Abstract
The resistance of a monolayer of complexes of the double-stranded DNA with quantum dots were computed. It was shown that with the non-competitive DNA hybridization and in the presence of monovalent positively charged ligands in the solution, a decrease in resistance occurs as compared to that for uncharged ligands. It is shown that the charged ligands enhance the sensitivity of the DNA chips as compared to the uncharged ones.
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Ivnitski, D., Abdel-Hamid, I., Atanasov, P., and Wilkins, E., Biosensors and Bioelectronics, 1999, vol. 14, p. 599.
Labuda, J., Brett, A.M.O., Evtugyn, G., Fojta, M., Mascini, M., Ozsoz, M., Palchetti, I., Paleček, E., and Wang, J., Pure Appl. Chem., 2010, vol. 82, p. 1161.
Watterson, J.H., Piunno, P.A.E., and Krull, U.J., Anal.Chem. Acta, 2002, vol. 457, p. 29.
Halperin, A., Buhot, A., and Zhulina, E.B., J. Phys.: Condens. Matter., 2006, vol. 18, p. S463.
Ananyan, G., Avetisyan, A., Aloyan, L., and Dalyan, Y., Biophys. Chem., 2011, vol. 156, p. 96.
Vardevanyan, P.O., Antonyan, A.P., Parsadanyan, M.A., and Shahinyan, M.A., J. Biomol. Struct. Dyn., DOI: https://doi.org/10.1080/07391102.2019.1630006 (2019).
Ghazaryan, A.A., Dalyan, Y.B., Haroutiunian, S.G., Tikhomirova, A., and Chalikian, T.V., J. Amer. Chem. Soc., 2006, vol. 128, p. 1914.
Pasternack, R.F., Goldsmith, J.I., Szep, S., and Gibbs, E.J., Biophys. J., 1998, vol. 75, p. 1024.
Willner, I., Patolsky, F., and Wasserman, J., Angew Chem. Int. Ed., 2001, vol. 40, p. 1861.
O’Neill, M.A. and Barton, J.K., J. Am. Chem. Soc., 2004, vol. 126, p. 11471.
Hinckley, D.M., Freeman, G.S., Whitmer, J.K., and de Pablo, J.J., J. Chem. Phys., 2013, vol. 139, p. 144903.
Hinckley, D.M., Lequieu, J.P., and de Pablo, J.J., J. Chem. Phys., 2014, vol. 141, p. 035102.
Peterson, A.W., Heaton, R.J., and Georgiadis, R.M., Nucl. Acids Res., 2001, vol. 29, p. 5163.
Halperin, A., Buhot, A., and Zhulina, E.B., Biophys. J., 2004, vol. 86, p. 718.
Hagan, M.F. and Chakraborty, A.K., J. Chem. Phys., 2004, vol. 120, p. 4958.
Seckar, M.M.A., Bloch, W., and John, P.M.S., Nucleic Acids Res., 2005, vol. 33, p. 366.
Sorokin, N.V., Chechetkin, V.R., Pan’kov, S.V., Somova, O.G., Livshits, M.A., Donnikov, M.Y., Turygin, A.Y., Barsky, V.E., and Zasedatelev, A.S., J. Biomol. Struct. Dyn., 2006, vol. 24, p. 57.
Irving, D., Gong, P., and Levicky, R., J. Phys. Chem. B, 2010, vol. 114, p. 7631.
Schmitt, T.J. and Knotts IV, T.A., J. Chem. Phys., 2011, vol. 134, p. 205105.
Nelson, S.M., Ferguson, L.R., and Denny, W.A., Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2007, vol. 623, p. 24.
Kostjukov, V.V., Santiago, A.A.H., Rodriguez, F.R., Castilla, S.R., Parkinson, J.A., and Evstigneev, M.P., Phys. Chem. Chem. Phys., 2012, vol. 14, p. 5588.
Ricci, C.G. and Netz, P.A., J. Chem. Inf. Model., 2009, vol. 49, p. 1925.
Ba, D. and Boyaci, I.H., Anal. Bioanal. Chem., 2011, vol. 400, p. 703.
Xiang, L., Palma, J.L., Bruot, C., Mujica, V., Ratner, M.A., and Tao, N., Nature Chem., 7(3), 221 (2015).
Tonoyan, Sh.A., Hakobyan, A.A., Andreassian, A.K., Morozov, V.F., and Mamasakhlisov, Y.Sh., J. Contemp. Phys. (Armenian Ac. Sci.), 2018, vol. 53, p. 179.
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Russian Text © The Author(s), 2020, published in Izvestiya Natsional’noi Akademii Nauk Armenii, Fizika, 2020, Vol. 55, No. 1, pp. 117–125.
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Mamasakhlisov, A.Y., Kazaryan, E.M., Tonoyan, S.A. et al. The Conductivity of the Monolayer of DNA — Quantum Dot Complexes in the Presence of Intercalating Charged Ligands. J. Contemp. Phys. 55, 87–93 (2020). https://doi.org/10.3103/S1068337220010120
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DOI: https://doi.org/10.3103/S1068337220010120