Highly selective piezoresistive sensor for mercury (Hg²⁺) ions detection using mercaptosuccinic acid-functionalized microcantilevers with cross-linked pyridinedicarboxylic acid

This paper aims to report an insightful portable microfluidic system for rapid and selective sensing of Hg²⁺ in the picomolar (pM) concentration using microcantilever-based piezoresistive sensor. The detection time for various laboratory-based techniques is generally 12–24 h. The majority of modules used in the proposed platform are battery oriented; therefore, they are portable and handy to carry-out on-field investigations.

In this study, the authors have incorporated the benefit of three technologies, i.e. thin-film, nanoparticles (NPs) and micro-electro-mechanical systems, to selectively capture the Hg²⁺ at the pM concentration. The morphology and topography of the proposed sensor are characterized using field emission scanning electron microscopy and verification of the experimental results using energy dispersive X-ray.

The proposed portable microfluidic system is able to perform the detection in 5 min with a limit of detection (LOD) of 0.163 ng (0.81 pM/mL) for Hg²⁺, which perfectly describes its excellent performance over other reported techniques.

A microcantilever-based technology is perfect for on-site detection, and a LOD of 0.163 ng (0.81 pM/mL) is outstanding compared to other techniques, but the fabrication of microcantilever sensor is complex.

Many researchers used NPs for heavy metal ions sensing, but the excess usage and industrialization of NPs are rapidly expanding harmful consequences on the human life and nature. Also, the LOD of the NPs-based method is limited to nanomolar concentration. The suggested microfluidic system used the benefit of thin-film and microcantilever devices to provide advancement over the NPs-based approach and it has a selective sensing in pM concentration.