Original ArticleAlimentary TractClinical, Pathology, Genetic, and Molecular Features of Colorectal Tumors in Adolescents and Adults 25 Years or Younger
Alimentary Tract
Under a Creative Commons license
open access
Keywords
SCNA
Colon Cancer
MSI
MSS
Abbreviations used in this paper
AYA-CRC
children, adolescents, and young adults with colorectal cancer
CDX2
Caudal Type Homeobox 2
CK20
keratin 20
CMMRD
constitutional mismatch repair deficiency syndrome
CMS
consensus molecular subtypes
CRC
colorectal cancer
IBD
inflammatory bowel disease
IHC
immunohistochemistry
MMR
mismatch repair
MSI
microsatellite instability
MSS
microsatellite stable
NCR
The Netherlands Cancer Registry
NOS
not otherwise specified
PALGA
Nationwide network and registry of histo- and cytopathology
POLE-exo
POLE exonuclease domain
SCNA
somatic copy number alteration
smMIP
single-molecule molecular inversion probe
SRCC
signet ring cell carcinoma
TCGA
The Cancer Genome Atlas
Cited by (0)
Current address for M.C.J.J.: Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands, and Department of Clinical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
Conflicts of interest The authors disclose no conflicts.
Funding Supported by the Dutch Digestive Foundation FP13-19 (M.J.L.L.). The funding source had no role in the study design, conduct, data analysis and interpretation, or manuscript writing.
- a
Authors share co-first authorship.
© 2020 The Authors. Published by Elsevier Inc. on behalf of the AGA Institute.