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Synthesis of 2H-Thiopirano[3,4-c]pyrazol-7-one Derivatives as the First Example a New Heterocyclic System

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Abstract

A series of ethyl 4-[(Z)-(4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-1-aryl-1H-pyrazole-3-carboxylates was obtained as a result of the reaction of ethyl 4-formyl-1-aryl-1H-pyrazole-3-carboxylates with rhodanine. Under the action of NaOH, the prepared pyrazole-3-carboxylates underwent recyclization to form 2-aryl-7-oxo-2,7-dihydrothiopyrano[3,4-c]pyrazole-5-carboxylic acids—the first representatives of new heterocyclic system.

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Authors and Affiliations

  1. Danylo Halytsky Lviv National Medical University, 79010, Lviv, Ukraine

    T. I. Chaban & Y. E. Matiichuk

  2. Ivan Franko National University of Lviv, 79005, Lviv, Ukraine

    V. S. Matiychuk

Authors
  1. T. I. Chaban
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  2. Y. E. Matiichuk
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  3. V. S. Matiychuk
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Correspondence to T. I. Chaban.

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Chaban, T.I., Matiichuk, Y.E. & Matiychuk, V.S. Synthesis of 2H-Thiopirano[3,4-c]pyrazol-7-one Derivatives as the First Example a New Heterocyclic System. Russ J Gen Chem 90, 1357–1361 (2020). https://doi.org/10.1134/S1070363220070257

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