Phytochemicals containing biologically active polyphenols as an effective agent against Covid-19-inducing coronavirus
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Graphical abstract
Keywords
Plant extracts
Phytochemicals
Bioactivity
Polyphenols
Antiviral
Pandemic
Coronavirus
Abbreviations
3CLpro
3C-like protease
ACE2
Angiotensin-converting enzyme 2
CBE
CBM, Herbal extracts from Rhizoma Cibotii
CC50
50% cytotoxicity concentration
CDC
Cholesterol-dependent cytolysin
Covid-19
Coronavirus Disease 2019
CPE
Cytopathogenic effect
CTH
Herbal extract from Cassiae Semen
DBM
Herbal extract from Dioscoreae Rhizoma
DNA
Deoxyribonucleic acid
EC50
50% effective concentration
FA
Fatty acid
FFA
Free fatty acid
GCG
Gallocatechin gallate
GSH
Herbal extract from Gentianae Radix
IC50
50% inhibitory concentrations
MERS-CoV
Middle East Respiratory Syndrome Coronavirus
Mpro
The major protease
MNP
Marine Natural Product
MTT test
Cytotoxicity test using 3- (4,5-dimethylthiazol-2-yl) −2,5-diphenyltetrazolium bromide
PLpro
The papain-like protease
PLY
Pneumolysin
RNA
Ribonucleic acid
SARS-CoV
Severe Acute Respiratory Syndrome coronavirus
TCH
Herbal extract from Loranthi Ramus
WHO
World Health Organization
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© 2020 Published by Elsevier Ltd.