A systematic review and meta-analysis to investigate the concentration and prevalence of trichothecenes in the cereal-based food

doi:10.1016/j.tifs.2020.05.026

Trends in Food Science & Technology

Volume 102, August 2020, Pages 193-202

https://doi.org/10.1016/j.tifs.2020.05.026 Get rights and content

Highlights

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Fifty seven articles with 372 samples were included in our study.
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DON concentrations in cereal-based products were higher than other TCNs.
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The order of cereal-based food was breakfast cereals > noddle > bread > wheat foods > pasta > baby and infant foods > barley.
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The greatest TCNs incidence was observed for DON.

Abstract

Background

The contamination of food products by mycotoxin particularly trichothecenes is a serious health concern. While several studies investigated the concentration and prevalence of trichothecenes in cereal-based products, a comprehensive meta-analysis is not available.

Scope and approach

The concentration and prevalence of trichothecenes (TCNs) such as deoxynivalenol (DON), nivalenol (NIV), 3-acetyldeoxynivalen, 15-acetyldeoxynivalen, toxins T-2 and HT-2, neosolaniol (NEO), fusarenon-X and 4,15-diacetoxyscirpe in cereal-based food products among databases including Scopus, Web of Science, PubMed and Embase was investigated between 1 January of 1983 and 1 February of 2019 by the aid of a systematic review and meta-analysis prevalence. Among 950 explored articles in the identification stage, 57 articles with 372 samples were included in the current meta-analysis.

Key findings and conclusions

Among all studied TCNs, the concentration of DON in cereal-based products were higher than others, exceptionally in bread samples which fusurenon x was the dominant TCNs. Also, the highest TCNs prevalence was correlated with DON, except for baby and infant foods which had predominantly T-2. The overall rank order based on the concentration and prevalence of TCNs were breakfast cereals > noddle > bread > wheat foods > pasta > infant foods > barley prevalence and prevalence barley > wheat foods > infant foods > pasta > bread > breakfast cereals > noddle, respectively. The outcomes of the present meta-analysis highlighted the demand for further improvements in controlling of TCNs among cereal-based products, besides approaching mitigation techniques in order to reduce the dietary exposure to TCNs via the consumption of cereal-based foods.

Graphical abstract

Section snippets

1. introduction

Cereals and cereal-based products, such as maize, wheat, and barley, are used by most people in the world as their primary source of energy and nutrients (Lee & Ryu, 2017; Mishra, Ansari, Dwivedi, Pandey, & Das, 2013; Nematollahi et al., 2019). However, due to rich contents of protein, fat, and minerals, they are offering an excellent environment for fungi growth (Heshmati, Zohrevand, Khaneghah, Nejad, & Sant’Ana, 2017; Kyei, Boakye, & Gabrysch, 2020). Contamination of crops particularly

The protocol of the study

In the current study, a systematic review and meta-analysis were performed according to the Cochrane protocol (JPT Higgins & Wells, 2011). Screening of studies was carried out according to the PRISMA guideline (Fig. 1) (Liberati et al., 2009).

Search strategy

For performing the primary search, the main international databases including, Scopus, Web of Science, PubMed and Embase were screened to retrieve published studies regarding the concentration and prevalence of TCNs in cereal based foods from 1 January

Systematic review process

Among the citations published from 1 January 1983 and 1 February 2019, 950 articles were retrieved from main international databases including Scopus (n = 365), Web of Science (n = 121), PubMed (n = 253) and Embase (n = 211). In the identification step, 663 papers were excluded due to repetition. According to titles, 287 papers were recognized as potentially suitable, although 127 papers were excluded due to irrelevant content in the title. According to abstract, 160 papers were reviewed and 86

Conclusions

The present study is the first developed meta-analysis and systematic review considering the concentration and prevalence of TCNs (DON, NIV, 3-acetyldeoxynivalen, 15-acetyldeoxynivalen, T-2, HT-2, NEO, fusarenon-X and 4,15-diacetoxyscirpe) in cereal-based foods such as wheat-based products, pasta, noddle, breakfast cereals, baby and infant foods, bread, and barley as a systematic review and meta-analytic attempt. Our results showed that in all studied cereal-based products the DON concentration

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View full text

A systematic review and meta-analysis to investigate the concentration and prevalence of trichothecenes in the cereal-based food

Highlights

Abstract

Background

Scope and approach

Key findings and conclusions

Graphical abstract

Section snippets

1. introduction

The protocol of the study

Search strategy

Systematic review process

Conclusions

Acta Tropica

Journal of Chromatography A

Lebensmittel-Wissenschaft und -Technologie

Trends in Food Science and Technology

Food Control

Food Control

Journal of Food Composition and Analysis

Revista Iberoamericana De Micologia

Food Research International

Food Control

Food Chemistry

Lebensmittel-Wissenschaft und -Technologie

Food and Chemical Toxicology

Food Control

Food Control

Food Control

Food Chemistry

Food Control

Journal of Cereal Science

Food Control

Food Control

Food and Chemical Toxicology

Food and Chemical Toxicology

Journal of Food Composition and Analysis

Food and Chemical Toxicology

Food Chemistry

International Journal of Food Microbiology

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Occurrence of type A, B and D trichothecenes in barley and barley products from the Bavarian market

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