Skip to main content
SpringerLink
Log in

Emodin-Containing MCM-41 Type Mesoporous Silica Nanoparticle Drug Delivery System

  • Published:
Theoretical and Experimental Chemistry Aims and scope

With the aim of developing drug delivery systems, it was shown that nanoparticles of mesoporous silica molecular sieve MCM-41 with average size 100-150 nm and specific surface 655 m2/g could include 202 mg of emodin per one gram of the carrier and release more than 85% of this compound at pH 8 during 48 h.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.
Fig. 2.
Fig. 3.
Fig. 4.
Fig. 5.
Fig. 6.

Similar content being viewed by others

References

  1. T. Yang, J. Wang, Y. Pang, et al., Mol. Med. Rep., 14, 4643 (2016), https://doi.org/10.3892/mmr.2016.5838.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. P. P. Campos, L. F. Fraceto, M. Ferreira, et al., Colloids Surf. B: Biointerfaces, 162, 69 (2018), https://doi.org/10.1016/j.colsurfb.2017.11.030.

    Article  CAS  PubMed  Google Scholar 

  3. S. A. Eid, M. A. Adams, T. Scherer, et. al., Eur. J. Pharmacol., 798, 77 (2017), https://doi.org/10.1016/j.ejphar.2017.01.022.

  4. A. Dahan and J. M. Miller, Am. Assoc. Pharm. Sci. J., 14, 244 (2012), https://doi.org/10.1208/s12248-012-9337-6.

    Article  CAS  Google Scholar 

  5. Y. Xu, C. Wang, G. Zhou, et al., Appl. Surf. Sci., 258, 6366 (2012), https://doi.org/10.1016/j.apsusc.2012.03.041.

    Article  CAS  Google Scholar 

  6. J. C. F., Karnopp, T. F. M. Cardoso, D. A. Gonçalves, et al., J. Biomater. Nanobiotechnol., 11, 1 (2020), https://doi.org/10.4236/jbnb.2020.111001.

    Article  CAS  Google Scholar 

  7. D. Halamova, M. Badanicova, V. Zelenak, et al., Appl. Surf. Sci., 256, 6489 (2010), https://doi.org/10.1016/j.apsusc.2010.04.044.

    Article  CAS  Google Scholar 

  8. M. Faheem, G. Mingyi, W. Aifei, et al., J. Colloid Interface Sci., 434, 1 (2014), https://doi.org/10.1016/j.jcis.2014.07.024.

    Article  CAS  Google Scholar 

  9. M. W. Ambrogio, M. Frasconi, M. D. Yilmaz, and X. Chen, Langmuir, 29, 15386 (2013), https://doi.org/10.1021/la402493q.

    Article  CAS  PubMed  Google Scholar 

  10. H. Zhang, M. A. Shahbazi, E. M. Makila, et al., Biomaterials, 34, 9210 (2013), https://doi.org/10.1016/j.biomaterials.2013.08.035.

    Article  CAS  PubMed  Google Scholar 

  11. C. K. Lee, S. S Liu, L. C. Juang, et al., J. of Hazardous Materials, 147, No. 3, 997 (2007), https://doi.org/10.1016/j.jhazmat.2007.01.130.

    Article  CAS  Google Scholar 

  12. J. L. Paris, M. V. Cabanas, M. Manzano, and M.Vallet-Regi, ACS Nano, 9, No. 11, 11023 (2015), https://doi.org/10.1021/acsnano.5b04378.

    Article  CAS  PubMed  Google Scholar 

  13. A. O. Jorgetto, S. P. Pereira, R. I. V. Silva, et al., Acta Chim. Slov., 62, 111 (2015), https://doi.org/10.17344/acsi.2014.787.

    Article  CAS  Google Scholar 

  14. J. C. P. Broekhoff, and J. H. de Boer, J. Catal., 10, No. 4, 377 (1968), https://doi.org/10.1016/0021-9517(68)90153-X.

    Article  CAS  Google Scholar 

  15. T. S. D. Almeida, K. E. Guima, R. M. Silveira, et al., RSC Adv., 7, 12006 (2017), https://doi.org/10.1039/C6RA28864B.

    Article  CAS  Google Scholar 

  16. C. Boissiere, D. Grosso, H. Amenitsch, et al., Chem. Commun., 22, 2798 (2003), https://doi.org/10.1039/B308694A.

    Article  Google Scholar 

  17. S. Lechevallier, J. Jorge, R. M. Silveira, et al., J. Nanomater., 60, 1 (2013), https://doi.org/10.1155/2013/918369.

    Article  CAS  Google Scholar 

  18. J. S. Beck, J. C. Vartuli, W. J. Roth, et al., J. Am. Chem. Soc., 114, No. 27, 10834 (1992), https://doi.org/10.1021/ja00053a020.

    Article  CAS  Google Scholar 

  19. K. S. W. Sing, D. H. Everett, R. A. W. Haul, et al., Pure Appl. Chem., 57, No. 4, 603 (1985), https://doi.org/10.1351/pac198557040603.

    Article  CAS  Google Scholar 

  20. M. Kruk and M. Jaroniec, Chem.Mater., 13, No. 10, 3169 (2001), https://doi.org/10.1021/cm0101069.

    Article  CAS  Google Scholar 

  21. M. Jaroniec and L. A. Solovyov, Langmuir, 22, No. 16, 6757 (2006), https://doi.org/10.1021/la0609571.

    Article  CAS  PubMed  Google Scholar 

  22. K. Mal, S. Chatterjee, A. Bhaumik, and C. Mukhopadhyay, Chem. Select., 4, No. 5, 1776 (2019), https://doi.org/10.1002/slct.201803708.

    Article  CAS  Google Scholar 

  23. P. Shah and S. J. Rajput, Drug Dev. Ind. Pharm., 45, No. 4, 587 (2019), https://doi.org/10.1080/03639045.2019.1569028.

    Article  CAS  PubMed  Google Scholar 

  24. H. Purwaningsih, Y. Ervianto, V. Pratiwi, et al., IOP Conf. Ser.: Mater. Sci. Eng., 515, 012051 (2019), https://doi.org/10.1088/1757-899X/515/1/012051.

    Article  CAS  Google Scholar 

  25. L. F. W. Brum, C. dos Santos, J. A. Gnoatto, et al., J. Drug Deliv. Sci. Technol., 53, 101210 (2019), https://doi.org/10.1016/j.jddst.2019.101210.

    Article  CAS  Google Scholar 

  26. M. A. U. Martines, M. R. Davolos. Jr. M. Jafelicci, et. al., J. Luminescence, 128, 1787 (2008), https://doi.org/10.1016/j.jlumin.2008.04.011.

    Article  CAS  Google Scholar 

  27. D. Singh, M. S. M. Rawat, A. Semalty, and M. Semalty, J. Therm. Anal. Calorim., 108, No. 1, 289 (2012), https://doi.org/10.1007/s10973-011-1759-3.

    Article  CAS  Google Scholar 

  28. S. Wang, T. Chen, R. Chen, et. al., Int. J. Pharm., 430, Nos. 1-2, 238 (2012), https://doi.org/10.1016/j.ijpharm.2012.03.027.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Chemistry, Federal University of Mato Grosso do Sul, Cidade Universitaria, Campo Grande, MS, 79074-460, Brazil

    I. M. D. dos Santos, S. P. Pereira, A. V. Mezacasa, O. I. A. Caceres, F. Timoteo, A. S. Lopes, K. F. del Pino, A. P. Duarte, H. U. Rashid & M. A. U. Martines

  2. Faculty of Pharmaceutical Sciences, Food and Nutrition, Federal University of Mato Grosso do Sul, Cidade Universitaria, Campo Grande, MS, 79070-900, Brazil

    T. F. M. Cardoso

  3. Institute of Biosciences, Sao Paulo State University, Botucatu, SP, 18618-689, Brazil

    G. R. de Castro

Authors
  1. I. M. D. dos Santos
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. P. Pereira
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. V. Mezacasa
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. O. I. A. Caceres
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. F. Timoteo
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. A. S. Lopes
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. K. F. del Pino
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. A. P. Duarte
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. T. F. M. Cardoso
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. G. R. de Castro
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. H. U. Rashid
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. M. A. U. Martines
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to M. A. U. Martines.

Additional information

Translated from Teoreticheskaya i Eksperimental’naya Khimiya, Vol. 56, No. 3, pp. 164-171, May-June, 2020.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

dos Santos, I.M.D., Pereira, S.P., Mezacasa, A.V. et al. Emodin-Containing MCM-41 Type Mesoporous Silica Nanoparticle Drug Delivery System. Theor Exp Chem 56, 174–182 (2020). https://doi.org/10.1007/s11237-020-09649-z

Download citation

  • Received:

  • Revised:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11237-020-09649-z

Keywords

Search

Navigation