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NMR resonance assignments of the programmed cell death protein 5 (PDCD5) from Toxoplasma gondii

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Abstract

Toxoplasmosis is a systematic protozoan disease caused by a tiny parasite Toxoplasma gondii. The infection can be dangerous for pregnant woman and people with weak immune systems. The secreted protein named TgPDCD5 (Programmed cell death protein 5 from Toxoplasma gondii) plays an important role in apoptosis-inducing effect on host cells. Here, we report the 1H, 13C, and 15N resonance assignments of TgPDCD5. This work provides the ground for further structural elucidate and biophysical investigation about protein function.

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Acknowledgements

The NMR spectra were obtained at the High-field NMR Center, Academia Sinica (AS-CFII-108-112). This work is supported by National Taiwan University (NTU 108L7861 and NTU 109L7734) and the Ministry of Science and Technology, Taiwan (MOST 108-2113-M-002-011 and MOST 108-2628-B-002-013).

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Correspondence to Chun-Hua Hsu.

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Lin, MH., Yu, TA., Chang, CF. et al. NMR resonance assignments of the programmed cell death protein 5 (PDCD5) from Toxoplasma gondii. Biomol NMR Assign 14, 277–280 (2020). https://doi.org/10.1007/s12104-020-09961-8

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  • DOI: https://doi.org/10.1007/s12104-020-09961-8

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