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Evaluation of the medial rectus muscle and optic nerve using strain and shear wave elastography in Graves' patients

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Abstract

Purpose

The purpose of this study was to describe the elastic properties of the medial rectus muscle and optic nerve in Graves’ patients without clinically apparent ophthalmopathy using strain elastography (SE) and shear wave elastography (SWE) and to determine whether these elastic properties could be used to aid in the diagnosis of the medial rectus muscle or optic nerve involvement.

Materials and methods

Thirty participants diagnosed with Graves’ disease without ophthalmopathy and 30 healthy volunteers (control group) were prospectively examined between November 2018 and August 2019. SE and SWE findings in both groups were compared using the χ2 test and the independent samples t test.

Results

A statistically significant softening of the medial rectus muscle was observed in the SE patterns of the Graves’ patients (p = 0.009). A statistically appreciable distinction was observed between the medial rectus muscle (7.64 ± 2.1 and 9.20 ± 1.7 kPa, p = 0.000) and the optic nerve (8.35 ± 2.8 and 9.37 ± 1.5 kPa, p = 0.019) in the SWE modulus of the Graves’ patients and healthy volunteers.

Conclusion

SE and SWE can be used to identify structural alterations to the medial rectus muscle and optic nerve before clinically apparent Graves’ ophthalmopathy has developed.

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Funding

This work was supported by Scientific Research Projects Coordination Unit of Kirikkale University Project number 2019/002.

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Authors and Affiliations

  1. Faculty of Medicine, Radiology Department, Kirikkale University, Kirikkale, Turkey

    Adnan Özdemir, Neşe Asal & Mikail İnal

  2. Faculty of Medicine, Radiology Department, Gaziantep University, Gaziantep, Turkey

    Mehmet H. Şahan

  3. Faculty of Medicine, Endocrinology and Metabolism Department, Kirikkale University, Kirikkale, Turkey

    Aşkın Güngüneş

Authors
  1. Adnan Özdemir
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  2. Mehmet H. Şahan
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  3. Neşe Asal
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  4. Mikail İnal
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  5. Aşkın Güngüneş
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Correspondence to Adnan Özdemir.

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Özdemir, A., Şahan, M.H., Asal, N. et al. Evaluation of the medial rectus muscle and optic nerve using strain and shear wave elastography in Graves' patients. Jpn J Radiol 38, 1028–1035 (2020). https://doi.org/10.1007/s11604-020-01014-3

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  • DOI: https://doi.org/10.1007/s11604-020-01014-3

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