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Leukemia-Like Cancer in Bivalves

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Abstract

The present review summarizes information available in the published literature on the distribution of disseminated neoplasia, or malignant leukemia (leukemia-like cancer), in populations of several bivalve species. This disease of marine Bivalvia has long been known; currently (with the development of molecular-genetic methods) its etiology is associated with retrotransposons that can be transmitted by horizontal gene transfer between different bivalve species. Transmission of retrotransposons, as well as neoplastic hemocytes or their clusters, is possible via seawater. The fact that the immune system of the recipient does not reject the neoplastic hemocytes is of particular interest. In some regions of the world, leukemia-like cancer causes serious economic damage to bivalve aquacultures. The development of methods to diagnose cancer in mollusks opens up broad prospects for their use in marine biology and can also be helpful in studying human malignant tumors.

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Funding

This study was supported by the Russian Science Foundation (project no. 19-74-20024).

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  1. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences, 690041, Vladivostok, Russia

    N. A. Odintsova

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  1. N. A. Odintsova
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Correspondence to N. A. Odintsova.

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The author declares that she has no conflict of interest. This article does not contain any studies involving animals or human participants performed by the author.

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Translated by E. Shvetsov

Invited paper published in connection with the 50th anniversary of the foundation of the Zhirmunsky Institute of Marine Biology (now Zhirmunsky NSCMB) FEB RAS.

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Odintsova, N.A. Leukemia-Like Cancer in Bivalves. Russ J Mar Biol 46, 59–67 (2020). https://doi.org/10.1134/S1063074020020078

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  • DOI: https://doi.org/10.1134/S1063074020020078

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