The discovery of selective modulators of two Cryptochrome isoforms, CRY1 and CRY2, permits a deeper understanding of how circadian clock proteins impact diverse aspects of our daily 24-h rhythms and how this intersects with metabolic pathways relevant to disease.
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Lara, J., Zoltowski, B.D. A tail of CRY selectivity. Nat Chem Biol 16, 608–609 (2020). https://doi.org/10.1038/s41589-020-0531-z
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DOI: https://doi.org/10.1038/s41589-020-0531-z
