Abstract
Tight junctions are almost impermeable structures located near the apical border of epithelial cells; increase in the permeability of mammary gland cells’ tight junctions may alter milk composition and its suitability for industrialization. Sixteen Holstein dairy cows were studied to evaluate mammary gland cells’ tight junction permeability (indicated by plasma lactose levels) from cows producing stable or unstable milk to ethanol at 72 °GL concentration. Rectal temperature, respiratory rate and milk parameters were also compared and weather conditions (temperature–humidity index) monitored. Temperature–humidity index did not vary for cows producing stable or unstable milk, so there were no differences in physiological traits. Cows producing unstable milk presented elevated tight junctions’ permeability, probably due to higher days in milk. The odds of cows producing unstable milk (clots formation when mixed with ethanol below or equal 72 °GL) increases according to elevations in days in milk and tight junction permeability.
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Funding
Study was financed by CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnológico) and CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior).
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Approved by The Research Committee and Ethical Committee for Animal Use of the Federal University of Rio Grande do Sul (22773/2012).
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Stumpf, M.T., Fischer, V., Daltro, D.S. et al. Mammary gland cell’s tight junction permeability from dairy cows producing stable or unstable milk in the ethanol test. Int J Biometeorol 64, 1981–1983 (2020). https://doi.org/10.1007/s00484-020-01967-0
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DOI: https://doi.org/10.1007/s00484-020-01967-0