Short communicationOral immunization of carps with chitosan–alginate microcapsule containing probiotic expressing spring viremia of carp virus (SVCV) G protein provides effective protection against SVCV infection
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CRediT authorship contribution statement
Shuo Jia: Data curation, Methodology, Software, Writing - original draft. Kun Zhou: Formal analysis, Investigation, Methodology. Ronghui Pan: Conceptualization, Funding acquisition, Project administration, Resources, Validation. Jing Wei: Investigation, Resources, Validation. Zhongmei Liu: Resources. Yigang Xu: Conceptualization, Funding acquisition, Project administration, Supervision, Writing - review & editing.
Acknowledgements
This work was funded by the National Key R&D Program of China (grant 2017YFD0501105), the National Natural Science Foundation of China (grant number 31672591), and “Academic Backbone” Project of Northeast Agricultural University Scholar Program (grant number 18XG24).
References (10)
- et al.
Determination of the complete genomic sequence and analysis of the gene products of the virus of spring viremia of carp, a fish rhabdovirus
Virus Res.
(2002) - et al.
Modulatory effect of CpG oligodeoxynucleotide on a DNA vaccine against nervous necrosis virus in orange-spotted grouper (Epinephelus coioides)
Fish Shellfish Immunol.
(2015) - et al.
DNA vaccines as a tool for analysing the protective immune response against rhabdoviruses in rainbowtrout
Fish Shellfish Immunol.
(2002) - et al.
Dendritic cell targeting of bovine viral diarrhea virus E2 protein expressed by Lactobacillus casei effectively induces antigen-specific immune responses via oral vaccination
Viruses
(2019) - et al.
Recombinant lactobacillus expressing G protein of spring viremia of carp virus (SVCV) combined with ORF81 protein of koi herpesvirus (KHV): a promising way to induce protective immunity against SVCV and KHV infection in cyprinid fish via oral vaccination
Vaccine
(2015)
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Control of spring viremia of carp in common carp using RNA interference
2022, AquacultureCitation Excerpt :RNAi can be mediated by the generation of siRNAs of 21–23 nucleotides in length from longer dsRNA or micro RNA (miRNAs) by a protein known as dicer (ribonuclease III) (Hannon, 2002; Aliyari and Ding, 2009), results finally in specific degradation of messenger RNA (mRNA) and the expression of its encoded protein cannot proceed (Fire et al., 1998; Elbashir et al., 2001). Despite significant advances that have been made to the control strategies of SVCV (Siwicki et al., 2003; Lorenzen and LaPatra, 2005; Shen et al., 2018, 2019; Liu et al., 2020; Jia et al., 2020) and other viral diseases, the effectiveness of current drugs and vaccines are limited because of many factors such as complexity, toxicity, cost and imposed the of developing drug resistance (Dave and Pomerantz, 2003). Conversely, RNAi based technology has potentials and advantages over the control strategies including the high efficiency of the gene knockdown and the ability to specifically target the gene of interest (Bumcrot et al., 2006).
The functionality of probiotics in aquaculture: An overview
2021, Fish and Shellfish ImmunologyCitation Excerpt :Chitosan-alginate-based microcapsules containing probiotic vaccine, expressing G protein of spring viremia of carp virus (SVCV), have been shown to induce potent immune responses and provide effective anti-SVCV protection in carp. Hence, the use of probiotics in the form of vaccines is also advocated for fish immunization via large-scale oral vaccination [139]. A diet supplemented with L. acidophilus improved gut morphometry (including better length, width, and areas of absorption by villi) and boosted antioxidant potential and the immune response in terms of improved levels of superoxide dismutase, catalase, expression of transforming growth factor-beta (TGFβ), interleukin 8 (IL-8), and tumor necrosis factor-alpha (TNF-alpha) in juveniles of the common carp (Cyprinus carpio) [140].
Mucosal immunoglobulins of teleost fish: A decade of advances
2021, Developmental and Comparative ImmunologyCitation Excerpt :In this type of vaccine delivery system, probiotics engineered to express G protein of spring viremia of carp (SVCV) induced high antigen-specific IgM titers in serum after 14, 28, 42 and 56 dpv. The vaccine reduced mortalities by 80% upon challenge with SVCV 42 dpv (Jia et al., 2020). Following a similar strategy, common carp larvae of 18 days post-hatch were orally immunized against cyprinid herpesvirus-3 (CyHV-3) using live Artemia previously fed with Saccharomyces cerevisiae expressing viral PORF65 tagged with GFP.