Vasculature has an essential role both in central nervous system health and diseases. A new optimized imaging and analysis pipeline helps to characterize blood vessel network topology and plasticity across large regions in detail.
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References
Kisler, K., Nelson, A. R., Montagne, A. & Zlokovic, B. V. Nat. Rev. Neurosci. (2017) https://doi.org/10.1038/nrn.2017.48.
Sweeney, M. D., Kisler, K., Montagne, A., Toga, A. W. & Zlokovic, B. V. Nat. Neurosci. 21, 1318–1331 (2018).
Iadecola, C. Neuron 96, 17–42 (2017).
Tsai, P. S. et al. J. Neurosci. 29, 14553–14570 (2009).
Wu, J. et al. NeuroImage 87, 199–208 (2014).
Hörl, D. et al. Nat. Methods 16, 870–874 (2019).
Bria, A. & Iannello, G. BMC Bioinformatics 13, 316 (2012).
Kirst, C. et al. Cell 180, 780–795.e25 (2020).
Vanlandewijck, M. et al. Nature 554, 475–480 (2018).
Zhang, H., Prabhakar, P., Sealock, R. & Faber, J. E. J. Cereb. Blood Flow Metab. 30, 923–934 (2010).
Montagne, A. et al. Blood-brain barrier breakdown in the aging human hippocampus. Neuron 85, 296–302 (2015).
Montagne, A. et al. Nat. Med. (2018) https://doi.org/10.1038/nm.4482.
Bell, R. D. et al. Neuron 68, 409–427 (2010).
Kisler, K. et al. Nat. Neurosci. 20, 406–416 (2017).
Kisler, K. et al. Front. Cell. Neurosci 14, 27 (2020).
Nikolakopoulou, A. M. et al. Nat. Neurosci. 22, 1089–1098 (2019).
Berthiaume, A.-A. et al. Cell Rep 22, 8–16 (2018).
Sagare, A. P., Sweeney, M. D., Makshanoff, J. & Zlokovic, B. V. Neurosci. Lett. 607, 97–101 (2015).
Zipfel, G. J., Han, H., Ford, A. L. & Lee, J.-M. Stroke 40, S16–19 (2009).
Thomas, T., Thomas, G., McLendon, C., Sutton, T. & Mullan, M. Nature 380, 168–171 (1996).
Iadecola, C. et al. Nat. Neurosci. 2, 157–161 (1999).
Faraco, G. et al. Nat. Neurosci. 21, 240–249 (2018).
Sweeney, M. D., Zhao, Z., Montagne, A., Nelson, A. R. & Zlokovic, B. V. Physiol. Rev. 99, 21–78 (2019).
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Kisler, K., Huuskonen, M.T. & Zlokovic, B.V. Building vascular roadmaps: A novel toolset for visualizing and annotating whole mouse brain vasculature. Lab Anim 49, 175–176 (2020). https://doi.org/10.1038/s41684-020-0556-7
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DOI: https://doi.org/10.1038/s41684-020-0556-7