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Individual sensitivity of cold pressor, environmental meteorological factors associated with blood pressure and its fluctuation

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Abstract

Previous studies have examined the associations of meteorological factors with blood pressure; however, these associations have not fully elucidated, especially lacking of evidence from cohort study, little information about the associations of cold pressor sensitivity with blood pressure and its fluctuation. The objective of this study was to investigate the outdoor and indoor temperature, barometric pressure, humidity, and cold pressor sensitivity with blood pressure and its fluctuation. Forty-eight healthy subjects were recruited, and response of blood pressure to cold exposure was measured with cold pressor test (CPT). Then, all the subjects were followed up, and blood pressure was measured every half a month in a period of consecutive 12 months. Multiple panel analysis with random-effects generalized least squares (GLS) regression was used to analyze the effect of the outdoor and indoor temperature, barometric pressure, humidity, and response to cold pressor exposure on blood pressure. Outdoor and indoor temperature and humidity were found to be independently associated with blood pressure (all the P values < 0.05). The response to cold exposure positively associated with blood pressure and its fluctuation (P < 0.05). The subjects with higher cold pressor sensitivity had about 4.7 mmHg higher maximum difference of SBP in 1 year than the subjects with lower sensitivity. Outdoor and indoor temperature, humidity, and response to cold exposure are associated with blood pressure and its fluctuation. These findings provided extending evidence on blood pressure management in clinic and preventive practice.

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Funding

This work was supported by the grants from National Key Research and Development Program of China (2017YFC0907004) and Hangzhou Science and Technology Project (20171226Y27).

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Author notes

  1. Yaqin Ni and Qin Miao contributed equally to this work.

Authors and Affiliations

  1. Department of Infection Control, Sir Run Run Shaw Hospital Affiliated to School of Medicine, Zhejiang University, Hangzhou, 310020, Zhejiang, China

    Yaqin Ni

  2. Department of Epidemiology & Biostatistics, School of Public Health, Zhejiang University, Hangzhou, 310058, China

    Yaqin Ni, Ruizhi Zheng & Yimin Zhu

  3. Health Service Center of Wenxin Community, Xi-Hu District, Hangzhou, 310012, China

    Qin Miao

  4. Health Service Center of Xixi Community, Xi-Hu District, Hangzhou, 310012, China

    Ying Miao

  5. Affiliated Hangzhou Center of Disease Control and Prevention, Zhejiang University School of Public Health, Hangzhou Center for Disease Control and Prevention, Hangzhou, 310051, Zhejiang, China

    Xuhui Zhang

  6. Department of Respiratory Diseases, Sir Run Run Shaw Hospital Affiliated to School of Medicine, Zhejiang University, Hangzhou, 310020, Zhejiang, China

    Yimin Zhu

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  1. Yaqin Ni
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Correspondence to Xuhui Zhang or Yimin Zhu.

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Mean levels of SBP and DBP with meteorological factors by months in one year A. SBP and outdoor temperature. B. DBP and outdoor temperature. C. SBP and indoor temperature. D. DBP and indoor temperature. E. SBP and humidity. F. DBP and humidity. G. SBP and barometric pressure. H. DBP and barometric pressure (JPG 646 kb)

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Ni, Y., Miao, Q., Zheng, R. et al. Individual sensitivity of cold pressor, environmental meteorological factors associated with blood pressure and its fluctuation. Int J Biometeorol 64, 1509–1517 (2020). https://doi.org/10.1007/s00484-020-01928-7

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  • DOI: https://doi.org/10.1007/s00484-020-01928-7

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