Abstract
It is found that ionic liquids (ILs) based on imidazole can be used as extractants in the dispersive liquid–liquid microextraction of combined pesticide preparations (imidacloprid, biphenthrin, cypermethrin, malathion, phosalone, and diazinon) followed by their determination by HPLC with electrospray ionization tandem mass spectrometry detection with. The effect of the IL (1-hexyl-3-methylimidazolium tetrafluoborate [C6MIM] [BF4], 1-hexyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide [C6MIM] [NTf2], 1‑butyl-3-methylimidazolium hexafluorophosphate, [C4MIM] [PF]6) nature and of the dispersive solvent (acetonitrile, methanol, acetone) volume, extraction time, pH of sample solution, and salting-out agent on the efficiency of analyte extraction is studied. It is found that the maximum recoveries (86–99%) of pesticides were reached using acetonitrile as a dispersive solvent and the [C4MIM] [PF]6 ionic liquid as an extractant. The absence of the effect of pH on the distribution of analytes between the water and organic phases confirms the distributive extraction mechanism. The effect of the ionic liquid on the ionization of pesticides is estimated, and conditions of the back extraction of pesticides to hexane are proposed for its reduction.
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REFERENCES
Wang, Q., Chen, R., Shatner, W., Cao, Y., and Bai, Y., Ultrason. Sonochem., 2019, vol. 51, p. 369.
Saraji, M. and Boroujeni, M.K., Anal. Bioanal. Chem., 2014, vol. 406, no. 8, p. 2027.
Smirnova, S.V. and Pletnev, I.V., J. Anal. Chem., 2019, vol. 74, no. 1, p. 1.
Pletnev, I.V., Smirnova, S.V., and Shvedene, N.V., J. Anal. Chem., 2019, vol. 74, no. 7, p. 625.
Spietelun, A., Marcinkowski, L., de la Guardia, M., and Namieśnik, J., Talanta, 2014, vol. 119, no. 15, p. 34.
Escudero, L.B., Grijalba, A.C., Martinis, E.M., and Wuilloud, R.G., Anal. Bioanal. Chem., 2013, vol. 405, no. 24, p. 7597.
Trujillo-Rodríguez, M.J., Rocío-Bautista, P., Pino, V., and Afonso, A.M., TrAC,Trends Anal. Chem., 2013, vol. 51, p. 87.
Han, D., Tang, B., Lee, Y.R., and Row, K.H., J. Sep. Sci., 2012, vol. 35, no. 21, p. 2949.
Ventura, S.P.M., e Silva, F.A., Quental, M.V., Mondal, D., Freire, M.G., and Coutinho, J.A.P., Chem. Rev., 2017, vol. 117, no. 10, p. 6984.
Rykowska, I., Ziemblińska, J., and Nowak, I., J. Mol. Liq., 2018, vol. 259, p. 319.
Kolobova, E.A., Kartsova, L.A., Kravchenko, A.V., and Bessonova, E.A., Talanta, 2018, vol. 188, p. 183.
Berthod, A., Ruiz-Ángel, M.J., and Carda-Broch, S., J. Chromatogr. A, 2008, vol. 1184, nos. 1–2, p. 6.
Kolobova, E.A., Kartsova, L.A., Bessonova, E.A., and Kravchenko, A.V., Analitika Kontrol’, 2017, vol. 21, no. 1, p. 57.
Shashkov, M.V. and Sidel’nikov, V.N., J. Chromatogr. A, 2013, vol. 1309, no. 27, p. 56.
Patel, D.D. and Lee, J.M., Chem. Rec. (New York, N.Y.), 2012, vol. 12, no. 3, p. 329.
De Boeck, M., Damilano, G., Dehaen, W., Tytgat, J., and Cuypers, E., Talanta, 2018, vol. 184, p. 369.
Li, Z., Chen, F., Wang, X., and Wang, C., Biomed. Chromatogr., 2012, vol. 27, no. 2, p. 254.
Liu, Y., Zhao, E., Zhu, W., Gao, H., and Zhou, Z., J. Chromatogr. A, 2009, vol. 1216, no. 6, p. 885.
He, L., Luo, X., Xie, H., Wang, C., Jiang, X., and Lu, K., Anal. Chim. Acta, 2009, vol. 655, nos. 1–2, p. 52.
Cruz-Vera, M., Lucena, R., Cárdenas, S., and Valcárcel, M., J. Chromatogr. A, 2009, vol. 1216, no. 37, p. 6459.
Ravelo-Pérez, L.M., Hernández-Borges, J., Asensio-Ramos, M., and Rodríguez-Delgado, M.A., J. Chromatogr. A, 2009, vol. 1216, no. 43, p. 7336.
Zhou, Q., Bai, H., Xie, G., and Xiao, J., J. Chromatogr. A, 2008, vol. 1188, no. 2, p. 148.
Zhou, Q., Zhang, X., Xie, G., and Xiao, J., J. Sep. Sci., 2009, vol. 32, no. 22, p. 3945.
Zhang, J., Gao, H., Peng, B., Li, S., and Zhou, Li., J. Chromatogr. A, 2011, vol. 1218, no. 38, p. 6621.
Li, S., Gao, H., Zhang, J., Li, Y., Peng, B., and Zhou, Z., J. Sep. Sci., 2011, vol. 34, no. 22, p. 3178.
Berthod, A., Ruiz-Ángel, M.J., and Carda-Broch, S., J. Chromatogr. A, 2018, vol. 1559, p. 2.
Kolobova, E.A. and Kartsova, L.A., Analitika Kontrol’, 2018, vol. 22, no. 3, p. 284.
Jensen, M.P., Neuefeind, J., Beitz, J.V., Skanthakumar, S., and Soderholm, L., J. Am. Chem. Soc., 2003, vol. 125, no. 50, p. 15466.
Dietz, M.L. and Stepinski, D.C., Talanta, 2008, vol. 75, no. 2, p. 598.
De Boeck, M., Missotten, S., Dehaen, W., Tytgat, J., and Cuypers, E., Forensic Sci. Int., 2017, vol. 274, p. 44.
Yaroshenko, D.V. and Kartsova, L.A., J. Anal. Chem., 2014, vol. 69, no. 4, p. 311.
Schwanz, T.G., Carpilovsky, C.K., Weis, G.C.C., and Costabeber, I.H., J. Chromatogr. A, 2019, vol. 1585, p. 10.
ACKNOWLEDGMENTS
We are grateful to Resource Education Center in Chemistry of St. Petersburg State University for the provided equipment.
Funding
This work was supported by the Russian Foundation for Basic Research, project no. 18-53-80010 BRICS_t.
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Translated by E. Rykova
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Bessonova, E.A., Deev, V.A. & Kartsova, L.A. Dispersive Liquid–Liquid Microextraction of Pesticides Using Ionic Liquids As Extractants. J Anal Chem 75, 991–999 (2020). https://doi.org/10.1134/S1061934820080043
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DOI: https://doi.org/10.1134/S1061934820080043