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A ninhydrin–thiosemicarbazone based highly selective and sensitive chromogenic sensor for Hg2+ and F− ions

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Abstract

This study demonstrates the design, synthesis and sensing applications of a simple and efficient chemosensor, 2-(1,3-dioxo-1H-inden-2(3H)-ylidene)hydrazinecarbothioamide (R) for quick detection of Hg2+ and F− in aqueous media using a colorimetric test, UV–Vis spectral analysis, and silica gel support. Sensor R showed the typical absorption peak at 305 nm for Hg2+ which is responsible for color change from yellow to colorless, while in the case of F−, R exhibits a major peak at 415 nm and a color change from yellow to red. The limit of detection (LOD) of R for the analysis of Hg2+ was calculated as 1×10−6 M while for F−, it was found to be 3.4×10−7 M. The binding modes of R with Hg2+ and F− have been investigated by the Job’s plot, Benesi–Hildebrand (BH) method, 1H NMR, FTIR and theoretical studies. The sensor R was reversible after treating it with reagents such as EDTA and calcium nitrate solution after contacting with Hg2+ and F−, respectively. The performance of R can be successfully applied for the analysis of F− contents present in toothpastes.

Graphic abstract

A simple and efficient receptor ninhydrin-based Schiff’s base (R) for quick detection of Hg2+ and F− in aqueous medium using colorimetric and UV–Vis spectral analyses.

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Acknowledgements

Authors are grateful to the Department of Science and Technology, GOI for supporting the work through the project grant (EMR/2017/000816). Authors are also thankful to DST-VIT-FIST for NMR and GC-MS for research facilities.

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Authors and Affiliations

  1. Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore, 63 2014, India

    V Raju, R Selva Kumar & S K Ashok Kumar

  2. Center for Applied Science, Sree Vidyanikethan Engineering College, Tirupati, 517 102, India

    V Raju & G Madhu

  3. Department of Applied Chemistry, SV National Institute Technology, Surat, 395 007, India

    Shilpa Bothra & Suban K Sahoo

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  1. V Raju
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  2. R Selva Kumar
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  3. S K Ashok Kumar
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  4. G Madhu
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Correspondence to S K Ashok Kumar.

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Raju, V., Kumar, R.S., Kumar, S.K.A. et al. A ninhydrin–thiosemicarbazone based highly selective and sensitive chromogenic sensor for Hg2+ and F− ions. J Chem Sci 132, 89 (2020). https://doi.org/10.1007/s12039-020-01799-w

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  • DOI: https://doi.org/10.1007/s12039-020-01799-w

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