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Re-usage of the Waste Drug as Molecular Chemosensor for Fe3+ Ion: Application towards Fluorescent Ink

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Abstract

Herein, a novel notion is used to reuse an expired drug namely Telmisartan (Sensor 2) to optically sense the Fe3+ metal ion. Direct re-usage of the drug avoided wearisome procedures of synthesis, hence proved the method as simple and economic. Sensor 2 found highly stable in the temperature range 25–75 °C. Relative fluorescence was almost the same even after 35 days of observation. There were no significant changes in wavelength even after adding different concentrations of FeCl3, which shows the high stability of the compound. The value of Limit of Detection (LOD) observed was 34.2 nM. FTIR studies confirmed the presence of carboxylic group. The method of fluorescence quenching was used to detect the Fe3+ ion. The association between Sensor 2 and Fe3+ was analyzed using Benesi-Hildebrand relation. Positive deviation from the linearity of S-V plots suggested that the quenching was not purely dynamic. Further, this deviation was analyzed by the sphere of action quenching model. To investigate whether the quenching is diffusion limited, we applied the finite sink approximation model and deduced that quenching is due to both static and dynamic processes. Due to the high fluorescence property of the molecule, it was successfully tested to be used as fluorescent ink.

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Acknowledgements

The authors thank for the financial support by Karnatak University Dharwad, under the scheme of URS (KU/SCH/URS/2018-19/361). Authors are also thankful to The Director and Technical staff of USIC, Dharwad for providing UV-Vis spectrometer, Fluorescence spectrophotometer and TCSPC instrument facilities. Authors oblige DST, New Dehli for providing FTIR spectrometer instrument facility under DST-PURSE-phase-ӏӏ program. [Grant No.SR/PURSE PHASE-2/13(G)] Authors are grateful to Mrs. J.M.Nirupama for guidance throughout the study.

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Present work is supported by funding under the scheme of URS (KU/SCH/URS/2018–19/361).

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Authors and Affiliations

  1. Department of Studies in Physics, Karnatak University Dharwad, Karnataka, 580003, India

    Aishwarya Nadgir, Malatesh S. Pujar & Ashok H. Sidarai

  2. Department of Physics, BLDE Association’s S.B Arts and KCP Science college Vijayapura, Karnataka, 586103, India

    Vani R. Desai

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  1. Aishwarya Nadgir
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Correspondence to Ashok H. Sidarai.

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Nadgir, A., Pujar, M.S., Desai, V.R. et al. Re-usage of the Waste Drug as Molecular Chemosensor for Fe3+ Ion: Application towards Fluorescent Ink. J Fluoresc 30, 1025–1033 (2020). https://doi.org/10.1007/s10895-020-02573-4

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