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Licensed Unlicensed Requires Authentication Published by De Gruyter March 17, 2020

Beryllium-associated diseases from a chemist’s point of view

  • Magnus R. Buchner EMAIL logo

Abstract

Beryllium has long been considered the most toxic non-radioactive element to humans. However, it is shown that the acute toxicity of beryllium ions does not exceed that of other toxic cations like Cd2+, Ba2+, Hg2+ or As3+. The physiological mechanisms liable for the development of beryllium-associated diseases are discussed. Additionally an overview over proposed low-molecular model system for the beryllium species responsible for beryllioses is presented.

Acknowledgement

The author thanks Prof. Florian Kraus for moral and financial support as wells as the provision of laboratory space and input on the manuscript. For the latter MRB is also grateful to Jasmin Schönzart, Matthias Müller, Nils Spang and H. Lars Deubner. Prof. Rainer Pöttgen is thanked for his enthusiasm regarding beryllium chemistry and for encouraging this article. The DFG is gratefully acknowledged for financial support (BU2725/8-1).

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Received: 2020-01-15
Accepted: 2020-02-29
Published Online: 2020-03-17
Published in Print: 2020-05-26

©2020 Walter de Gruyter GmbH, Berlin/Boston

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