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A Sesquiterpene Lactone from Irpex lacteus

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Chemistry of Natural Compounds Aims and scope

A new tremulane sesquiterpene lactone, named irlactin K (1), was isolated from the culture broth of the basidiomycete Irpex lacteus. The structure of the new compound was established through extensive spectroscopic analyses. The compound was tested for its cytotoxicity against five human cancer cell lines and for its inhibitory activity against isozymes of 11β-hydroxysteroid dehydrogenases.

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Acknowledgment

This project was supported by the Scientific Research Foundation of the Higher Education Institutions of Ningxia, China (NGY2018-107), the First-rate Discipline (Education) Construction Project of the Higher Education Institutions of Ningxia (NXYLXK2017B11), China, the Ningxia Normal University Research Grant (NXSFZDA1904), the Natural Science Foundation of Ningxia, China (2019AAC03245), the Key Research Foundation of Ningxia, China (2019BDE03009), the “Domestic Talent 312 Program” of Ningxia, China (NDB2018.1390, the Guyuan Science and Technology Support Program (2018GYYQ0007, 2019GKGY039), the National Natural Sciences Foundation of China (31760090), the Program for Innovation Talents of Science and Technology in Ningxia, China (KJT2015005), Youth talent cultivation Project in Ningxia, China (NXRS2017(279)), and Engineering and Technology Research Center the Guyan Talent Support Program (2019 GYSZZB1202) of Liupanshan Resources Grant (HGZD19-02), Ningxia Normal University, China.

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Correspondence to Jian-Hai Ding, Tao Feng or Ji-Kai Liu.

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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2020, pp. 350–352.

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Ding, JH., Li, ZH., Feng, T. et al. A Sesquiterpene Lactone from Irpex lacteus. Chem Nat Compd 56, 403–405 (2020). https://doi.org/10.1007/s10600-020-03047-6

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  • DOI: https://doi.org/10.1007/s10600-020-03047-6

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