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Ambulatory blood pressure abnormalities in children with migraine

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Abstract

Background

Although there are data showing that the frequency of hypertension increases in adults with migraine, there has been no study on this subject in children. In this study, we aimed to evaluate the presence of hypertension in children with migraine by performing ambulatory blood pressure monitoring (ABPM).

Methods

Thirty-seven children diagnosed with migraine and 30 healthy controls were evaluated between January 2015 and March 2016. Demographic data, clinical and laboratory features, and physical examination findings were recorded for both groups. Office blood pressure was measured for all children, and each also underwent ABPM. The two groups were compared in terms of ambulatory blood pressure parameters.

Results

The mean age was 13.3 and 13.1 years and the proportion of females was 73% and 60% in the migraine and control groups, respectively. Although the frequency of hypertension was not higher, abnormal ABPM patterns were found to be significantly more frequent in the migraine group (migraine, 45.9%; control, 16.7%; p, 0.018). Nighttime mean arterial blood pressure, nighttime diastolic blood pressure, and non-dipping pattern were higher in children with migraine than those in the control group (p < 0.05).

Conclusions

These results suggest that ambulatory blood pressure abnormalities may be present in almost half of patients with migraine. Therefore, we suggest that ABPM should be performed even if the office blood pressure measurements of children diagnosed with migraine are normal.

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Authors and Affiliations

  1. Department of Pediatric Nephrology, Ankara Yıldırım Beyazıt University Yenimahalle Education and Research Hospital, Ankara, Turkey

    Songül Yılmaz & Sare Gülfem Özlü

  2. Department of Pediatric Neurology, Ankara Yıldırım Beyazıt University Yenimahalle Education and Research Hospital, Ankara, Turkey

    Ayşegül Neşe Çıtak Kurt

Authors
  1. Songül Yılmaz
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  2. Sare Gülfem Özlü
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  3. Ayşegül Neşe Çıtak Kurt
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Correspondence to Songül Yılmaz.

Ethics declarations

The Research Ethics Committee of Ankara Yıldırım Beyazit University School of Medicine approved the study (date, 19 December 2016; number, 2016-10-04). Detailed information about the study was given to families of both study and control group patients, and written informed consent was obtained.

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This study was approved by the Research Ethics Committee of Ankara Yıldırım Beyazit University School of Medicine (date, 19 December 2016; number, 2016-10-04).

Children with CKD aged < 18 years were enrolled in this study after informed consent had been obtained from their parents or guardians.

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Yılmaz, S., Özlü, S.G. & Kurt, A.N.Ç. Ambulatory blood pressure abnormalities in children with migraine. Pediatr Nephrol 35, 2157–2162 (2020). https://doi.org/10.1007/s00467-020-04640-1

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  • DOI: https://doi.org/10.1007/s00467-020-04640-1

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