Abstract
Since the addition of polybrominated diphenyls and organochlorine pesticides (OCPs) to the world banned list, toxic organophosphate contaminants (OPCs) such as organophosphate flame retardants and organophosphate pesticides have been, respectively, used as substitutes. These chemicals are reported to be more toxic than their halogenated counterparts. It is rare to find a study that focuses on visualising the publication trends of these chemical classes. In this study, we employed a bibliometric model to systematically map research activities between 1990 and 2018 using OPC articles retrieved from the WoS and Scopus databases. A total of 1090 articles were retrieved from the hybrid databases with an article/author and author/article ratio of 0.33 and 3.02, respectively. Articles on OPC studies were positively correlated with the number of years (r2 = 0.96; y = 0.23x2 − 3.82x + 27.90) suggesting an increase in the number of articles on this subject in future. The USA ranked first in terms of articles (n = 245) and citations (n = 12,922) followed by China and India (203 and 89 articles, respectively). Articles from China and the USA had strong collaboration with other countries. Research priorities and top author keywords included pesticides (n = 112), organophosphate (n = 83) and acetylcholinesterase (n = 60) and were also well represented in keywords-plus. Developed countries had higher outputs compared to developing countries. It was observed that from our thematic literature classifications, human toxicity, ecotoxicological impacts, and environmental monitoring of OPCs were of greater importance to scholars, thus indicating the direction of future research. Futuristic studies need to foster partnership with policymakers, journalists, consultants, farmers, artisans and community workers on OPC research. This will not only enhance scientific communication and community engagement but will also increase the awareness of these pollutants to the general public.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Abou-Elwafa Abdallah, M., Pawar, G., & Harrad, S. (2016). Human dermal absorption of chlorinated organophosphate flame retardants; implications for human exposure. Toxicology and Applied Pharmacology. https://doi.org/10.1016/j.taap.2015.12.004.
Abuelmaali, S. A., Elaagip, A. H., Basheer, M. A., Frah, E. A., Ahmed, F. T. A., Elhaj, H. F. A., et al. (2013). Impacts of agricultural practices on insecticide resistance in the malaria vector Anopheles arabiensis in Khartoum state, Sudan. PLoS ONE. https://doi.org/10.1371/journal.pone.0080549.
Aghaei Chadegani, A., Salehi, H., Md Yunus, M. M., Farhadi, H., Fooladi, M., Farhadi, M., et al. (2013). A comparison between two main academic literature collections: Web of science and scopus databases. Asian Social Science. https://doi.org/10.5539/ass.v9n5p18.
Akbel, E., Arslan-Acaroz, D., Demirel, H. H., Kucukkurt, I., & Ince, S. (2018). The subchronic exposure to malathion, an organophosphate pesticide, causes lipid peroxidation, oxidative stress, and tissue damage in rats: The protective role of resveratrol. Toxicology Research. https://doi.org/10.1039/c8tx00030a.
Ali, N., Ibrahim Ismail, I. M., Kadi, M. W., & Salem Ali Albar, H. M. (2018). Currently used organophosphate flame retardants determined in the settled dust of masjids and hotels of Saudi Arabia, a new insight into human health implications of dust exposure. Environmental Science: Processes and Impacts. https://doi.org/10.1039/c8em00014j.
Alves, A., Covaci, A., & Voorspoels, S. (2017). Method development for assessing the human exposure to organophosphate flame retardants in hair and nails. Chemosphere. https://doi.org/10.1016/j.chemosphere.2016.11.006.
Antonopoulou, M., Giannakas, A., Bairamis, F., Papadaki, M., & Konstantinou, I. (2017). Degradation of organophosphorus flame retardant tris (1-chloro-2-propyl) phosphate (TCPP) by visible light N, S-codoped TiO2 photocatalysts. Chemical Engineering Journal. https://doi.org/10.1016/j.cej.2016.06.124.
Aria, M., & Cuccurullo, C. (2017). bibliometrix: An R-tool for comprehensive science mapping analysis. Journal of Informetrics. https://doi.org/10.1016/j.joi.2017.08.007.
Babina, K., Dollard, M., Pilotto, L., & Edwards, J. W. (2012). Environmental exposure to organophosphorus and pyrethroid pesticides in South Australian preschool children: A cross sectional study. Environment International. https://doi.org/10.1016/j.envint.2012.07.007.
Balme, K., McCulloch, M., & Stephen, C. (2018). Prolonged paralysis in a child with organophosphate pesticide poisoning. South African Medical Journal. https://doi.org/10.7196/samj.2018.v108i6.12994.
Bello, A., Carignan, C. C., Xue, Y., Stapleton, H. M., & Bello, D. (2018). Exposure to organophosphate flame retardants in spray polyurethane foam applicators: Role of dermal exposure. Environment International. https://doi.org/10.1016/j.envint.2018.01.020.
Boada, L. D., Sangil, M., Álvarez-León, E. E., Hernández-Rodríguez, G., Henríquez-Hernández, L. A., Camacho, M., et al. (2014). Consumption of foods of animal origin as determinant of contamination by organochlorine pesticides and polychlorobiphenyls: Results from a population-based study in Spain. Chemosphere. https://doi.org/10.1016/j.chemosphere.2014.03.126.
Bouchard, M. F., Bellinger, D. C., Wright, R. O., & Weisskopf, M. G. (2010). Attention-deficit/hyperactivity disorder and urinary metabolites of organophosphate pesticides. Pediatrics. https://doi.org/10.1542/peds.2009-3058.
Bouchard, M. F., Chevrier, J., Harley, K. G., Kogut, K., Vedar, M., Calderon, N., et al. (2011). Prenatal exposure to organophosphate pesticides and IQ in 7-year-old children. Environmental Health Perspectives. https://doi.org/10.1289/ehp.1003185.
Bozeman, B., Fay, D., & Slade, C. P. (2013). Research collaboration in universities and academic entrepreneurship: The-state-of-the-art. Journal of Technology Transfer. https://doi.org/10.1007/s10961-012-9281-8.
Bukvova, H. (2010). Studying research collaboration: A literature review. Sprouts: Working papers on information systems.
Butt, C. M., Congleton, J., Hoffman, K., Fang, M., & Stapleton, H. M. (2014). Metabolites of organophosphate flame retardants and 2-ethylhexyl tetrabromobenzoate in urine from paired mothers and toddlers. Environmental Science and Technology. https://doi.org/10.1021/es5025299.
Butt, C. M., Hoffman, K., Chen, A., Lorenzo, A., Congleton, J., & Stapleton, H. M. (2016). Regional comparison of organophosphate flame retardant (PFR) urinary metabolites and tetrabromobenzoic acid (TBBA) in mother-toddler pairs from California and New Jersey. Environment International. https://doi.org/10.1016/j.envint.2016.06.029.
Cañas-Guerrero, I., Mazarrón, F. R., Pou-Merina, A., Calleja-Perucho, C., & Díaz-Rubio, G. (2013). Bibliometric analysis of research activity in the “Agronomy” category from the Web of Science, 1997–2011. European Journal of Agronomy. https://doi.org/10.1016/j.eja.2013.05.002.
Cao, S., Zeng, X., Song, H., Li, H., Yu, Z., Sheng, G., et al. (2012). Levels and distributions of organophosphate flame retardants and plasticizers in sediment from Taihu Lake, China. Environmental Toxicology and Chemistry, 8, 8–9. https://doi.org/10.1002/etc.1872.
Carignan, C. C., Mínguez-Alarcón, L., Williams, P. L., Meeker, J. D., Stapleton, H. M., Butt, C. M., et al. (2018). Paternal urinary concentrations of organophosphate flame retardant metabolites, fertility measures, and pregnancy outcomes among couples undergoing in vitro fertilization. Environment International. https://doi.org/10.1016/j.envint.2017.12.005.
Chang, C. H., Yu, C. J., Du, J. C., Chiou, H. C., Chen, H. C., Yang, W., et al. (2018). The interactions among organophosphate pesticide exposure, oxidative stress, and genetic polymorphisms of dopamine receptor D4 increase the risk of attention deficit/hyperactivity disorder in children. Environmental Research. https://doi.org/10.1016/j.envres.2017.10.011.
Cheek, J., Garnham, B., & Quan, J. (2006). What’s in a number? Issues in providing evidence of impact and quality of research(ers). Qualitative Health Research. https://doi.org/10.1177/1049732305285701.
Chen, R., Hou, R., Hong, X., Yan, S., & Zha, J. (2019). Organophosphate flame retardants (OPFRs) induce genotoxicity in vivo: A survey on apoptosis, DNA methylation, DNA oxidative damage, liver metabolites, and transcriptomics. Environment International. https://doi.org/10.1016/j.envint.2019.104914.
Chu, S., Baker, M. R., Leong, G., Letcher, R. J., Gee, S. J., Hammock, B. D., et al. (2017). Exploring adduct formation between human serum albumin and eleven organophosphate ester flame retardants and plasticizers using MALDI-TOF/TOF and LC-Q/TOF. Chemosphere. https://doi.org/10.1016/j.chemosphere.2017.03.124.
Creasey, S. (2007). How going green helps you clean up. Printing World, 66–68.
Cui, K., Wen, J., Zeng, F., Zhou, X., Li, S., & Zeng, Z. (2017). Determination of organophosphate ester flame retardants and plasticizers in soil samples by microwave-assisted extraction coupled with silica gel/alumina multilayer solid-phase extraction and gas chromatography-mass spectrometry. Analytical Methods. https://doi.org/10.1039/c6ay02837c.
Cui, H. F., Wu, W. W., Li, M. M., Song, X., Lv, Y., & Zhang, T. T. (2018). A highly stable acetylcholinesterase biosensor based on chitosan-TiO2-graphene nanocomposites for detection of organophosphate pesticides. Biosensors & Bioelectronics. https://doi.org/10.1016/j.bios.2017.07.068.
Cunha, L. S. T., Torres, J. P. M., Muñoz-Arnanz, J., & Jiménez, B. (2012). Evaluation of the possible adverse effects of legacy persistent organic pollutants (POPs) on the brown booby (Sula leucogaster) along the Brazilian coast. Chemosphere. https://doi.org/10.1016/j.chemosphere.2012.02.009.
Deo, R. P., Wang, J., Block, I., Mulchandani, A., Joshi, K. A., Trojanowicz, M., et al. (2005). Determination of organophosphate pesticides at a carbon nanotube/organophosphorus hydrolase electrochemical biosensor. Analytica Chimica Acta. https://doi.org/10.1016/j.aca.2004.09.072.
Dhital, S., & Rupakheti, D. (2019). Bibliometric analysis of global research on air pollution and human health: 1998–2017. Environmental Science and Pollution Research, 26(13), 13103–13114. https://doi.org/10.1007/s11356-019-04482-x.
Ding, J., Xu, Z., Huang, W., Feng, L., & Yang, F. (2016). Organophosphate ester flame retardants and plasticizers in human placenta in Eastern China. Science of the Total Environment. https://doi.org/10.1016/j.scitotenv.2016.02.171.
Elham, R., Ebrahim, T. K., Leila, K., Farzad, P., Nazanin, S. J., Mohammad, P., et al. (2015). The effect of herbicide paraquat and organophosphate pesticide malathion on changes of sex hormones in female rats. Biomedical and Pharmacology Journal. https://doi.org/10.13005/bpj/851.
Eskenazi, B., Bradman, A., & Castorina, R. (1999). Exposures of children to organophosphate pesticides and their potential adverse health effects. Environmental Health Perspectives. https://doi.org/10.1289/ehp.99107s3409.
Eskenazi, B., Harley, K., Bradman, A., Weltzien, E., Jewell, N. P., Barr, D. B., et al. (2004). Association of in utero organophosphate pesticide exposure and fetal growth and length of gestation in an agricultural population. Environmental Health Perspectives. https://doi.org/10.1289/ehp.6789.
Eskenazi, B., Marks, A. R., Bradman, A., Harley, K., Barr, D. B., Johnson, C., et al. (2007). Organophosphate pesticide exposure and neurodevelopment in young Mexican-American children. Environmental Health Perspectives. https://doi.org/10.1289/ehp.9828.
Faggion, C. M., Málaga, L., Monje, A., Trescher, A. L., Listl, S., & Alarcón, M. A. (2017). The 300 most cited articles published in periodontology. Clinical Oral Investigations. https://doi.org/10.1007/s00784-016-1990-1.
Fahimnia, B., Sarkis, J., & Davarzani, H. (2015). Green supply chain management: A review and bibliometric analysis. International Journal of Production Economics, 162, 101–114. https://doi.org/10.1016/j.ijpe.2015.01.003.
Fardi, A., Kodonas, K., Gogos, C., & Economides, N. (2011). Top-cited articles in endodontic journals. Journal of Endodontics. https://doi.org/10.1016/j.joen.2011.05.037.
Feijoo, J. F., Limeres, J., Fernández-Varela, M., Ramos, I., & Diz, P. (2014). The 100 most cited articles in dentistry. Clinical Oral Investigations. https://doi.org/10.1007/s00784-013-1017-0.
Feng, L., Ouyang, F., Liu, L., Wang, X., Wang, X., Li, Y. J., et al. (2016). Levels of urinary metabolites of organophosphate flame retardants, TDCIPP, and TPHP, in pregnant women in Shanghai. Journal of Environmental and Public Health. https://doi.org/10.1155/2016/9416054.
Fu, L., Du, B., Wang, F., Lam, J. C. W., Zeng, L., & Zeng, E. Y. (2017). Organophosphate triesters and diester degradation products in municipal sludge from wastewater treatment plants in China: Spatial patterns and ecological implications. Environmental Science and Technology. https://doi.org/10.1021/acs.est.7b04106.
Furlong, M. A., Engel, S. M., Barr, D. B., & Wolff, M. S. (2014). Prenatal exposure to organophosphate pesticides and reciprocal social behavior in childhood. Environment International. https://doi.org/10.1016/j.envint.2014.05.011.
Garg, U. K., Pal, A. K., Jha, G. J., & Jadhao, S. B. (2004). Haemato-biochemical and immuno-pathophysiological effects of chronic toxicity with synthetic pyrethroid, organophosphate and chlorinated pesticides in broiler chicks. International Immunopharmacology. https://doi.org/10.1016/j.intimp.2004.08.002.
Glass, T., Dalvie, M. A., Holtman, Z., Vorster, A. A., Ramesar, R. S., & London, L. (2018). DNA variants and organophosphate neurotoxicity among emerging farmers in the Western Cape of South Africa. American Journal of Industrial Medicine. https://doi.org/10.1002/ajim.22790.
Gu, J., Su, F., Hong, P. P., Zhang, Q., & Zhao, M. (2019). 1 H NMR-based metabolomic analysis of nine organophosphate flame retardants metabolic disturbance in Hep G2 cell line. Science of the Total Environment. https://doi.org/10.1016/j.scitotenv.2019.02.055.
Guo, J., Venier, M., Salamova, A., & Hites, R. A. (2017). Bioaccumulation of Dechloranes, organophosphate esters, and other flame retardants in Great Lakes fish. Science of the Total Environment. https://doi.org/10.1016/j.scitotenv.2016.11.063.
Hazarika, R. (2014). Neurotoxic impact of organophosphate pesticide phosphomedon on the albino rat. Journal of Environmental Biology, 35, 427.
Hoffman, K., Daniels, J. L., & Stapleton, H. M. (2014). Urinary metabolites of organophosphate flame retardants and their variability in pregnant women. Environment International. https://doi.org/10.1016/j.envint.2013.11.013.
Hossaini, H., Moussavi, G., & Farrokhi, M. (2014). The investigation of the LED-activated FeFNS-TiO2 nanocatalyst for photocatalytic degradation and mineralization of organophosphate pesticides in water. Water Research. https://doi.org/10.1016/j.watres.2014.04.009.
Hou, R., Xu, Y., & Wang, Z. (2016). Review of OPFRs in animals and humans: Absorption, bioaccumulation, metabolism, and internal exposure research. Chemosphere. https://doi.org/10.1016/j.chemosphere.2016.03.003.
How, V., Hashim, Z., Ismail, P., Md Said, S., Omar, D., & Bahri Mohd Tamrin, S. (2014). Exploring cancer development in adulthood: Cholinesterase depression and genotoxic effect from chronic exposure to organophosphate pesticides among rural farm children. Journal of Agromedicine, 19(1), 35–43. https://doi.org/10.1080/1059924x.2013.866917.
Howe, K., Clark, M. D., Torroja, C. F., Torrance, J., Berthelot, C., Muffato, M., et al. (2013). The zebrafish reference genome sequence and its relationship to the human genome. Nature. https://doi.org/10.1038/nature12111.
Hu, L., Luo, D., Zhou, T., Tao, Y., Feng, J., & Mei, S. (2017). The association between non-Hodgkin lymphoma and organophosphate pesticides exposure: A meta-analysis. Environmental Pollution. https://doi.org/10.1016/j.envpol.2017.08.028.
Jaipieam, S., Visuthismajarn, P., Sutheravut, P., Siriwong, W., Thoumsang, S., Borjan, M., et al. (2009). Organophosphate pesticide residues in drinking water from artesian wells and health risk assessment of agricultural communities, Thailand. Human and Ecological Risk Assessment, 8, 8–9. https://doi.org/10.1080/10807030903306984.
Jeong, S., Choi, J. Y., & Kim, J. (2011). The determinants of research collaboration modes: Exploring the effects of research and researcher characteristics on co-authorship. Scientometrics. https://doi.org/10.1007/s11192-011-0474-y.
Joshi, S. C., Mathur, R., & Gulati, N. (2007). Testicular toxicity of chlorpyrifos (an organophosphate pesticide) in albino rat. Toxicology and Industrial Health. https://doi.org/10.1177/0748233707080908.
Kalueff, A. V., Stewart, A. M., & Gerlai, R. (2014). Zebrafish as an emerging model for studying complex brain disorders. Trends in Pharmacological Sciences. https://doi.org/10.1016/j.tips.2013.12.002.
Kemmlein, S., Hahn, O., & Jann, O. (2003). Emissions of organophosphate and brominated flame retardants from selected consumer products and building materials. Atmospheric Environment. https://doi.org/10.1016/j.atmosenv.2003.09.025.
Khairy, M. A., & Lohmann, R. (2019). Organophosphate flame retardants in the indoor and outdoor dust and gas-phase of Alexandria, Egypt. Chemosphere. https://doi.org/10.1016/j.chemosphere.2018.12.140.
Kim, U. J., & Kannan, K. (2018). Occurrence and distribution of organophosphate flame retardants/plasticizers in surface waters, tap water, and rainwater: Implications for human exposure. Environmental Science and Technology. https://doi.org/10.1021/acs.est.8b00727.
Kongtip, P., Techasaensiri, B., Nankongnab, N., Adams, J., Phamonphon, A., Surach, A., et al. (2017). The impact of prenatal organophosphate pesticide exposures on thai infant neurodevelopment. International Journal of Environmental Research and Public Health. https://doi.org/10.3390/ijerph14060570.
Kostoff, R. N., Briggs, M. B., Rushenberg, R. L., Bowles, C. A., Icenhour, A. S., Nikodym, K. F., et al. (2007). Chinese science and technology—Structure and infrastructure. Technological Forecasting and Social Change. https://doi.org/10.1016/j.techfore.2007.02.008.
Krumm, E. A., Patel, V. J., Tillery, T. S., Yasrebi, A., Shen, J., Guo, G. L., et al. (2018). Organophosphate flame-retardants alter adult mouse homeostasis and gene expression in a sex-dependent manner potentially through interactions with ERα. Toxicological Sciences: An Official Journal of the Society of Toxicology. https://doi.org/10.1093/toxsci/kfx238.
Krzeminski, P., Schwermer, C., Wennberg, A., Langford, K., & Vogelsang, C. (2017). Occurrence of UV filters, fragrances and organophosphate flame retardants in municipal WWTP effluents and their removal during membrane post-treatment. Journal of Hazardous Materials. https://doi.org/10.1016/j.jhazmat.2016.08.001.
Kwong, T. C. (2002). Organophosphate pesticides: Biochemistry and clinical toxicology. Therapeutic Drug Monitoring. https://doi.org/10.1097/00007691-200202000-00022.
Lang, Q., Han, L., Hou, C., Wang, F., & Liu, A. (2016). A sensitive acetylcholinesterase biosensor based on gold nanorods modified electrode for detection of organophosphate pesticide. Talanta. https://doi.org/10.1016/j.talanta.2016.05.002.
Li, W., Chen, X., Xie, L., Liu, Z., & Xiong, X. (2019). Bioelectrochemical systems for groundwater remediation: The development trend and research front revealed by bibliometric analysis. Water (Switzerland), 11(8), 6–9. https://doi.org/10.3390/w11081532.
Litovitz, T. L., Klein-Schwartz, W., White, S., Cobaugh, D. J., Youniss, J., Omslaer, J. C., et al. (2001). 2000 Annual report of the American Association of Poison Control Centers toxic exposure surveillance system. American Journal of Emergency Medicine. https://doi.org/10.1053/ajem.2001.25272.
Liu, L. Y., He, K., Hites, R. A., & Salamova, A. (2016). Hair and nails as noninvasive biomarkers of human exposure to brominated and organophosphate flame retardants. Environmental Science and Technology. https://doi.org/10.1021/acs.est.5b05073.
Liu, X., Ji, K., & Choi, K. (2012). Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish. Aquatic Toxicology. https://doi.org/10.1016/j.aquatox.2012.02.019.
Liu, G., & Lin, Y. (2005). Electrochemical sensor for organophosphate pesticides and nerve agents using zirconia nanoparticles as selective sorbents. Analytical Chemistry. https://doi.org/10.1021/ac050791t.
Liu, G., & Lin, Y. (2006). Biosensor based on self-assembling acetylcholinesterase on carbon nanotubes for flow injection/amperometric detection of organophosphate pesticides and nerve agents. Analytical Chemistry. https://doi.org/10.1021/ac051559q.
Liu, L. Y., Salamova, A., He, K., & Hites, R. A. (2015). Analysis of polybrominated diphenyl ethers and emerging halogenated and organophosphate flame retardants in human hair and nails. Journal of Chromatography A. https://doi.org/10.1016/j.chroma.2015.06.003.
London, L., Bourne, D., Sayed, R., & Eastman, R. (2004). Guillain-Barre syndrome in a rural farming district in South Africa: A possible relationship to environmental organophosphate exposure. Archives of Environmental Health. https://doi.org/10.1080/00039890409603436.
Ma, Y., Jin, J., Li, P., Xu, M., Sun, Y., Wang, Y., et al. (2017). Organophosphate ester flame retardant concentrations and distributions in serum from inhabitants of Shandong, China, and changes between 2011 and 2015. Environmental Toxicology and Chemistry. https://doi.org/10.1002/etc.3554.
Mansour, S. A. (2004). Pesticide exposure—Egyptian scene. Toxicology. https://doi.org/10.1016/j.tox.2004.01.036.
Marks, A. R., Harley, K., Bradman, A., Kogut, K., Barr, D. B., Johnson, C., et al. (2010). Organophosphate pesticide exposure and attention in young Mexican-American children: The CHAMACOS study. Environmental Health Perspectives. https://doi.org/10.1289/ehp.1002056.
Meeker, J. D., Cooper, E. M., Stapleton, H. M., & Hauser, R. (2013). Urinary metabolites of organophosphate flame retardants: Temporal variability and correlations with house dust concentrations. Environmental Health Perspectives. https://doi.org/10.1289/ehp.1205907.
Meeker, J. D., & Stapleton, H. M. (2010). House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parameters. Environmental Health Perspectives. https://doi.org/10.1289/ehp.0901332.
Mishra, R. K., Dominguez, R. B., Bhand, S., Muñoz, R., & Marty, J. L. (2012). A novel automated flow-based biosensor for the determination of organophosphate pesticides in milk. Biosensors & Bioelectronics. https://doi.org/10.1016/j.bios.2011.11.028.
Montoya, F. G., Alcayde, A., Baños, R., & Manzano-Agugliaro, F. (2018). A fast method for identifying worldwide scientific collaborations using the Scopus database. Telematics and Informatics. https://doi.org/10.1016/j.tele.2017.10.010.
Mulchandani, A., Chen, W., Mulchandani, P., Wang, J., & Rogers, K. R. (2001). Biosensors for direct determination of organophosphate pesticides. Biosensors & Bioelectronics. https://doi.org/10.1016/s0956-5663(01)00126-9.
Muñoz-Quezada, M. T., Lucero, B., Achú, E., Cornejo, C., Grillo, A., Iglesias, V., et al. (2016). Organophosphate pesticides and neuropsychological and motor effects in the Maule Region, Chile. Gaceta Sanitaria. https://doi.org/10.1016/j.gaceta.2016.01.006.
Musilek, K., Dolezal, M., Gunn-Moore, F., & Kuca, K. (2011). Design, evaluation and structure-Activity relationship studies of the AChE reactivators against organophosphorus pesticides. Medicinal Research Reviews. https://doi.org/10.1002/med.20192.
Norkaew, S., Lertmaharit, S., Wilaiwan, W., Siriwong, W., Pérez, H. M., & Robson, M. G. (2015). An association between organophosphate pesticides exposure and Parkinsonism amongst people in an agricultural area in Ubon Ratchathani Province. Thailand: Roczniki Państwowego Zakładu Higieny.
Noyes, P. D., Haggard, D. E., Gonnerman, G. D., & Tanguay, R. L. (2015). Advanced morphological-behavioral test platform reveals neurodevelopmental defects in embryonic zebrafish exposed to comprehensive suite of halogenated and organophosphate flame retardants. Toxicological Sciences. https://doi.org/10.1093/toxsci/kfv044.
Ojha, A., & Gupta, Y. K. (2017). Study of commonly used organophosphate pesticides that induced oxidative stress and apoptosis in peripheral blood lymphocytes of rats. Human and Experimental Toxicology. https://doi.org/10.1177/0960327116680273.
Ojha, A., & Srivastava, N. (2014). In vitro studies on organophosphate pesticides induced oxidative DNA damage in rat lymphocytes. Mutation Research-Genetic Toxicology and Environmental Mutagenesis. https://doi.org/10.1016/j.mrgentox.2014.01.007.
Ojha, A., Yaduvanshi, S. K., Pant, S. C., Lomash, V., & Srivastava, N. (2013). Evaluation of DNA damage and cytotoxicity induced by three commonly used organophosphate pesticides individually and in mixture, in rat tissues. Environmental Toxicology. https://doi.org/10.1002/tox.20748.
Okogbue, B. C., Ansa, E. J., & Seiyaboh, E. I. (2019). Toxicity study and the effect of organophosphate pesticide on the gill of Oreochromis niloticus (Linnaeus, 1758). Tropical Freshwater Biology. https://doi.org/10.4314/tfb.v27i2.7.
Olisah, C., Adeniji, A. O., Okoh, O. O., & Okoh, A. I. (2019a). Occurrence and risk evaluation of organochlorine contaminants in surface water along the course of Swartkops and Sundays River Estuaries, Eastern Cape Province, South Africa. Environmental Geochemistry and Health. https://doi.org/10.1007/s10653-019-00336-0.
Olisah, C., Okoh, O. O., & Okoh, A. I. (2018). A bibliometric analysis of investigations of polybrominated diphenyl ethers (PBDEs) in biological and environmental matrices from 1992–2018. Heliyon, 4(11), e00964. https://doi.org/10.1016/j.heliyon.2018.e00964.
Olisah, C., Okoh, O. O., & Okoh, A. I. (2019b). Global evolution of organochlorine pesticides research in biological and environmental matrices from 1992 to 2018: A bibliometric approach. Emerging Contaminants, 5, 157–167. https://doi.org/10.1016/j.emcon.2019.05.001.
Oliveri, A. N., Bailey, J. M., & Levin, E. D. (2015). Developmental exposure to organophosphate flame retardants causes behavioral effects in larval and adult zebrafish. Neurotoxicology and Teratology. https://doi.org/10.1016/j.ntt.2015.08.008.
Oliveri, A. N., Ortiz, E., & Levin, E. D. (2018). Developmental exposure to an organophosphate flame retardant alters later behavioral responses to dopamine antagonism in zebrafish larvae. Neurotoxicology and Teratology. https://doi.org/10.1016/j.ntt.2018.03.002.
Paul, K. C., Sinsheimer, J. S., Rhodes, S. L., Cockburn, M., Bronstein, J., & Ritz, B. (2016). Organophosphate pesticide exposures, nitric oxide synthase gene variants, and gene–pesticide interactions in a case–control study of parkinson’s disease, California (USA). Environmental Health Perspectives. https://doi.org/10.1289/ehp.1408976.
Pei, W., Peng, R., Gu, Y., Zhou, X., & Ruan, J. (2019). Research trends of acupuncture therapy on insomnia in two decades (from 1999 to 2018):a bibliometric analysis. BMC Complementary and Alternative Medicine, 19(1), 1–9. https://doi.org/10.1186/s12906-019-2606-5.
Persson, J., Wang, T., & Hagberg, J. (2018). Organophosphate flame retardants and plasticizers in indoor dust, air and window wipes in newly built low-energy preschools. Science of the Total Environment. https://doi.org/10.1016/j.scitotenv.2018.02.053.
Ramírez-Sánchez, K., & Alvarado-Hidalgo, F. (2018). Enzymatic inhibition constant of acetylcholinesterase for the electrochemical detection and sensing of Chlorpyrifos article history. Journal of Natural Resources and Development. https://doi.org/10.5027/jnrd.v8i0.02.
Ramírez-Santana, M., Zúñiga, L., Corral, S., Sandoval, R., Scheepers, P. T., Van Der Velden, K., et al. (2015). Assessing biomarkers and neuropsychological outcomes in rural populations exposed to organophosphate pesticides in Chile—Study design and protocol Environmental and occupational health. BMC Public Health. https://doi.org/10.1186/s12889-015-1463-5.
Rastogi, S. K., Tripathi, S., & Ravishanker, D. (2010). A study of neurologic symptoms on exposure to organophosphate pesticides in the children of agricultural workers. Indian Journal of Occupational and Environmental Medicine. https://doi.org/10.4103/0019-5278.72242.
Rauert, C., Schuster, J. K., Eng, A., & Harner, T. (2018). Global atmospheric concentrations of brominated and chlorinated flame retardants and organophosphate esters. Environmental Science and Technology. https://doi.org/10.1021/acs.est.7b06239.
Rauh, V. A., Perera, F. P., Horton, M. K., Whyatt, R. M., Bansal, R., Hao, X., et al. (2012). Brain anomalies in children exposed prenatally to a common organophosphate pesticide. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1203396109.
Razwiedani, L., & Rautenbach, P. (2017). Epidemiology of organophosphate poisoning in the Tshwane district of South Africa. Environmental Health Insights. https://doi.org/10.1177/1178630217694149.
Regnery, J., & Püttmann, W. (2010). Seasonal fluctuations of organophosphate concentrations in precipitation and storm water runoff. Chemosphere. https://doi.org/10.1016/j.chemosphere.2009.12.027.
Robb, E. L., & Baker, M. B. (2019). Organophosphate toxicity. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK470430/.
Romano, M. E., Hawley, N. L., Eliot, M., Calafat, A. M., Jayatilaka, N. K., Kelsey, K., et al. (2017). Variability and predictors of urinary concentrations of organophosphate flame retardant metabolites among pregnant women in Rhode Island. Environmental Health: A Global Access Science Source. https://doi.org/10.1186/s12940-017-0247-z.
Rosenstock, L., Keifer, M., Daniell, W. E., McConnell, R., & Claypoole, K. (1991). Chronic central nervous system effects of acute organophosphate pesticide intoxication. The Lancet. https://doi.org/10.1016/0140-6736(91)90356-t.
Sagiv, S. K., Bruno, J. L., Baker, J. M., Palzes, V., Kogut, K., Rauch, S., et al. (2019). Prenatal exposure to organophosphate pesticides and functional neuroimaging in adolescents living in proximity to pesticide application. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1903940116.
Sahub, C., Tuntulani, T., Nhujak, T., & Tomapatanaget, B. (2018). Effective biosensor based on graphene quantum dots via enzymatic reaction for directly photoluminescence detection of organophosphate pesticide. Sensors and Actuators, B: Chemical. https://doi.org/10.1016/j.snb.2017.11.072.
Sargent Jr, J. F. (2018). US research and development funding and performance: Fact sheet. Accessed Congressional Research Service. https://fas.org/sgp/crs/misc,44307.
Schang, G., Robaire, B., & Hales, B. F. (2016). Organophosphate flame retardants act as endocrine-disrupting chemicals in MA-10 mouse tumor Leydig cells. Toxicological Sciences. https://doi.org/10.1093/toxsci/kfw012.
Shadgan, B., Roig, M., HajGhanbari, B., & Reid, W. D. (2010). Top-cited articles in rehabilitation. Archives of Physical Medicine and Rehabilitation. https://doi.org/10.1016/j.apmr.2010.01.011.
Shoaib, N., Siddiqui, P. J. A., & Ali, A. (2012). Acute toxic effects of organophosphate pesticides on killifish fish (Aphanius dispar) juveniles. Pakistan Journal of Zoology, 44, 2.
Song, D., Li, Y., Lu, X., Sun, M., Liu, H., Yu, G., et al. (2017). Palladium-copper nanowires-based biosensor for the ultrasensitive detection of organophosphate pesticides. Analytica Chimica Acta. https://doi.org/10.1016/j.aca.2017.06.004.
Stapleton, H. M., Klosterhaus, S., Eagle, S., Fuh, J., Meeker, J. D., Blum, A., et al. (2009). Detection of organophosphate flame retardants in furniture foam and U.S. house dust. Environmental Science and Technology. https://doi.org/10.1021/es9014019.
Steenland, K., Jenkins, B., Ames, R. G., O’Malley, M., Chrislip, D., & Russo, J. (1994). Chronic neurological sequelae to organophosphate pesticide poisoning. American Journal of Public Health. https://doi.org/10.2105/ajph.84.5.731.
Strong, L. L., Thompson, B., Coronado, G. D., Griffith, W. C., Vigoren, E. M., & Islas, I. (2004). Health symptoms and exposure to organophosphate pesticides in farmworkers. American Journal of Industrial Medicine. https://doi.org/10.1002/ajim.20095.
Sun, X., Liu, B., & Xia, K. (2011). A sensitive and regenerable biosensor for organophosphate pesticide based on self-assembled multilayer film with CdTe as fluorescence probe. Luminescence. https://doi.org/10.1002/bio.1284.
Sun, L., Xu, W., Peng, T., Chen, H., Ren, L., Tan, H., et al. (2016). Developmental exposure of zebrafish larvae to organophosphate flame retardants causes neurotoxicity. Neurotoxicology and Teratology. https://doi.org/10.1016/j.ntt.2016.03.003.
Synnestvedt, M. B., Chen, C., & Holmes, J. H. (2005). CiteSpace II: Visualization and knowledge discovery in bibliographic databases. In AMIA annual symposium proceedings/AMIA symposium. AMIA symposium.
Tahim, A., Patel, K., Bridle, C., & Holmes, S. (2016). The 100 most cited articles in facial trauma: A bibliometric analysis. Journal of Oral and Maxillofacial Surgery. https://doi.org/10.1016/j.joms.2016.06.175.
Terry, A. V. (2012). Functional consequences of repeated organophosphate exposure: Potential non-cholinergic mechanisms. Pharmacology & Therapeutics. https://doi.org/10.1016/j.pharmthera.2012.03.001.
Timofeeva, O. A., Sanders, D., Seemann, K., Yang, L., Hermanson, D., Regenbogen, S., et al. (2008). Persistent behavioral alterations in rats neonatally exposed to low doses of the organophosphate pesticide, parathion. Brain Research Bulletin. https://doi.org/10.1016/j.brainresbull.2008.08.019.
United State Environmental Protection Agency (US EPA). (2019). Persistent organic pollutants: A global issue, A global response. Retrieved from https://www.epa.gov/international-cooperation/persistent-organic-pollutants-global-issue-global-response. Accessed 15 October 2019.
Van den Eede, N., Dirtu, A. C., Neels, H., & Covaci, A. (2011). Analytical developments and preliminary assessment of human exposure to organophosphate flame retardants from indoor dust. Environment International. https://doi.org/10.1016/j.envint.2010.11.010.
Van Emon, J. M. (2016). Immunoassay and other bioanalytical techniques. Boca Raton: CRC Press.
Van Noorden, R., Maher, B., & Nuzzo, R. (2014). The top 100 papers. Nature. https://doi.org/10.1038/514550a.
Waddell, B. L., Zahm, S. H., Baris, D., Weisenburger, D. D., Holmes, F., Burmeister, L. F., et al. (2001). Agricultural use of organophosphate pesticides and the risk of non-Hodgkin’s lymphoma among male farmers (United States). Cancer Causes and Control. https://doi.org/10.1023/a:1011293208949.
Wang, Q., Lam, J. C. W., Man, Y. C., Lai, N. L. S., Kwok, K. Y., Guo, Y. Y., et al. (2015a). Bioconcentration, metabolism and neurotoxicity of the organophorous flame retardant 1,3-dichloro 2-propyl phosphate (TDCPP) to zebrafish. Aquatic Toxicology. https://doi.org/10.1016/j.aquatox.2014.11.001.
Wang, R., Tang, J., Xie, Z., Mi, W., Chen, Y., Wolschke, H., et al. (2015b). Occurrence and spatial distribution of organophosphate ester flame retardants and plasticizers in 40 rivers draining into the Bohai Sea, north China. Environmental Pollution. https://doi.org/10.1016/j.envpol.2014.12.037.
Wang, Y., Zhai, X., Liu, C., Wang, N., & Wang, Y. (2016). Trends of triple negative breast cancer research (2007–2015): A bibliometric study. Medicine (United States). https://doi.org/10.1097/md.0000000000005427.
Wang, Y., Zhang, Y., Ji, L., Hu, Y., Zhang, J., Wang, C., et al. (2017). Prenatal and postnatal exposure to organophosphate pesticides and childhood neurodevelopment in Shandong, China. Environment International. https://doi.org/10.1016/j.envint.2017.08.010.
Wei, G. L., Li, D. Q., Zhuo, M. N., Liao, Y. S., Xie, Z. Y., Guo, T. L., et al. (2015). Organophosphorus flame retardants and plasticizers: Sources, occurrence, toxicity and human exposure. Environmental Pollution. https://doi.org/10.1016/j.envpol.2014.09.012.
WenJun, Z., FuBin, J., & Ou, J. (2011). Global pesticide consumption and pollution. IAEES, 1, 125–144.
Woskie, S., Kongtip, P., Thanasanpaiboon, W., Kiatdamrong, N., Charoonrungsirikul, N., Nankongnab, N., et al. (2017). A pilot study of maternal exposure to organophosphate pesticides and newborn neurodevelopment in Thailand. International Journal of Occupational and Environmental Health. https://doi.org/10.1080/10773525.2018.1450324.
Xie, C., Li, H., Li, S., Wu, J., & Zhang, Z. (2010). Surface molecular self-assembly for organophosphate pesticide imprinting in electropolymerized poly(p-aminothiophenol) membranes on a gold nanoparticle modified glassy carbon electrode. Analytical Chemistry. https://doi.org/10.1021/ac901860t.
Yang, J., Zhao, Y., Li, M., Du, M., Li, X., & Li, Y. (2019). A review of a class of emerging contaminants: The classification, distribution, intensity of consumption, synthesis routes, environmental effects and expectation of pollution abatement to organophosphate flame retardants (OPFRs). International Journal of Molecular Sciences. https://doi.org/10.3390/ijms20122874.
Young, J. G., Eskenazi, B., Gladstone, E. A., Bradman, A., Pedersen, L., Johnson, C., et al. (2005). Association between in utero organophosphate pesticide exposure and abnormal reflexes in neonates. Neurotoxicology. https://doi.org/10.1016/j.neuro.2004.10.004.
Zha, D., Li, Y., Yang, C., & Yao, C. (2018). Assessment of organophosphate flame retardants in surface water and sediment from a freshwater environment (Yangtze River, China). Environmental Monitoring and Assessment. https://doi.org/10.1007/s10661-018-6587-5.
Zhang, Y., Han, S., Liang, D., Shi, X., Wang, F., Liu, W., et al. (2014). Prenatal exposure to organophosphate pesticides and neurobehavioral development of neonates: A birth cohort study in Shenyang, China. PLoS ONE. https://doi.org/10.1371/journal.pone.0088491.
Zhang, B., Lu, S., Huang, M., Zhou, M., Zhou, Z., Zheng, H., et al. (2018). Urinary metabolites of organophosphate flame retardants in 0–5-year-old children: Potential exposure risk for inpatients and home-stay infants. Environmental Pollution. https://doi.org/10.1016/j.envpol.2018.08.051.
Zhao, F., Li, Y., Zhang, S., Ding, M., & Hu, J. (2019). Association of aryl organophosphate flame retardants triphenyl phosphate and 2-ethylhexyl diphenyl phosphate with human blood triglyceride and total cholesterol levels. Environmental Science & Technology Letters. https://doi.org/10.1021/acs.estlett.9b00417.
Zhou, L., Zhang, X., Ma, L., Gao, J., & Jiang, Y. (2017). Acetylcholinesterase/chitosan-transition metal carbides nanocomposites-based biosensor for the organophosphate pesticides detection. Biochemical Engineering Journal. https://doi.org/10.1016/j.bej.2017.10.008.
Zou, Y., Luo, Y., Zhang, J., Xia, N., Tan, G., & Huang, C. (2019). Bibliometric analysis of oncolytic virus research, 2000 to 2018. Medicine, 98(35), e16817. https://doi.org/10.1097/md.0000000000016817.
Acknowledgements
The authors were supported by DST/NRF Research Chair funding (Unique Grant Number 84375).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors wish to declare that there is no conflict of interest regarding the publication of this manuscript.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Electronic supplementary material
Below is the link to the electronic supplementary material.
Rights and permissions
About this article
Cite this article
Olisah, C., Adams, J.B. Systematic mapping of organophosphate contaminant (OPC) research trends between 1990 and 2018. Environ Geochem Health 42, 3481–3505 (2020). https://doi.org/10.1007/s10653-020-00594-3
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10653-020-00594-3