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Genomic diversity and recombination of Seneca Valley viruses emerged in pig herds in Guangdong Province during 2019

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Abstract

Seneca Valley virus (SVV) is an emerging global picornavirus that causes porcine idiopathic vesicular disease. We characterized the genome and conducted evolutionary and recombination analyses of four newly identified SVV strains which were CH-GDZS-2019, CH-GDMZ-2019, CH-GDHZ01-2019, and CH-GDHZ02-2019. Sequence alignment and phylogenetic analysis showed that strains circulating in swine herds in China were genetically diverse and complex. Recombination analyses indicated that strain CH-GDZS-2019 was derived from strains USA-IA44662-2015-P1 and USA-GBI29-2015, which were both isolated in the USA in 2015, while CH-GDMZ-2019 was derived from the Chinese field strains 1-2018-BH-China and CH-GDQC-2017. Our results provided important insights into the molecular characterization of the SVV strains co-circulating in Guangdong Province in China in 2019 and demonstrated the importance of additional SVV surveillance in China.

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Acknowledgements

This work was supported by the Natural Science Foundation of Guangdong Province (2019A1515011735).

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Authors and Affiliations

  1. College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China

    Jianxin Liu, Qianju Guo, Huizi Li, Xianglong Yu, Boyang Liu, Bingqian Zhao & Zhangyong Ning

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  1. Jianxin Liu
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  2. Qianju Guo
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  3. Huizi Li
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  4. Xianglong Yu
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  5. Boyang Liu
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  6. Bingqian Zhao
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  7. Zhangyong Ning
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Contributions

JL and ZN conceived the experiments and wrote the manuscript. JL, QG, HL, and XY performed all the experiments. JL, QG, BL, and BZ analyzed the data. All authors have given approval to the final version of the manuscript.

Corresponding author

Correspondence to Zhangyong Ning.

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The authors declare that there are no conflicts of interest.

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All applicable international, national, and/or institutional guidelines for the care and use of animals were followed.

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Edited by Takeshi Noda.

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Liu, J., Guo, Q., Li, H. et al. Genomic diversity and recombination of Seneca Valley viruses emerged in pig herds in Guangdong Province during 2019. Virus Genes 56, 642–645 (2020). https://doi.org/10.1007/s11262-020-01769-x

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  • DOI: https://doi.org/10.1007/s11262-020-01769-x

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