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The effect of Ag and clay nanoparticles on the antimicrobial activity of gamma-irradiated alginate/pectin beads

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Abstract

In spite of the intensive work done on the preparation, characterization and applications of silver nanoparticles, the problems limit its use, still under study. One of these solutions is embedding Ag NPs in natural polymers to decrease aggregation, control its toxicity and size, and to increase its stability as well. In this respect, ionically cross-linked alginate/pectin (ALG/PEC) beads containing silver and clay nanoparticles, with different compositions were prepared. Silver nanoparticles have been obtained with hydrogel networks as nonreactors via in situ reduction of pre-adsorbed silver ions onto (ALG/PEC) beads matrix, using gamma irradiation. The effects of the composition of the two polymers, concentration of CaCl2 as a crosslinking agent on the formation of cross-linked beads were studied. Characterization of (ALG/PEC) beads, (ALG/PEC)/Ag and (ALG/PEC)/Clay-Ag nanocomposite beads were performed using scanning electron microscopy, transmission electron microscopy and X-ray diffraction (XRD). The XRD pattern obtained confirmed the presence of diffraction peaks related to Ag NPs and nanoclay. The antimicrobial activity, toward different micro-organisms of the prepared nanocomposite beads was examined. The Beads containing both Ag NPs and Nanoclay exhibited the highest antimicrobial activity for the different organisms chosen for the antimicrobial test.

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Acknowledgements

The authors are very grateful to assist, prof., Heba El Bialy, Assis., professor of microbiology, for her great help in the antimicrobial test.

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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Authors and Affiliations

  1. Polymer Chemistry Department, National Center for Radiation Research and Technology, Egyptian Atomic Energy Authority, P.O. Box 9621, Nasr City, Cairo, Egypt

    Faten Ismail Abou El Fadl & Sayeda Mohamed Ibrahim

  2. Radiation Chemistry Department, National Center for Radiation Research and Technology, Egyptian Atomic Energy Authority, P.O. Box 9621, Nasr City, Cairo, Egypt

    Faten Ismail Abou El Fadl & Sayeda Mohamed Ibrahim

Authors
  1. Faten Ismail Abou El Fadl
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  2. Sayeda Mohamed Ibrahim
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Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by FIAEF, and SMI. The first draft of the manuscript was written by FIAEF and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

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Correspondence to Faten Ismail Abou El Fadl.

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Abou El Fadl, F.I., Ibrahim, S.M. The effect of Ag and clay nanoparticles on the antimicrobial activity of gamma-irradiated alginate/pectin beads. J Nanostruct Chem 10, 243–253 (2020). https://doi.org/10.1007/s40097-020-00345-x

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