Elsevier

Chemosphere

Volume 259, November 2020, 127476
Chemosphere

Review
Emerging disinfection byproducts: A review on their occurrence and control in drinking water treatment processes

https://doi.org/10.1016/j.chemosphere.2020.127476Get rights and content

Highlights

  • Emerging DBPs occur in low concentrations and are not removed by conventional water treatments.

  • DBPs classification, analysis, fate, health effects and regulations are reviewed.

  • Advanced water treatement processes implemented at pilot-scale are critically analyzed.

  • The control of emerging DBPs relies on precursors’ removal and on water treatment process’ tuning.

  • Main challenges of emerging DBPs removal are their low amounts and cost/effectiveness at full scale.

Abstract

The occurrence of disinfection byproducts (DBPs) is related both to drinking water treatment (DWT) processes and to raw water’s characteristics. Emerging pollutants typically occur in low concentrations and are not removed by conventional DWT processes. Emerging DBPs appear within the DWT or in the distribution system due to the combination of disinfection agents (especially chlorine) with precursors as: natural organic matter (NOM), algal organic matter (AOM), anthropogenic contaminants (pesticides, pharmaceuticals, detergents etc.), brominated and iodinated compounds.

This study has as main goal a consistent analysis of the major problems caused by emerging DBPs to drinking water supplies. It presents a comprehensive review of the research efforts related to emerging DBPs considering three viewpoints: 1. an overview of their classification, legislative framework, methods of analysis, disinfection operational conditions and removal processes; 2. their occurrence, fate, health effects and impacts; 3. the analysis of the advanced DWT processes that might be used for the removal and control of precursors and DBPs, with a focus on pilot and full-scale installations. All presented case studies considered pollutants removed, process conditions and efficiencies, and a critical assessment of processes based on membranes, advanced oxidation and adsorption on activated carbon or other materials. The main challenges of the control and removal of emerging DBPs are their low concentrations and the technical and economic sustainability of their application at full-scale, which need to be carefully adapted to local boundary conditions.

Introduction

A major accomplishment for the protection of human health is the production of safe drinking water from raw surface and ground waters. Drinking water sources have thus become a priority for environmental communities worldwide. Water disinfection plays a pivotal role in reducing serious illnesses associated with waterborne diseases. Disinfection is used to eliminate pathogenic microorganisms during the drinking water treatment (DWT) and to ensure in the distribution network the quality parameters for a safe drinking water consumption (Chau et al., 2018). DWT companies must assume the responsibility for water safety and at the same time for the implementation of the most efficient technologies to warrant that all qualitative indicators are below the limits imposed by the regulations.

Most common chemical disinfectants are chlorine-based (e.g. chlorine, chlorine dioxide, hypochlorite salts), having the advantages of low cost and easy manipulation, high efficiencies towards different pathogens, taste improvement and persistence in the distribution network. However, disinfection byproducts (DBPs) often occur after chlorine-based disinfection processes (Gupta and Ali, 2013), implying possible adverse effects and risks to human health. Many precursors, as natural organic matter (NOM), algal organic matter (AOM), anthropogenic contaminants (e.g. pesticides, pharmaceuticals, detergents, etc.), brominated and iodinated compounds, as well as upstream wastewater discharges, and DWT operational parameters (disinfection agent type and/or dose, pH, contact time, temperature) may contribute to the development of DBPs (Alexandrou et al., 2018). Precursors’ presence and amount could be subjected to seasonal variations (e.g. for AOM or contaminants related to agricultural activities, as ammonium and pesticides). DBPs are classified “harmful for human health” and their occurrence in raw water sources imposes special monitoring and efforts for the water companies (WHO, 2017).

In order to avoid DBPs formation, new disinfection processes and technologies were developed (e.g. ozone, ultraviolet, silver ion, electrochlorination, ferrate), involving high costs related to equipment and energy consumption (Mohd Zainudin et al., 2018). However, DBPs occurrence was demonstrated also for disinfection processes using non-chlorinated reagents (Ding et al., 2019).

Many members of the drinking water protection community have been actively working to clearly understand the possible negative effects of DBPs on human health. Meanwhile, state and federal governments have taken steps to protect the public from the potential health risks of DBPs by conducting research on their toxicological effects, strengthening drinking water regulations and supporting improvements in water treatment technology (Bereskie et al., 2017). Many authors focused their research on DBPs and disinfection processes under the following directions: (i) occurrence and removal of DBPs precursors deriving from raw water sources and optimization of DWT operational parameters and (ii) improved removal of DBPs and residual microorganisms at the end of DWT process and within the distribution network. Advanced drinking water treatment (ADWT) technologies are implemented for removing emerging pollutants (including DBPs) and reducing the concentrations of organic/inorganic precursors (Teodosiu et al., 2018).

This study has as main goal a consistent analysis of the major problems caused by emerging DBPs to drinking water supplies, providing a foundation for future research and highlighting the strengths and weaknesses of DBPs’ control processes. To our knowledge, most research focused so far on the identification of DBPs and their precursors rather than on removal technologies. This study has the aim to present a comprehensive review of the research efforts related to emerging DBPs considering three objectives: 1) an overview of their classification, legislative framework, methods of analysis, disinfection operational conditions and removal processes; 2) their occurrence, fate, health effects and impacts; 3) a critical assessment of the ADWT processes that might be used for the removal and control of emerging DBPs and their precursors, with a specific focus on pilot and full-scale installations.

Section snippets

Methodology

The analysis of the scientific literature considered for this review was based on the following selection criteria:

  • The relevance of articles and international information databases. This study was based on 207 documents: articles found in Science Direct, Scopus, Web of Science, Springer, Wiley Online Library, and reports downloaded from the European Commission or other international reference databases (165 scientific papers, 24 review papers, 18 books/technical reports/regulations);

  • Publication

Emerging DBPs of concern for drinking water treatment processes

DBPs are formed in drinking water from the reaction of disinfection agents with other compounds (precursors) occurring in raw water as: NOM, bromide and iodide, anthropogenic compounds (pharmaceuticals, antibacterial agents, textile dyes, pesticides, surfactants and cyanotoxins, etc.) (Papageorgiou et al., 2016; Richardson and Postigo, 2012). In recent years, great efforts were made to study the fate, occurrence and ecotoxicology of byproducts of drinking water disinfection processes. During

Advanced DWT technologies for DBPs prevention and control

Given the number of known DBPs and its continuous growth, to prevent their occurrence and development, operational parameters and drinking water characteristics should be carefully monitored. Implementing technologies that have the ability to remove DBPs and to prevent their re-emergence in the distribution network is highly necessary (López-Roldán et al., 2016). Conventional DWT processes needs to be completed with ADWT processes (Chaukura et al., 2020; Du et al., 2017; Ohar and Ostfeld, 2014)

Conclusions

DWT plants monitoring and management may not fully cover the regulated DBPs occurrence and further exposure of humans through drinking water consumption. DBPs and their precursors removal from treated water is the key to supply safe drinking water. Unlike the removal of commonly known precursors, which has been greatly developed, up-to-date treatment processes may not be efficient in removing emerging DBPs because of the lack of data on their trace concentrations and the risks associated with

Authors’ contributions

Conceptualization, methodology, supervision, writing-review & editing: C. Teodosiu and S. Fiore; data curation, investigation, writing-original draft: A.F. Gilca and C.P. Musteret.

Declaration of competing interest

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Acknowledgements

This work was supported by a grant of the Romanian Ministry of Research and Innovation, CCCDI-UEFISCDI, project number 26PCCDI/01.03.2018, “Integrated and sustainable processes for environmental clean-up, wastewater reuse and waste valorization” (SUSTENVPRO), within PNCDI III.

References (207)

  • R.S. Chaves et al.

    Hazard and mode of action of disinfection by-products (DBPs) in water for human consumption: evidences and research priorities

    Comp. Biochem. Physiol. C Toxicol. Pharmacol.

    (2019)
  • T.L. Chen et al.

    Rapid screening of haloacetamides in water using salt-assisted liquid-liquid extraction coupled injection-port silylation gas chromatography-mass spectrometry

    J. Chromatogr. A

    (2015)
  • W. Chen et al.

    Factors affecting the formation of nitrogenous disinfection by-products during chlorination of aspartic acid in drinking water

    Sci. Total Environ.

    (2017)
  • Y. Chen et al.

    The toxic potentials and focus of disinfection byproducts based on the human embryonic kidney (HEK293) cell model

    Sci. Total Environ.

    (2019)
  • R.K. Chhetri et al.

    Algal toxicity of the alternative disinfectants performic acid (PFA), peracetic acid (PAA), chlorine dioxide (ClO2) and their by-products hydrogen peroxide (H2O2) and chlorite (ClO2−)

    Int. J. Hyg Environ. Health

    (2017)
  • S. Chowdhury et al.

    Disinfection byproducts in Canadian provinces: associated cancer risks and medical expenses

    J. Hazard Mater.

    (2011)
  • W.H. Chu et al.

    Formation of nitrogenous disinfection by-products from pre-chloramination

    Chemosphere

    (2011)
  • W. Chu et al.

    Trace determination of 13 haloacetamides in drinking water using liquid chromatography triple quadrupole mass spectrometry with atmospheric pressure chemical ionization

    J. Chromatogr. A

    (2012)
  • S. Corbel et al.

    Cyanobacterial toxins: modes of actions, fate in aquatic and soil ecosystems, phytotoxicity and bioaccumulation in agricultural crops

    Chemosphere

    (2014)
  • G.A. de Vera et al.

    Kinetics and mechanisms of nitrate and ammonium formation during ozonation of dissolved organic nitrogen

    Water Res.

    (2017)
  • R. Delatolla et al.

    Disinfection byproduct formation during biofiltration cycle: implications for drinking water production

    Chemosphere

    (2015)
  • C. Di Cristo et al.

    Drinking water vulnerability assessment after disinfection through chlorine

    Procedia Eng

    (2015)
  • M. Diana et al.

    Disinfection byproducts potentially responsible for the association between chlorinated drinking water and bladder cancer: a review

    Water Res.

    (2019)
  • S. Ding et al.

    Recent advances in the analysis of nitrogenous disinfection by-products

    Trends Environ. Anal. Chem.

    (2017)
  • S. Ding et al.

    Disinfection byproduct formation during drinking water treatment and distribution: a review of unintended effects of engineering agents and materials

    Water Res.

    (2019)
  • L. Dongmei et al.

    Drinking water toxicity study of the environmental contaminant

    Bromate. Regul. Toxicol. Pharmacol.

    (2015)
  • Y. Du et al.

    Formation and control of disinfection byproducts and toxicity during reclaimed water chlorination: a review

    J. Environ. Sci.

    (2017)
  • M.S. Ersan et al.

    The control of N-nitrosodimethylamine, halonitromethane, and trihalomethane precursors by nanofiltration

    Water Res.

    (2016)
  • C.C. Fan et al.

    N-nitrosamines in drinking water and beer: detection and risk assessment

    Chemosphere

    (2018)
  • X. Fan et al.

    Performance of an integrated process combining ozonation with ceramic membrane ultra-filtration for advanced treatment of drinking water

    Desalination

    (2014)
  • D. Feretti et al.

    Evaluation of chlorite and chlorate genotoxicity using plant bioassays and in vitro DNA damage tests

    Water Res.

    (2008)
  • J. Fu et al.

    Removal of disinfection byproduct (DBP) precursors in water by two-stage biofiltration treatment

    Water Res.

    (2017)
  • R.J. Garcia-Villanova et al.

    Occurrence of bromate, chlorite and chlorate in drinking waters disinfected with hypochlorite reagents. Tracing their origins

    Sci. Total Environ.

    (2010)
  • K. Gopal et al.

    Chlorination byproducts, their toxicodynamics and removal from drinking water

    J. Hazard Mater.

    (2007)
  • E.H. Goslan et al.

    Carbonaceous and nitrogenous disinfection by-product formation from algal organic matter

    Chemosphere

    (2017)
  • S. Guilherme et al.

    Occurrence of regulated and non-regulated disinfection by-products in small drinking water systems

    Chemosphere

    (2014)
  • S. Guilherme et al.

    Short-term spatial and temporal variability of disinfection by-product occurrence in small drinking water systems

    Sci. Total Environ.

    (2015)
  • D. Hanigan et al.

    LC/QTOF-MS fragmentation of N-nitrosodimethylamine precursors in drinking water supplies is predictable and aids their identification

    J. Hazard Mater.

    (2017)
  • A. Hebert et al.

    Innovative method for prioritizing emerging disinfection by-products (DBPs) in drinking water on the basis of their potential impact on public health

    Water Res.

    (2010)
  • M.B. Heeb et al.

    Formation and reactivity of inorganic and organic chloramines and bromamines during oxidative water treatment

    Water Res.

    (2017)
  • B.E. Holmes et al.

    Identification of endocrine active disinfection by-products (DBPs) that bind to the androgen receptor

    Chemosphere

    (2017)
  • J. Hu et al.

    Comparison of drinking water treatment processes combinations for the minimization of subsequent disinfection by-products formation during chlorination and chloramination

    Chem. Eng. J.

    (2018)
  • S. Hu et al.

    Simultaneous determination of iodinated haloacetic acids and aromatic iodinated disinfection byproducts in waters with a new SPE-HPLC-MS/MS method

    Chemosphere

    (2018)
  • N. Huang et al.

    UV/chlorine as an advanced oxidation process for the degradation of benzalkonium chloride: synergistic effect, transformation products and toxicity evaluation

    Water Res.

    (2017)
  • S. Ileka-Priouzeau et al.

    Women exposure during pregnancy to haloacetaldehydes and haloacetonitriles in drinking water and risk of small-for-gestational-age neonate

    Environ. Res.

    (2015)
  • J.-Q. Jiang

    The Role of Ferrate(VI) in the remediation of emerging micro pollutants

    Procedia Environ. Sci.

    (2013)
  • Y. Jiang et al.

    Bromide oxidation by ferrate(VI): the formation of active bromine and bromate

    Water Res.

    (2016)
  • J. Jiang et al.

    A new approach to controlling halogenated DBPs by GAC adsorption of aromatic intermediates from chlorine disinfection: effects of bromide and contact time

    Separ. Purif. Technol.

    (2018)
  • R.R. Jones et al.

    Ingested nitrate, disinfection by-products, and risk of colon and rectal cancers in the Iowa Women’s Health Study cohort

    Environ. Int.

    (2019)
  • B. Jurado-Sánchez et al.

    Occurrence of carboxylic acids in different steps of two drinking-water treatment plants using different disinfectants

    Water Res.

    (2014)
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