* Corresponding authors

^a Department of Biomedical Engineering, University of Texas, Austin, TX, USA
E-mail: peppas@che.utexas.edu

^b McKetta Department of Chemical Engineering, University of Texas, Austin, TX, USA

^c Institute for Biomaterials, Drug Delivery, and Regenerative Medicine University of Texas, Austin, TX, USA

^d Department of Pediatrics, Dell Medical School, Austin, TX, USA

^e Department of Surgery and Perioperative Care, Dell Medical School, Austin, TX, USA

^f Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas, Austin, TX, USA