Editorial overview: From powerful tools to useful products: protein engineering after 35 years of directed evolution

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Tijana Z Grove studied physical chemistry at the University of Belgrade, Serbia and earned her Ph.D. in Chemistry from Iowa State University. She was an NIH postdoctoral fellow at Yale University with Lynne Regan, where she used protein engineering for assembly of stimuli-responsive biomaterials and scaffolds. While faculty in the Virginia Tech Chemistry Department, she established a nationally and internationally recognized research program at the intersection of chemistry, material science, and biotechnology. Currently, she is principal and founder of Zarkovic Grove Consulting, LLC specializing in protein engineering and nanoscience.

Thomas J Magliery earned his A.B. at Kenyon College, and his Ph.D. with Peter G. Schultz at the University of California, Berkeley, where he used directed evolution to help lay the foundations for in vivo unnatural amino acid mutagenesis. He was an NIH postdoctoral fellow at Yale University with Lynne Regan, and is currently an associate professor of chemistry and biochemistry at The Ohio State University. His lab uses high-throughput and statistical approaches to understand the determinants of protein stability and other physical properties, and also engineers enzymes, antibodies, and signaling molecules for applications as diagnostic and therapeutic agents. He is interested in the commercialization of academic intellectual property, and he recently obtained an M.B.A. at OSU’s Fisher College of Business.

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