Theoretic and experimental study of viscoelastic properties of the whole blood exposed to shear stress was carried out with acoustic resonance method based on the measurement of gain-frequency characteristics of resonating needle in an ARP-01M piezoelectric thromboelastograph (Mednord). The study revealed regularities in the changes of viscoelastic parameters of the whole blood within 0-80 kHz frequency range of shear vibrations. In this frequency range, the elastic (storage) modulus G’ reflecting blood elasticity increased with frequency and significantly contributed to the complex viscosity coefficient. The revealed gain-frequency regularities open the vista to employ the acoustic resonance method to determine the viscoelastic parameters of the whole blood and their coagulation-induced changes in the wide frequency range of shear vibrations.
Similar content being viewed by others
References
Demkin VP, Mel’nichuk SV, Rudenko TV, Tyutrin II, Udut VV. Analysis of Viscoelastic Parameters of Fluids by Low-Frequency Piezoelastography. Bull. Exp. Biol. Med.2020;168(3):413-417. doi: https://doi.org/10.1007/s10517-020-04721-z
Demkin VP, Melnichuk SV, Udut VV, Demkin OV, Tyutrin II. Physical Principles of the Method of Low-Frequency Piezothromboelastography for Studying Rheological Properties of Whole Blood. Russ. Physics J. 2019;62(6):972-983.
Konovalov SI, Kuz’menko AG. Determination of resonance and antiresonance frequencies for plate-type transducers made of piezoceramics, on the base of its input electric impedance frequency response. Izv. Sankt-Peterburg. Gos. Elektrotekhn. Univer. “LETI”. 2018;(2):56-61. Russian.
Matveenko VN, Kirsanov EA. The viscosity and structure of dispersed systems. Moscow University Chemistry Bulletin. 2011;66(4):199-228.
Solovyev MA, Udut VV, Tutrin II, Karchagina OS. Pharmacodynamics of antiplatelet agents used for correction of thrombotic complications in polytrauma. Med.-Biol. Sots.-Psikhol. Probl. Bezopasnosti Chrezvuch. Situatsiyakh. 2015;(1):96-102. Russian.
Tyutrin II, Udut VV. Low-Frequency Piezothromboelastography of Whole Blood: Algorithms for Diagnosis and Correction of Hemostasiological Disorders. Tomsk, 2016. Russian.
Derjaguin BV, Bazaron UB, Lamazhapova KD, Tsidypov BD. Shear elasticity of low-viscosity liquids at low frequencies. Phys. Rev. A. 1990;42(4):2255-2258.
Hund SJ, Kameneva MV, Antaki JF. A quasi-mechanistic mathematical representation for blood viscosity. Fluids. 2017;2(1). doi:https://doi.org/10.3390/fluids2010010
Mimouni Z. The rheological behavior of human blood-comparison of two models. Open J. Biophysics. 2016;6(2):29-33.
Versteeg HH, Heemskerk JW, Levi M, Reitsma PH. New fundamentals in hemostasis. Physiol. Rev. 2013;93(1):327-358.
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 169, No. 2, pp. 260-264, February, 2020
Rights and permissions
About this article
Cite this article
Demkin, V.P., Mel’nichuk, S.V., Gavar, A.V. et al. Spectral Regularities of Viscoelastic Parameters of Whole Blood Exposed to Periodic Shear Stress. Bull Exp Biol Med 169, 293–296 (2020). https://doi.org/10.1007/s10517-020-04871-0
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-020-04871-0