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Chemisorption of Glycidyl Spacer on Magnetic Nanoparticles and Immobilization of Albumin and Quinacrine

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Abstract

Chemisorption of a glycidyl spacer on the surface of magnetic nanoparticles from three solvents has been performed. It has been shown that the chemisorption from benzene is the most efficient. Human albumin and quinacrine as a model pharmaceutical have been immobilized via a glycidyl spacer. A mechanism of the interaction of albumin and quinacrine with glycidyl groups has been suggested.

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Funding

This study was performed using the equipment of Resource Centers of St. Petersburg State University: “Optical and Laser Methods of Investigation” and “Innovative Technologies in Composite Nanomaterials.”

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Correspondence to G. A. Shulmeyster.

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Korolev, D.V., Postnov, V.N., Romanova, T.N. et al. Chemisorption of Glycidyl Spacer on Magnetic Nanoparticles and Immobilization of Albumin and Quinacrine. Russ J Gen Chem 90, 398–403 (2020). https://doi.org/10.1134/S1070363220030111

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  • DOI: https://doi.org/10.1134/S1070363220030111

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