Issue 12, 2020
From the journal:

Organic Chemistry Frontiers

Aromatization-driven deconstruction/refunctionalization of unstrained rings

Fangzhi Hu, ORCID logo a   Liang Wang, ORCID logo ab   Lubin Xua  and  Shuai-Shuai Li ORCID logo *ab  

* Corresponding authors

a College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao 266109, China
E-mail: flyshuaishuai@126.com

b College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Zhengzhou Rd. #53, Qingdao 266042, P. R. China

Abstract

Aromatization-driven ring-opening/functionalization of common unstrained rings has been developed with the in situ generation of pre-aromatic fused spiro heterocycles as the key step, featuring (1) simple operation via a convenient one-pot reaction and (2) broad scope of various ring systems which do not require pre-activation.

Graphical abstract: Aromatization-driven deconstruction/refunctionalization of unstrained rings

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Article information

DOI
https://doi.org/10.1039/D0QO00344A
Article type
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Submitted
19 Mar 2020
Accepted
22 May 2020
First published
01 Jun 2020

Org. Chem. Front., 2020,7, 1570-1575

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Aromatization-driven deconstruction/refunctionalization of unstrained rings

F. Hu, L. Wang, L. Xu and S. Li, Org. Chem. Front., 2020, 7, 1570 DOI: 10.1039/D0QO00344A

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