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Synthesis and Modification of Hetero-Fused Pyrazoles Derived from Methyl 1-(2-Oxo-2-phenylethyl)-3-phenyl-1H-pyrazole-5-carboxylate

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Abstract

A modified procedure has been proposed for the synthesis of 2,7-diphenyl-5,8-dihydro-4H-pyrazolo[5,1-d][1,2,5]triazepin-4-one, and the possibility of transformation of the latter to the pyrazolo[1,5-a]pyrazine system has been demonstrated. Functionalization of 2,7-diphenyl-5,8-dihydro-4H-pyrazolo[5,1-d][1,2,5]triazepin-4-one at the 4-position and fusion of a tetrazole or triazole ring at the C4–N5 bond have been performed.

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  1. Litvinenko Institute of Physical Organic and Coal Chemistry, 83114, Donetsk, Ukraine

    A. O. Kharaneko, T. M. Pekhtereva & O. I. Kharaneko

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  1. A. O. Kharaneko
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  2. T. M. Pekhtereva
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  3. O. I. Kharaneko
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Correspondence to O. I. Kharaneko.

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Kharaneko, A.O., Pekhtereva, T.M. & Kharaneko, O.I. Synthesis and Modification of Hetero-Fused Pyrazoles Derived from Methyl 1-(2-Oxo-2-phenylethyl)-3-phenyl-1H-pyrazole-5-carboxylate. Russ J Org Chem 56, 654–661 (2020). https://doi.org/10.1134/S1070428020040144

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  • DOI: https://doi.org/10.1134/S1070428020040144

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