Abstract
This study reports ascorbic acid adsorption/release performance and antibacterial activity of chitosan composite microcapsules containing terpolymer of glycidyl methacrylate (GMA), maleic anhydride (MA) and N-tert-butylacrylamide (NTBA). The effects of amount of chitosan composite microcapsules, solution pH, ascorbic acid concentration and contact time on the adsorption of ascorbic acid by chitosan-ter (GMA-MA-NTBA) polymer microcapsules were studied. The maximum ascorbic acid adsorption was observed for 0.075 g of microcapsules under following conditions; ascorbic acid concentration: 10 mg L−1, pH 7.35, temperature: 35 °C and contact time: 1 h. Antibacterial activity of chitosan-ter (GMA-MA-NTBA) polymer microcapsules was tested against Pseudomonas aeruginosa ATCC 27853, Escherichia coli ATCC 25113, Klebsiella pneumoniae ATCC 700603, Staphylococcus aureus ATCC 25923, Enterococcus faecalis ATCC 29212 and Salmonella enteritidis ATCC 13076 bacterial strains. In vitro antibacterial studies demonstrated that chitosan microcapsules with 0.25% ter (GMA-MA-NTBA) polymer (by mass) were more effective on inhibiting of bacterial growth. Plain glutaraldehyde-chitosan beads showed no antibacterial activity, indicating that ter(GMA-MA-NTBA) polymer content was responsible for the antibacterial activity of the chitosan-ter(GMA-MA-NTBA) polymer microcapsules.
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Ahmed S, Ali A, Sheikh J (2018) Int J Biol Macromol 116:849–862
Kalantari K, Afifi AM, Jahangirian H, Webster TJ (2018) Carbohyd Polym 207:588
Sinha VR, Singla AK, Wadhawan S, Kaushik R, Kumria R, Bansal K, Dhawan S (2004) Int J Pharm 274:1–33
El Knidri H, Belaabed R, Addaou A, Laajeb A, Lahsini A (2018) Int J Biol Macromol 120:1181
Ali A, Ahmed S (2018) Int J Biol Macromol 109:273–286
Xu J, Strandman S, Zhu JX, Barralet J, Cerruti M (2015) Biomaterials 37:395–404
Khdair A, Hamad I, Alkhatib H, Bustanji Y, Mohammad M, Tayem R, Aiedeh K (2016) Eur J Pharm Sci 93:38–44
Mahmoodzadeh F, Jannat B, Ghorbani M (2019) Int J Biol Macromol 126:517–524
Meng Q, Man Z, Dai L, Huang H, Zhang X, Hu X, Shao Z, Zhu J, Zhang J, Fu X (2015) Sci Rep 5:17802
Facchi DP, Cazetta AL, Canesin EA, Almeida VC, Bonafé EG, Kipper MJ, Martins AF (2018) Chem Eng J 337:595–608
Elgadir MA, Uddin MS, Ferdosh S, Adam A, Chowdhury AJK, Sarker MZI (2015) J Food Drug Anal 23:619–629
Patil SB, Inamdar SZ, Reddy KR, Raghu AV, Soni SK, Kulkarni RV (2019) J Microbiol Methods 159:200–210
Sadeghi-Kiakhani M, Safapour S, Ghanbari-Adivi F (2019) Int J Biol Macromol 134:1170–1178
Pathania D, Gupta D, Kothiyal N, Eldesoky G, Naushad M (2016) Int J Biol Macromol 84:340–348
Pathania D, Gupta D, Agarwal S, Asif M, Gupta VK (2016) Mater Sci Eng, C 64:428–435
Shimoni E (2004) J Food Sci 69:R160–R166
Zielinski H, Kozlowska H, Lewczuk B (2001) Innov Food Sci Emerg Technol 2:159–169
Champagne CP, Fustier P (2007) Curr Opin Biotechnol 18:184–190
Cho Y, Shim H, Park J (2003) J Food Sci 68:2717–2723
Jang K-I, Lee HG (2008) J Agric Food Chem 56:1936–1941
Desai K, Park HJ (2006) J Microencapsul 23:91–103
Alishahi A, Mirvaghefi A, Tehrani M, Farahmand H, Shojaosadati S, Dorkoosh F, Elsabee MZ (2011) Food Chem 126:935–940
Yue P, Tricard S, He S, Wang N, Zhao J, Fang J, Shen W (2016) Electroanalysis 28:1340–1347
Özdemir KS, Gökmen V (2017) LWT Food Sci Technol 76:172–180
Najafi-Taher R, Derakhshan MA, Faridi-Majidi R, Amani A (2015) RSC Adv 5:50462–50469
Li J, Wu Y, Zhao L (2016) Carbohyd Polym 148:200–205
Verlee A, Mincke S, Stevens CV (2017) Carbohyd Polym 164:268–283
Delezuk JA, Ramírez-Herrera DE, de Ávila BE-F, Wang J (2017) Nanoscale 9:2195–2200
Kong M, Chen XG, Xing K, Park HJ (2010) Int J Food Microbiol 144:51–63
Ma Z, Garrido-Maestu A, Jeong KC (2017) Carbohyd Polym 176:257–265
Berger J, Reist M, Mayer JM, Felt O, Peppas N, Gurny R (2004) Eur J Pharm Biopharm 57:19–34
Mageswari S, Subramanian K (2012) Polymer 51:1296–1302
Jeong J-H, Byoun Y-S, Lee Y-S (2002) React Funct Polym 50:257–263
Badrossamay MR, Sun G (2009) Polym Eng Sci 49:359–368
Sargin İ (2019) Selçuk Üniversitesi Mühendislik, Bilim ve Teknoloji Dergisi 7:524–535
Kleinstreuer C, Zhang Z, Li Z (2008) Respir Physiol Neurobiol 163:128–138
Beck-Broichsitter M, Gauss J, Packhaeuser CB, Lahnstein K, Schmehl T, Seeger W, Kissel T, Gessler T (2009) Int J Pharm 367:169–178
Park S, Wexler A (2008) J Aerosol Sci 39:266–276
Yang W, Peters JI, Williams RO III (2008) Int J Pharm 356:239–247
Esposito E, Cervellati F, Menegatti E, Nastruzzi C, Cortesi R (2002) Int J Pharm 242:329–334
Dev A, Binulal N, Anitha A, Nair S, Furuike T, Tamura H, Jayakumar R (2010) Carbohyd Polym 80:833–838
Stevanović M, Savić J, Jordović B, Uskoković D (2007) Colloids Surf B 59:215–223
ISO, International Organization for Standardization (2006)
Rzaev ZM (1999) J Polym Sci A 37:1095–1102
Pehlivan E, Arslan G (2007) Fuel Process Technol 88:99–106
Rzayev ZM (2011) arXiv:1105.1260
Benhabiles M, Salah R, Lounici H, Drouiche N, Goosen M, Mameri N (2012) Food Hydrocolloids 29:48–56
Goy RC, Britto DD, Assis OB (2009) Polímeros 19:241–247
Bruice PY (2011) Organic Chemistry, International edn. Pearson-Prentice Hall, Upper Saddle River
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The authors are thankful to Selcuk University Research Foundation (Project Number: BAP-17401077) for funding the study.
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Ciftci, N., Sargin, I., Arslan, G. et al. Ascorbic Acid Adsorption-Release Performance and Antibacterial Activity of Chitosan-ter(GMA-MA-NTBA) Polymer Microcapsules. J Polym Environ 28, 2277–2288 (2020). https://doi.org/10.1007/s10924-020-01773-0
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DOI: https://doi.org/10.1007/s10924-020-01773-0