed Central  Google Scholar 

  • Cheung, M. W.-L. (2009). Comparison of methods for constructing confidence intervals of standardized indirect effects. Behavior Research Methods, 41(2), 425–438.

    PubMed  Google Scholar 

  • Cheung, M. W.-L. (2015). metaSEM: An R package for meta-analysis using structural equation modeling. Frontiers in Psychology. https://doi.org/10.3389/fpsyg.2014.01521.

    Article  PubMed  PubMed Central  Google Scholar 

  • Cicchetti, D., & Rogosch, F. A. (1996). Equifinality and multifinality in developmental psychopathology. Development & Psychopathology, 8, 597–600.

    Google Scholar 

  • Class, Q. A., Van Hulle, C. A., Rathouz, P. J., Applegate, B., Zald, D. H., & Lahey, B. B. (2019). Socioemotional dispositions of children and adolescents predict general and specific second-order factors of psychopathology in early adulthood: A 12-year prospective study. Journal of Abnormal Psychology, 128(6), 574–584. https://doi.org/10.1037/abn0000433.

    Article  PubMed  PubMed Central  Google Scholar 

  • Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Hillsdale, NJ: Erlbaum.

    Google Scholar 

  • Collins, W. A., Maccoby, E. E., Steinberg, L., Hetherington, E. M., & Bornstein, M. H. (2003). Contemporary research on parenting: The case for nature and nurture. Annual progress in child psychiatry and child development: 2000–2001 (pp. 125–153). Brunner-Routledge: New York.

    Google Scholar 

  • Compas, B. E., Forehand, R., Thigpen, J. C., Keller, G., Hardcastle, E. J., Cole, D. A., …, Colletti, C. (2011). Family group cognitive–behavioral preventive intervention for families of depressed parents: 18-and 24-month outcomes. Journal of Consulting and Clinical Psychology, 79(4), 488

  • Connell, A. M., & Goodman, S. H. (2002). The association between psychopathology in fathers versus mothers and children’s internalizing and externalizing behavior problems: A meta-analysis. Psychological Bulletin, 128, 746–773.

    PubMed  Google Scholar 

  • Cote, S. M., Ahun, M. N., Herba, C. M., Brendgen, M., Geoffroy, M. C., Orri, M., . . . Tremblay, R. E. (2018). Why is maternal depression related to adolescent internalizing problems? A 15-year population-based study. Journal of the American Academy of Child and Adolescent Psychiatry, 57(12), 916–924https://doi.org/10.1016/j.jaac.2018.04.024

  • Cox, J. (2017). Use and misuse of the edinburgh postnatal depression scale (EPDS): A ten point ‘survival analysis’. Archives Womens Mental Health, 20, 7890790.

    Google Scholar 

  • Criss, M. M., Shaw, D. S., Moilanen, K. L., Hitchings, J. E., & Ingoldsby, E. M. (2009). Family, neighborhood, and peer characteristics as predictors of child adjustment: A longitudinal analysis of additive and mediation models. Social Development, 18(3), 511–535.

    Google Scholar 

  • Dallaire, D. H., & Weinraub, M. (2005). The stability of parenting behaviors over the first 6 years of life. Early Childhood Research Quarterly, 20(2), 201–219.

    Google Scholar 

  • DeRose, L. M., Shiyko, M., Levey, S., Helm, J., & Hastings, P. D. (2014). Early maternal depression and social skills in adolescence: A marginal structural modeling approach. Social Development, 23(4), 753–769. https://doi.org/10.1111/sode.12073.

    Article  Google Scholar 

  • Diaz, A. P., Svob, C., Zhao, R., DiFabrizio, B., Warner, V., Gameroff, M. J., …, Wickramaratne, P. J. (2019). Adult outcomes of childhood disruptive disorders in offspring of depressed and healthy parents. Journal of Affective Disorders, 244, 107–112

  • Dickson, D. J., Huey, M., Laursen, B., Kiuru, N., & Nurmi, J.-E. (2018). Parent contributions to friendship stability during the primary school years. Journal of Family Psychology, 32(2), 217.

    PubMed  PubMed Central  Google Scholar 

  • Dietz, L. J., Jennings, K. D., Kelley, S. A., & Marshal, M. (2009). Maternal depression, paternal psychopathology, and toddlers' behavior problems. Journal of Clinical Child and Adolescent Psychology, 38(1), 48–61. https://doi.org/10.1080/15374410802575362.

    Article  PubMed  PubMed Central  Google Scholar 

  • Dittrich, K., Bermpohl, F., Kluczniok, D., Attar, C. H., Jaite, C., Fuchs, A., …, Winter, S. M. (2019). Alterations of empathy in mothers with a history of early life maltreatment, depression, and borderline personality disorder and their effects on child psychopathology. Psychological Medicine, 50, 1182

  • Dix, T., & Meunier, L. N. (2009). Depressive symptoms and parenting competence: An analysis of 13 regulatory processes. Developmental Review, 29(1), 45–68. https://doi.org/10.1016/j.dr.2008.11.002.

    Article  Google Scholar 

  • Dix, T., Gershoff, E. T., Meunier, L. N., & Miller, P. C. (2004). The affective structure of supportive parenting: depressive symptoms, immediate emotions, and child-oriented motivation. Developmental Psychology, 40(6), 1212.

    PubMed  Google Scholar 

  • Duan, C., Hare, M. M., Staring, M., & Deligiannidis, K. M. (2019). Examining the relationship between perinatal depression and neurodevelopment in infants and children through structural and functional neuroimaging research. International Review of Psychiatry, 31, 264–279.

    PubMed  Google Scholar 

  • Durbin, C., Klein, D. N., Hayden, E. P., Buckley, M. E., & Moerk, K. C. (2005). Temperamental emotionality in preschoolers and parental mood disorders. Journal of Abnormal Psychology, 114(1), 28–37.

    PubMed  Google Scholar 

  • Elgar, F. J., McGrath, P. J., Waschbusch, D. A., Stewart, S. H., & Curtis, L. J. (2004). Mutual influences on maternal depression and child adjustment problems. Clinical Psychology Review, 24(4), 441–459.

    PubMed  Google Scholar 

  • Ettekal, I., Eiden, R. D., Nickerson, A. B., Molnar, D. S., & Schuetze, P. (2019). Developmental cascades to children's conduct problems: The role of prenatal substance use, socioeconomic adversity, maternal depression and sensitivity, and children's conscience. Development and Psychopathology. https://doi.org/10.1017/S095457941800144X.

    Article  PubMed Central  Google Scholar 

  • Fang, G., Yu, H., Zhi, S., Xi, M., Peng, Z.-W., Cai, M., …, Wang, Y. (2019). Sex differences in intergenerational transfer risk of major depressive disorder. Medical Science Monitor, 25, 9887–9892https://doi.org/10.12659/MSM.917888

  • Feurer, C., Hammen, C. L., & Gibb, B. E. (2014). Chronic and episodic stress in children of depressed mothers. Journal of Clinical Child & Adolescent Psychology, 45, 270–278. https://doi.org/10.1080/15374416.2014.963859.

    Article  Google Scholar 

  • Finlon, K. J., Izard, C. E., Seidenfeld, A., Johnson, S. R., Cavadel, E. W., Ewing, E. S. K., et al. (2015). Emotion-based preventive intervention: Effectively promoting emotion knowledge and adaptive behavior among at-risk preschoolers. Development and Psychopathology, 27(4pt1), 1353–1365. https://doi.org/10.1017/S0954579414001461.

    Article  PubMed  PubMed Central  Google Scholar 

  • Frye, A., & Garber, J. (2005). The relations among maternal depression, maternal criticism, and adolescents' externalizing and internalizing symptoms. Journal of Abnormal Child Psychology, 33, 1–11.

    PubMed  Google Scholar 

  • Garber, J., & Flynn, C. (2001). Predictors of depressive cognitions in young adolescents. Cognitive Therapy and Research, 25(4), 353–376.

    Google Scholar 

  • Gjerde, L. C., Eilertsen, E. M., Hannigan, L. J., Eley, T., Røysamb, E., Reichborn-Kjennerud, T., …, Ystrom, E. (2019). Associations between maternal depressive symptoms and risk for offspring early-life psychopathology: the role of genetic and non-genetic mechanisms. Psychological Medicinehttps://doi.org/10.1017/S0033291719003301

  • Goodman, S. H. (2020). Intergenerational transmission of depression. Annual Review of Clinical Psychology. https://doi.org/10.1146/annurev-clinpsy-071519-113915.

    Article  PubMed  Google Scholar 

  • Goodman, S. H., & Garber, J. (2017). Evidence-based interventions for depressed mothers and their young children. Child Development, 88(2), 368–377. https://doi.org/10.1111/cdev.12732.

    Article  PubMed  PubMed Central  Google Scholar 

  • Goodman, S. H., & Gotlib, I. H. (1999). Risk for psychopathology in the children of depressed mothers: A developmental model for understanding mechanisms of transmission. Psychological Review, 106, 458–490.

    PubMed  Google Scholar 

  • Goodman, S. H., Rouse, M. H., Connell, A., Broth, M., Hall, C., & Heyward, D. (2011). Maternal depression and child psychopathology: A meta-analytic review. Clinical Child and Family Psychology Review, 14, 1–27. https://doi.org/10.1007/s10567-010-0080-1.

    Article  PubMed  Google Scholar 

  • Gruhn, M. A., Dunbar, J. P., Watson, K. H., Reising, M. M., McKee, L., Forehand, R., …, Compas, B. E. (2016). Testing specificity among parents’ depressive symptoms, parenting, and child internalizing and externalizing symptoms. Journal of Family Psychology, 30, 309–319https://doi.org/10.1037/fam0000183

  • Gueron-Sela, N., Camerota, M., Willoughby, M. T., Vernon-Feagans, L., & Cox, M. J. (2017). Maternal depressive symptoms, mother-child interactions, and children’s executive function. Developmental Psychology. https://doi.org/10.1037/dev0000389.supp.

    Article  PubMed  PubMed Central  Google Scholar 

  • Guo, N., Robakis, T., Miller, C., & Butwick, A. (2018). Prevalence of depression among women of reproductive age in the United States. Obstetrics and Gynecology, 131(4), 671–679.

    PubMed  PubMed Central  Google Scholar 

  • Hails, K. A., Shaw, D. S., Leve, L. D., Ganiban, J. M., Reiss, D., Natsuaki, M. N., et al. (2018). Interaction between adoptive mothers’ and fathers’ depressive symptoms in risk for children’s emerging problem behavior. Social Development. https://doi.org/10.1111/sode.12352.

    Article  PubMed  Google Scholar 

  • Hammen, C. (2002). Context of stress in families of children with depressed parents. In S. H. Goodman & I. H. Gotlib (Eds.), Children of depressed parents: Mechanisms of risk and implications for treatment (pp. 175–202). Washington: American Psychological Association.

    Google Scholar 

  • Hankin, B. L., Mermelstein, R., & Roesch, L. (2007). Sex differences in adolescent depression: stress exposure and reactivity models. Child Development, 78(1), 279–295.

    PubMed  Google Scholar 

  • Hannigan, L. J., Eilertsen, E. M., Gjerde, L. C., Reichborn-Kjennerud, T., Eley, T. C., Rijsdijk, F. V., …, McAdams, T. A. (2018). Maternal prenatal depressive symptoms and risk for early-life psychopathology in offspring: Genetic analyses in the Norwegian Mother and Child Birth Cohort Study. The Lancet Psychiatry, 5(10), 808–815https://doi.org/10.1016/S2215-0366(18)30225-6

  • Hayden, E. P., Olino, T. M., Mackrell, S. V., Jordan, P. L., Desjardins, J., & Katsiroumbas, P. (2013). Cognitive vulnerability to depression during middle childhood: Stability and associations with maternal affective styles and parental depression. Personality and Individual Differences, 55(8), 892–897.

    PubMed  PubMed Central  Google Scholar 

  • Hemmeter, M. L., Snyder, P., & Fox, L. (2018). Using the teaching pyramid observation tool (TPOT) to support implementation of social-emotional teaching practices. School Mental Health, 10(3), 202–213. https://doi.org/10.1007/s12310-017-9239-y.

    Article  Google Scholar 

  • Henry, L. M., Forehand, R., Watson, K. H., Gruhn, M., Bettis, A. H., McKee, L. G., et al. (2018). Parental depressive symptoms and parenting: Associations with children’s coping in families of depressed parents. Parenting, 18(4), 278–293.

    Google Scholar 

  • Hoffman, C., Crnic, K. A., & Baker, J. K. (2006). Maternal depression and parenting: Implications for children's emergent emotion regulation and behavioral functioning. Parenting-Science and Practice, 6(4), 271–295.

    Google Scholar 

  • Hofmann, S. G., & Hayes, S. C. (2018). The future of intervention science: Process-based therapy. Clinical Psychological Science. https://doi.org/10.1177/2167702618772296.

    Article  PubMed  PubMed Central  Google Scholar 

  • Hops, H. (1992). Parental depression and child behaviour problems: Implications for behavioural family intervention. Behaviour Change, 9, 126–138.

    Google Scholar 

  • Jaser, S. S., Langrock, A. M., Keller, G., Merchant, M. J., Benson, M. A., Reeslund, K., …, Compas, B. E. (2005). Coping with the stress of parental depression II: Adolescent and parent reports of coping and adjustment. Journal of Clinical Child and Adolescent Psychology, 34(1), 193–205

  • Jones, D. J., Forehand, R., & Neary, E. M. (2001). Family transmission of depressive symptoms: Replication across Caucasian and African American mother-child dyads. Behavior Therapy, 32(1), 123–138.

    Google Scholar 

  • Kam, C.-M., Greenberg, M., Bierman, K., Coie, J., Dodge, K., Foster, M., …, Pinderhughes, E. (2011). Maternal depressive symptoms and child social preference during the early school years: mediation by maternal warmth and child emotion regulation. Journal of Abnormal Child Psychology, 39(3), 365–377https://doi.org/10.1007/s10802-010-9468-0

  • Karreman, A., Van Tuijl, C., van Aken, M. A., & Deković, M. (2006). Parenting and self-regulation in preschoolers: A meta-analysis. Infant and Child Development: An International Journal of Research and Practice, 15(6), 561–579.

    Google Scholar 

  • Kawabata, Y., Alink, L. R. A., Tseng, W.-L., van Ijzendoorn, M. H., & Crick, N. R. (2011). Maternal and paternal parenting styles associated with relational aggression in children and adolescents: A conceptual analysis and meta-analytic review. Developmental Review, 31(4), 240–278. https://doi.org/10.1016/j.dr.2011.08.001.

    Article  Google Scholar 

  • Keenan-Miller, D., Hammen, C., & Brennan, P. A. (2010). Mediators of aggression among young adult offspring of depressed mothers. Journal of Abnormal Psychology, 119(4), 836.

    PubMed  PubMed Central  Google Scholar 

  • Kendler, K. S., Gardner, C. O., Neale, M. C., & Prescott, C. A. (2001). Genetic risk factors for major depression in men and women: Similar or different heritabilities and same or partly distinct genes? Psychological Medicine, 31(4), 605–616.

    PubMed  Google Scholar 

  • Kenny, D. A. (2018). Mediation. Retrieved 2019, from https://davidakenny.net/cm/mediate.htm

  • Kuckertz, J. M., Mitchell, C., & Wiggins, J. L. (2018). Parenting mediates the impact of maternal depression on child internalizing symptoms. Depression and Anxiety, 35(1), 89–97.

    PubMed  Google Scholar 

  • La Placa, V., & Corlyon, J. (2016). Unpacking the relationship between parenting and poverty: Theory, evidence and policy. Social Policy and Society, 15(1), 11–28.

    Google Scholar 

  • Larzelere, R. E., Gunnoe, M. L., & Ferguson, C. J. (2018). Improving causal inferences in meta-analyses of longitudinal studies: Spanking as an illustration. Child Development, 89(6), 2038–2050. https://doi.org/10.1111/cdev.13097.

    Article  PubMed  Google Scholar 

  • Lawler, J. M., Bocknek, E. L., McGinnis, E. W., Martinez-Torteya, C., Rosenblum, K. L., & Muzik, M. (2018). Maternal postpartum depression increases vulnerability for toddler behavior problems through infant cortisol reactivity. Infancy. https://doi.org/10.1111/infa.12271.

    Article  PubMed  Google Scholar 

  • Leadbeater, B. J., Bishop, S. J., & Raver, C. (1996). Quality of mother-toddler interactions, maternal depressive symptoms, and behavior problems in preschoolers of adolescent mothers. Developmental Psychology, 32(2), 280–288.

    Google Scholar 

  • Lester, B. M., Conradt, E., LaGasse, L. L., Tronick, E. Z., Padbury, J. F., & Marsit, C. J. (2018). Epigenetic programming by maternal behavior in the human infant. Pediatrics, 142(4), 1–8. https://doi.org/10.1542/peds.2017-1890.

    Article  Google Scholar 

  • Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gotzsche, P. C., & Ioannidis, J. P. A. (2009). The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: Explanation and elaboration. BMJ. https://doi.org/10.1136/bmj.b2700.

    Article  PubMed  PubMed Central  Google Scholar 

  • Lipsey, M. W., & Wilson, D. B. (2001). Practical meta-analysis. Thousand Oaks: Sage Publications, Inc.

    Google Scholar 

  • Lovejoy, M. C., Graczyk, P. A., O'Hare, E., & Neuman, G. (2000). Maternal depression and parenting behavior: A meta-analytic review. Clinical Psychology Review, 20(5), 561–592.

    PubMed  Google Scholar 

  • Lovibond, P. F. (1998). Long-term stability of depression, anxiety, and stress syndromes. Journal of Abnormal Psychology, 107(3), 520.

    PubMed  Google Scholar 

  • Madigan, S., Wade, M., Plamondon, A., & Jenkins, J. (2015). Maternal abuse history, postpartum depression, and parenting: Links with preschoolers’internalizing problems. Infant Mental Health Journal, 36(2), 146–155.

    PubMed  Google Scholar 

  • Malm, E. K., & Henrich, C. C. (2019). Longitudinal relationships between parent factors, children’s bullying, and victimization behaviors. Child Psychiatry & Human Development, 50(5), 789–802.

    Google Scholar 

  • Masarik, A. S., & Conger, R. D. (2017). Stress and child development: a review of the Family Stress Model. Current Opinion in Psychology, 13, 85–90. https://doi.org/10.1016/j.copsyc.2016.05.008.

    Article  PubMed  Google Scholar 

  • Mason, W. A., Chmelka, M. B., Trudeau, L., & Spoth, R. L. (2017). Gender moderation of the intergenerational transmission and stability of depressive symptoms from early adolescence to early adulthood. Journal of Youth and Adolescence. https://doi.org/10.1007/s10964-016-0480-8.

    Article  PubMed  Google Scholar 

  • Maughan, A., Cicchetti, D., Toth, S., & Rogosch, F. (2007). Early-occurring maternal depression and maternal negativity in predicting young children’s emotion regulation and socioemotional difficulties. Journal of Abnormal Child Psychology, 35(5), 685–703. https://doi.org/10.1007/s10802-007-9129-0.

    Article  PubMed  Google Scholar 

  • Maxwell, S. E., Cole, D. A., & Mitchell, M. A. (2011). Bias in cross-sectional analyses of longitudinal mediation: Partial and complete mediation under an autoregressive model. Multivariate Behavioral Research, 46(5), 816–841.

    PubMed  Google Scholar 

  • McCarty, C. A., & McMahon, R. J. (2003). Mediators of the relation between maternal depressive symptoms and child internalizing and disruptive behavior disorders. Journal of Family Psychology, 17(4), 545.

    PubMed  PubMed Central  Google Scholar 

  • McLeod, B. D., Weisz, J. R., & Wood, J. J. (2007a). Examining the association between parenting and childhood depression: A meta-analysis. Clinical Psychology Review, 27(8), 986–1003.

    PubMed  Google Scholar 

  • McLeod, B. D., Wood, J. J., & Weisz, J. R. (2007b). Examining the association between parenting and childhood anxiety: A meta-analysis. Clinical Psychology Review, 27(2), 155–172.

    PubMed  Google Scholar 

  • McManus, B. M., & Poehlmann, J. (2012). Parent–child interaction, maternal depressive symptoms and preterm infant cognitive function. Infant Behavior and Development, 35(3), 489–498.

    PubMed  Google Scholar 

  • Mills-Koonce, W. R., Willoughby, M. T., Zvara, B., Barnett, M., Gustafsson, H., & Cox, M. J. (2015). Mothers' and fathers' sensitivity and children's cognitive development in low-income, rural families. Journal of Applied Developmental Psychology, 38, 1–10. https://doi.org/10.1016/j.appdev.2015.01.001.

    Article  PubMed  PubMed Central  Google Scholar 

  • Morgan, J. K., Shaw, D. S., & Forbes, E. E. (2014). Maternal depression and warmth during childhood predict age 20 neural response to reward. Journal of the American Academy of Child & Adolescent Psychiatry, 53(1), 108–117.

    Google Scholar 

  • Murray, L., Arteche, A., Fearon, P., Halligan, S., Goodyer, I., & Cooper, P. (2011). Maternal postnatal depression and the development of depression in offspring up to 16 years of age. Journal of the American Academy of Child & Adolescent Psychiatry, 50(5), 460–470.

    Google Scholar 

  • Murray, L., Halligan, S. L., Goodyer, I., & Herbert, J. (2010). Disturbances in early parenting of depressed mothers and cortisol secretion in offspring: a preliminary study. Journal of affective disorders, 122(3), 218–223.

    PubMed  Google Scholar 

  • National Research Council. (2000). From neurons to neighborhoods: The science of early childhood development. Washington: National Academies Press.

    Google Scholar 

  • Natsuaki, M. N., Shaw, D. S., Neiderhiser, J. M., Ganiban, J. M., Harold, G. T., Reiss, D., et al. (2014). Raised by depressed parents: is it an environmental risk? Clinical Child and Family Psychology Review, 17, 357–367. https://doi.org/10.1007/s10567-014-0169-z.

    Article  PubMed  PubMed Central  Google Scholar 

  • Neuenschwander, R., Hookenson, K., Brain, U., Grunau, R. E., Devlin, A. M., Weinberg, J., …, Oberlander, T. F. (2018). Children's stress regulation mediates the association between prenatal maternal mood and child executive functions for boys, but not girls. Development and Psychopathology, 30(3), 953–969https://doi.org/10.1017/S095457941800041X

  • Neuhauser, A., Ramseier, E., Schaub, S., Burkhardt, S. C., & Lanfranchi, A. (2018). Mediating role of maternal sensitivity: Enhancing language development in at-risk families. Infant Mental Health Journal, 39(5), 522–536.

    PubMed  Google Scholar 

  • Ng-Knight, T., Shelton, K. H., Frederickson, N., McManus, I., & Rice, F. (2018). Maternal depressive symptoms and adolescent academic attainment: Testing pathways via parenting and self-control. Journal of Adolescence, 62, 61–69.

    PubMed  Google Scholar 

  • O'Connor, T. G., Miller, R. K., & Salafia, C. M. (2019). Placental studies for child development. Child Development Perspectives. https://doi.org/10.1111/cdep.12338.

    Article  PubMed  PubMed Central  Google Scholar 

  • Ohlsson, H., & Kendler, K. S. (2019). Applying causal inference methods in psychiatric epidemiology: A review. JAMA Psychiatry. https://doi.org/10.1001/jamapsychiatry.2019.3758.

    Article  Google Scholar 

  • Orri, M., Girard, L.-C., Pingault, J.-B., Rouquette, A., Herba, C., Falissard, B., …, Phd, S. (2018). Harsh parenting practices mediate the association between parent affective profiles and child adjustment outcomes: Differential associations for mothers and fathers. International Journal of Behavioral Development. https://doi.org/10.1177/0165025418769376

  • Parkes, A., Green, M., & Mitchell, K. (2018). Coparenting and parenting pathways from the couple relationship to children’s behavior problems. Journal of Family Psychology. https://doi.org/10.1037/fam0000492.

    Article  PubMed  PubMed Central  Google Scholar 

  • Pastorelli, C., Lansford, J. E., Luengo Kanacri, B. P., Malone, P. S., Di Giunta, L., Bacchini, D., …, Bornstein, M. H. (2015). Positive parenting and children's prosocial behavior in eight countries. Journal of Child Psychology and Psychiatry, 57(7), 824–834

  • Paulsell, D., Grosso, P. D., & Supplee, L. (2014). Supporting Replication And Scale-Up Of Evidence-Based Home Visiting Programs: Assessing the implementation knowledge base. American Journal of Public Health, 104(9), 1624–1632. https://doi.org/10.2105/ajph.2014.301962.

    Article  PubMed  PubMed Central  Google Scholar 

  • Paulussen-Hoogeboom, M. C., Stams, G. J. J., Hermanns, J., & Peetsma, T. T. (2007). Child negative emotionality and parenting from infancy to preschool: A meta-analytic review. Developmental Psychology, 43(2), 438.

    PubMed  Google Scholar 

  • Pinquart, M. (2017). Associations of parenting dimensions and styles with externalizing problems of children and adolescents: An updated meta-analysis. Developmental Psychology, 53(5), 873.

    PubMed  Google Scholar 

  • Podsakoff, P. M., MacKenzie, S. B., Lee, J.-Y., & Podsakoff, N. P. (2003). Common method biases in behavioral research: A critical review of the literature and recommended remedies. Journal of applied psychology, 88(5), 879.

    PubMed  Google Scholar 

  • Pratt, M., Zeev-Wolf, M., Goldstein, A., & Feldman, R. (2019). Exposure to early and persistent maternal depression impairs the neural basis of attachment in preadolescence. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 93, 21–30. https://doi.org/10.1016/j.pnpbp.2019.03.005.

    Article  PubMed  Google Scholar 

  • Psychogiou, L., Russell, G., & Owens, M. (2019). Parents’ postnatal depressive symptoms and their children's academic attainment at 16 years: Pathways of risk transmission. British Journal of Psychology. https://doi.org/10.1111/bjop.12378.

    Article  PubMed  Google Scholar 

  • R Core Team. (2017). R: a language and environment for statistical computing. Vienna: R Foundation for Statistical Computing.

    Google Scholar 

  • Raine, K. H., Cockshaw, W., Boyce, P., & Thorpe, K. (2019). Prenatal maternal personality as an early predictor of vulnerable parenting style. Archives of Women's Mental Health, 22, 799.

    Google Scholar 

  • River, L. M., Borelli, J. L., Vazquez, L. C., & Smiley, P. A. (2018). Learning helplessness in the family: Maternal agency and the intergenerational transmission of depressive symptoms. Journal of Family Psychology. https://doi.org/10.1037/fam0000479.

    Article  PubMed  Google Scholar 

  • Rosenthal, M. L. C. (1994). The fugitive literature. In H. Cooper & L. V. Hedges (Eds.), The handbook of research synthesis (pp. 85–94). New York: Russell Sage Foundation.

    Google Scholar 

  • Rothbaum, F., & Weisz, J. R. (1994). Parental caregiving and child externalizing behavior in nonclinical samples: A meta-analysis. Psychological Bulletin, 116(1), 55.

    PubMed  Google Scholar 

  • Sanders, M. R., Bor, W., & Morawska, A. (2007). Maintenance of treatment gains: A comparison of enhanced, standard, and self-directed triple p-positive parenting program. Journal of Abnormal Child Psychology, 35(6), 983–998. https://doi.org/10.1007/s10802-007-9148-x.

    Article  PubMed  Google Scholar 

  • Sandler, I. N., Ayers, T. S., Wolchik, S. A., Tein, J.-Y., Kwok, O.-M., Haine, R. A., …, Padgett-Jones, S. (2003). The family bereavement program: efficacy evaluation of a theory-based prevention program for parentally bereaved children and adolescents. Journal of Consulting and Clinical Psychology, 71(3), 587

  • Schleider, J. L., Patel, A., Krumholz, L., Chorpita, B. F., & Weisz, J. R. (2014). Relation between parent symptomatology and youth problems: Multiple mediation through family income and parent-youth stress. Child Psychiatry & Human Development. https://doi.org/10.1007/s10578-014-0446-6.

    Article  Google Scholar 

  • Schuetze, P., Zhao, J., Eiden, R., Shisler, S., & Huestis, M. (2019). Prenatal exposure to tobacco and marijuana and child autonomic regulation and reactivity: An analysis of indirect pathways via maternal psychopathology and parenting. Developmental Psychobiology. https://doi.org/10.1002/dev.21844.

    Article  PubMed  Google Scholar 

  • Sellers, R., Harold, G. T., Elam, K., Rhoades, K. A., Potter, R., Mars, B., …, Collishaw, S. (2014). Maternal depression and co-occurring antisocial behaviour: Testing maternal hostility and warmth as mediators of risk for offspring psychopathology. Journal of Child Psychology and Psychiatry, 55, 112–120https://doi.org/10.1111/jcpp.12111

  • Shaw, D. S., Gilliom, M., Ingoldsby, E. M., & Nagin, D. S. (2003). Trajectories leading to school-age conduct problems. Developmental Psychology, 39(2), 189.

    PubMed  Google Scholar 

  • Shaw, D. S., Hyde, L. W., & Brennan, L. M. (2012). Early predictors of boys' antisocial trajectories. Development and Psychopathology, 24(3), 871–888.

    PubMed  PubMed Central  Google Scholar 

  • Shaw, D. S., Lacourse, E., & Nagin, D. S. (2005). Developmental trajectories of conduct problems and hyperactivity from ages 2 to 10. Journal of Child Psychology and Psychiatry, 46(9), 931–942.

    PubMed  Google Scholar 

  • Sheeber, L., Davis, B., & Hops, H. (2002). Gender-specific vulnerability to depression in children of depressed mothers. In S. H. Goodman & I. H. Gotlib (Eds.), Children of depressed parents: Mechanisms of risk and implications for treatment (pp. 253–274). Washington: American Psychological Association.

    Google Scholar 

  • Shelleby, E. C., & Ogg, J. (2019). Longitudinal relationships between parent involvement, parental warmth, ADHD symptoms, and reading achievement. Journal of Attention Disorders, 24, 737.

    PubMed  Google Scholar 

  • Slagt, M., Dubas, J. S., Deković, M., & van Aken, M. A. (2016). Differences in sensitivity to parenting depending on child temperament: A meta-analysis. Psychological Bulletin, 142(10), 1068.

    PubMed  Google Scholar 

  • Snyder, J. (1991). Discipline as a mediator of the impact of maternal stress and mood on child conduct problems. Development & Psychopathology, 3, 263–276.

    Google Scholar 

  • Spieker, S. J., Oxford, M. L., Fleming, C. B., & Lohr, M. J. (2018). Parental childhood adversity, depressive symptoms, and parenting quality: effects on toddler self-regulation in child welfare services involved families. Infant Mental Health Journal, 39(1), 5–16.

    PubMed  Google Scholar 

  • Stein, A., Malmberg, L. E., Sylva, K., Barnes, J., & Leach, P. (2008). The influence of maternal depression caregiving and socioeconomic status in the post-natal year on children's language development. Child Care Health and Development, 34(5), 603–612.

    Google Scholar 

  • Sterba, S. K., Prinstein, M. J., & Cox, M. J. (2007). Trajectories of internalizing problems across childhood: Heterogeneity, external validity, and gender differences. Development and Psychopathology, 19(2), 345–366.

    PubMed  Google Scholar 

  • Sullivan, P. F., Neale, M. C., & Kendler, K. S. (2000). Genetic epidemiology of major depression: Review and meta-analysis. American Journal of Psychiatry, 157, 1552–1562.

    PubMed  Google Scholar 

  • Taraban, L., Shaw, D. S., Leve, L. D., Natsuaki, M. N., Ganiban, J. M., Reiss, D., et al. (2018). Parental depression, overreactive parenting, and early childhood externalizing problems: moderation by social support. Child Development. https://doi.org/10.1111/cdev.13027.

    Article  PubMed  PubMed Central  Google Scholar 

  • Tryon, W. W. (2018). Mediators and Mechanisms. Clinical Psychological Science, 6, 619–628. https://doi.org/10.1177/2167702618765791.

    Article  Google Scholar 

  • Ulmer-Yaniv, A., Djalovski, A., Priel, A., Zagoory-Sharon, O., & Feldman, R. (2018). Maternal depression alters stress and immune biomarkers in mother and child. Depression and Anxiety. https://doi.org/10.1002/da.22818.

    Article  PubMed  Google Scholar 

  • Valente, M. J., Pelham, W. E., III, Smyth, H., & MacKinnon, D. P. (2017). Confounding in statistical mediation analysis: What it is and how to address it. Journal of Counseling Psychology, 64(6), 659.

    PubMed  PubMed Central  Google Scholar 

  • Villodas, M. T., Bagner, D. M., & Thompson, R. (2018). A step beyond maternal depression and child behavior problems: The role of mother–child aggression. Journal of Clinical Child & Adolescent Psychology, 47(4), 634–641.

    Google Scholar 

  • Webster-Stratton, C., Reid, M. J., & Hammond, M. (2004). Treating children with early-onset conduct problems: Intervention outcomes for parent, child, and teacher training. Journal of Clinical Child and Adolescent Psychology, 33(1), 105–124.

    PubMed  Google Scholar 

  • Weissman, M. M., Bland, R. C., Canino, G. J., Faravelli, C., Greenwald, S., Hwu, H.-G., …, Yeh, E.-K. (1996). Cross-national epidemiology of major depression and bipolar disorder. JAMA, 276(4), 293–299https://doi.org/10.1001/jama.1996.03540040037030

  • Willoughby, M. T., Mills-Koonce, R., Propper, C. B., & Waschbusch, D. A. (2013). Observed parenting behaviors interact with a polymorphism of the brain-derived neurotrophic factor gene to predict the emergence of oppositional defiant and callous–unemotional behaviors at age 3 years. Development and Psychopathology, 25(41), 903–917.

    PubMed  Google Scholar 

  • Withers, M. C., Cooper, A., Rayburn, A. D., & McWey, L. M. (2016). Parent-adolescent relationship quality as a link in adolescent and maternal depression. Children and Youth Services Review, 70, 309–314.

    Google Scholar 

  • Wolchik, S. A., Sandler, I. N., Millsap, R. E., Plummer, B. A., Greene, S. M., Anderson, E. R., …, Haine, R. A. (2002). Six-year follow-up of preventive interventions for children of divorce: A randomized controlled trial. JAMA, 288(15), 1874–1881

  • Wu, V., East, P., Delker, E., Blanco, E., Caballero, G., Delva, J., …, Gahagan, S. (2018). Associations among mothers’ depression, emotional and learning‐material support to their child, and children's cognitive functioning: A 16‐year longitudinal study. Child development 90, 1952

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Acknowledgements

Emily Bartholomay provided valuable assistance with the initial steps in this review. The authors also gratefully acknowledge assistance from Katherine Cullum, Meeka Maier, Yuk Fai Cheong.

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Goodman, S.H., Simon, H.F.M., Shamblaw, A.L. et al. Parenting as a Mediator of Associations between Depression in Mothers and Children’s Functioning: A Systematic Review and Meta-Analysis. Clin Child Fam Psychol Rev 23, 427–460 (2020). https://doi.org/10.1007/s10567-020-00322-4

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