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A New Sesquiterpene from Dendranthema grandiflora Flowers

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Chemistry of Natural Compounds Aims and scope

Chemical investigation of the dichloromethane extracts of the flowers of Dendranthema grandiflora cv. Yoko Ono afforded a new sesquiterpene lactone, grandiflorolide (1), 1,2-dilinoleoyl-3-linolenoylglycerol (2), a mixture of pseudotaraxasterol (3a), taraxasterol (3b), β-amyrin (3c), α-amyrin (3d), and lupeol (3e) in about 2:1:1:0.5:0.5 ratio, and another mixture of β-sitosterol (4a) and stigmasterol (4b) in about 2:1 ratio. The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy, while those of 2–4b were identified by comparison of their NMR data with literature data.

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Acknowledgment

A research grant from the De La Salle University Science Foundation, through the University Research Coordination Office, De La Salle University, Manila, Philippines, is gratefully acknowledged.

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Authors and Affiliations

  1. Chemistry Department, De La Salle University, 2401 Taft Avenue, 1004, Manila, Philippines

    Consolacion Y. Ragasa, Madeleine Si, Maria Carmen S. Tan & Deanne Hazel Pelobello

  2. Chemistry Department, De La Salle University Science & Technology Complex, Leandro V. Locsin Campus, 4024, Binan City, Laguna, Philippines

    Consolacion Y. Ragasa

  3. National Research Institute of Chinese Medicine, Ministry of Health and Welfare, 155-1, Li-Nong St., Sec. 2, Taipei, 112, Taiwan

    Ming-Jaw Don & Chien-Chang Shen

Authors
  1. Consolacion Y. Ragasa
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  2. Madeleine Si
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  3. Maria Carmen S. Tan
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  4. Deanne Hazel Pelobello
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  5. Ming-Jaw Don
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  6. Chien-Chang Shen
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Correspondence to Consolacion Y. Ragasa.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2020, pp. 378–380.

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Ragasa, C.Y., Si, M., Tan, M.C.S. et al. A New Sesquiterpene from Dendranthema grandiflora Flowers. Chem Nat Compd 56, 436–439 (2020). https://doi.org/10.1007/s10600-020-03057-4

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  • DOI: https://doi.org/10.1007/s10600-020-03057-4

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