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Reactions of Isocyanatoadamantanes with 3,6-Diazahomoadamantan-9-ylidene-substituted Hydrazines and Oximes

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Abstract

Carboxamides and carbamoyl oximes containing both adamantyl and 3,6-diazahomoadamantyl fragments were synthesized. The reactions proceed in mild conditions and in high yields. The synthesized compounds are promising as soluble epoxide hydrolase inhibitors.

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Funding

The work was financially supported by the Russian Foundation for Basic Research (project no. 19-33-60024).

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Authors and Affiliations

  1. University of Kerbala, 56001, Kerbala, Iraq

    R. T. Alasadi

  2. MIREA – Russian Technological University, Lomonosov Moscow Institute of Fine Chemical Technologies, 119571, Moscow, Russia

    R. T. Alasadi & A. I. Kuznetsov

  3. Volzhsky Polytechnic Institute Branch, Volgograd State Technical University, 404121, Volzhsky, Russia

    V. V. Burmistrov, D. A. Pitushkin & G. M. Butov

Authors
  1. R. T. Alasadi
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  2. V. V. Burmistrov
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  3. D. A. Pitushkin
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  4. A. I. Kuznetsov
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  5. G. M. Butov
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Corresponding author

Correspondence to G. M. Butov.

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The work is dedicated to the blessed memory of A.I. Kuznetsov

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Alasadi, R.T., Burmistrov, V.V., Pitushkin, D.A. et al. Reactions of Isocyanatoadamantanes with 3,6-Diazahomoadamantan-9-ylidene-substituted Hydrazines and Oximes. Russ J Org Chem 56, 729–734 (2020). https://doi.org/10.1134/S1070428020050012

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  • DOI: https://doi.org/10.1134/S1070428020050012

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