Three new diterpenoid alkaloids, namely 1-N-deethyl-1,16-demethoxy-1,16-dihydroxy-N(19)-enaustroconitine A (1), 1-N-deethyl-1,16-demethoxy-1,16-dihydroxy-18-methoxy-N(19)-en-austroconitine A (2), and 1-N-deethyl-1,16-demethoxy-1,16-dihydroxyranaconidine (3), were isolated from the 80% ethanol extract of the roots of Aconitum iochanicum. Structural elucidation of all the compounds was performed by spectral methods such as 1D and 2D (1H–1H COSY, HMQC, and HMBC) NMR spectroscopy, in addition to high-resolution mass spectrometry.
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References
H. Niitsu, Y. Fujita, S. Fujita, R. Kumagai, M. Takamiya, Y. Aoki, and K. Dewa, Forensic Sci. Int., 227, 111 (2013).
J. Singhuber, M. Zhu, S. Prinz, and B. Kopp, J. Ethnopharmacol., 126, 18 (2009).
H. S. Abdillahi, J. F. Finnie, and J. Van Staden, J. Ethnopharmacol., 136, 496 (2011).
J. Li, W. Ren, X. J. Huang, D. J. Zou, and X. Hu, Brain Res. Bull., 97, 81 (2013).
T. Kiss, P. Orvos, S. Bansaghi, P. Forgo, N. Jedlinszki, L. Talosi, J. Hohmann, and D. Csupor, Fitoterapia, 90, 85 (2013).
M. Liang, S. C. Li, B. Shen, J. P. Cai, C. Li, Z. Y. Wang, X. G. Li, J. Gao, H. Y. Huang, X. Y. Zhang, and J. Y. Li, Carbohydr. Polym., 88, 973 (2012).
Y. L. Zhao, Q. Bu, Y. Zhou, L. Lv, G. Y. Yan, B. Chen, L. Wang, and X. B. Cen, NeuroToxicology, 31, 752 (2010).
R. Guo, C. X. Guo, D. He, D. K. Zhao, and Y. Shen, Chin. J. Chem., 35, 1644 (2017).
B. S. Joshi, S. K. Srivastava, A. D. Barber, H. K. Desai, and S. W. Pelletier, J. Nat. Prod., 60, 439 (1997).
J. G. Diaz, J. G. Ruiza, and W. Herz, Phytochemistry, 66, 837 (2005).
B. Xu, J. H. Xue, J. J. Tan, S. H. Jiang, F. J. Guo, and Y. M. Li, Helv. Chim. Acta, 97, 727 (2014).
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The above research was made possible by the grant from the joint special fund project of the Applied Basic Research for local university in Yunnan Province (2019FH001 (-033)), Special funds for reform and development of local university supported by the Central Finance (PL201707230369), and the National Undergraduate Training Programs for Innovation and Entrepreneurship (201910684029).
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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2020, pp. 424–426.
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Hu, J., Lv, Y., Li, Q. et al. Diterpenoid Alkaloids from the Roots of Aconitum iochanicum. Chem Nat Compd 56, 492–495 (2020). https://doi.org/10.1007/s10600-020-03069-0
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DOI: https://doi.org/10.1007/s10600-020-03069-0