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Annual Review of Plant Biology

Volume 71, 2020

The Small GTPase Superfamily in Plants: A Conserved Regulatory Module with Novel Functions

Abstract

Small GTP-binding proteins represent a highly conserved signaling module in eukaryotes that regulates diverse cellular processes such as signal transduction, cytoskeletal organization and cell polarity, cell proliferation and differentiation, intracellular membrane trafficking and transport vesicle formation, and nucleocytoplasmic transport. These proteins function as molecular switches that cycle between active and inactive states, and this cycle is linked to GTP binding and hydrolysis. In this review, the roles of the plant complement of small GTP-binding proteins in these cellular processes are described, as well as accessory proteins that control their activity, and current understanding of the functions of individual members of these families in plants—with a focus on the model organism —is presented. Some potential novel roles of these GTPases in plants, relative to their established roles in yeast and/or animal systems, are also discussed.

Keyword(s): Arf, membrane trafficking, nuclear import, Rab, Ran, Rop, small GTPase, vesicle transport
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/content/journals/10.1146/annurev-arplant-112619-025827
2020-04-29
2024-04-18
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The Small GTPase Superfamily in Plants: A Conserved Regulatory Module with Novel Functions
Annual Review of Plant Biology 71, 247 (2020); https://doi.org/10.1146/annurev-arplant-112619-025827
/content/journals/10.1146/annurev-arplant-112619-025827
/content/journals/10.1146/annurev-arplant-112619-025827
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