Abstract
From an EtOAc-soluble fraction of the stem barks of Swintonia floribunda (Anacardiaceae), decumbic anhydride (1) and four known compounds 2–5 were isolated. Their chemical structures were elucidated based on the spectroscopic data interpretation. The GIAO-DFT calculation of 13C NMR chemical shifts was carried out to clarify the structure of 1. The absolute configuration of 1 was assigned based on the Cotton effects in its ECD spectrum. Compound 1 showed potent tyrosinase inhibitory activity with an IC50 value of 52.2 μM.
Funding source: Viet Nam National University Ho Chi Minh City
Award Identifier / Grant number: C2019-18-12
Acknowledgments
This research is funded by Vietnam National University Ho Chi Minh City (VNUHCM) under grant number C2019-18-12, to Phu Hoang Dang.
Author contribution: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: This research is funded by Vietnam National University Ho Chi Minh City (VNUHCM) under grant number C2019-18-12, to Phu Hoang Dang.
Conflict of interest statement: The authors declare no conflicts of interest regarding this article.
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Supplementary material
Conformational data of decumbic acid (Table S1) and copies of spectroscopic data for 1 (Figures S1–S5).
The online version of this article offers supplementary material (https://doi.org/10.1515/znc-2020-0136).
© 2020 Walter de Gruyter GmbH, Berlin/Boston
