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The Case of Myocardial Infarction in a Fifteen-Year-Old Adolescent Caused by Toxic Substances

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Abstract

The article reveals about the clinical accident of myocardial infarction in an adolescent after visiting a night club, where he had been drinking tequila. A "sniper" test was performed at home and showed synthetic marihuana in urine. The uniqueness of this case is the adolescent's difficult premorbid condition (severe diabetes mellitus type 1 and sub-compensated hypothyreosis) and the clinical course of the disease had caused difficulty in diagnosis which led to a belated hospitalization on the third day. Considering pain syndrome, infarction-like findings in ECG (ST elevation), high levels of cardiospecific enzymes (troponin elevated 70 times, aspartate aminotransferase—two times, creatine phosphokinase—4 times, lactate dehydrogenase and alkaline phosphatase—two times) and their slow tendency to normalize—a non-Q myocardial infarction diagnosis was performed. After complex treatment, the general condition of the patient improved; he was discharged from the clinic in satisfactory general condition and was given recommendations for further rehabilitation. Given the potential for premature death and long-term disability with the development of negative individual and social consequences, the correct diagnostic assessment in such cases becomes particularly relevant.

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Abbreviations

ALP:

Alkaline phosphatase

AST:

Aspartate aminotransferase

BP:

Blood pressure

CPK-MB:

Creatine phosphokinase-MB

DM:

Diabetes mellitus

ECG:

Electrocardiography

HbA1c:

Glycated hemoglobin

HDL:

High density lipoprotein

HR:

Hear rate

LDH:

Lactate dehydrogenase

LDL:

Low density lipoprotein

MI:

Myocardial infarction

T3 :

Triiodothyronine

TG:

Triglycerides

References

  1. Kovalenko, M. V., Kornatsky, M. V. (2018). Actual health problems and their minimization in the context of armed conflict in Ukraine. Кyiv. 214 p. (in Ukrainian).

  2. Fournier, J. A., Cabezón, S., Cayuela, A., Ballesteros, S. M., Cortacero, J. A., & Díaz De La Llera, L. S. (2004). Long-term prognosis of patients having acute myocardial infarction when %3c/= 40 years of age. American Journal of Cardiology, 94, 989–992.

    Article  PubMed  Google Scholar 

  3. Maslennykova, G.P. (2006). Prevalence of myocardium ischemia in children and adolescents. Vestnyk Orenburhskoho Hosudarstvennoho unyversyteta. Spets. Vypusk Nauka Tekhnolohyy Proyzvodstvo Rynok. 13(63):256 (in Russian).

  4. Lin, M. C., Lee, W. L., & Fu, Y. C. (2015). Successful percutaneous transluminal coronary angioplasty for acute myocardial infarction in a 12-year-old boy with fibromuscular dysplasia: A case report. Cardiology in the Young, 25(1), 177–180.

    Article  PubMed  Google Scholar 

  5. Papneja, K., Chan, A. K., Mondal, T. K., & Paes, B. (2017). Myocardial infarction in neonates: A review of an entity with significant morbidity and mortality. Pediatric Cardiology, 38(3), 427–441.

    Article  PubMed  Google Scholar 

  6. Perrier, S., Parker, A., Brizard, C. P., Sheridan, B., Konstantinov, I. E., d'Udekem, Y., et al. (2017). Surgical management of extensive perinatal myocardial infarction. Annals of Thoracic Surgery, 104(6), 435–437.

    Article  Google Scholar 

  7. Park, W. S., Jeong, M. H., Hong, Y. J., Park, O. Y., Kim, J. H., Kim, W., et al. (2003). A case of acute myocardial infarction after blunt chest trauma in a young man. Journal of Korean Medical Science., 18(6), 889–893.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Lane, J. R., & Ben-Shachar, G. (2007). Myocardial infarction in healthy adolescents. Pediatrics, 120(4), 938–943.

    Article  Google Scholar 

  9. Briassoulis, G., Kalabalikis, P., Thanopoulos, V., & Hatzis, T. (2000). Non-Q wave acute myocardial infarction in acute meningococcemia in a 10-year-old girl. Pediatric Emergency Care, 16(1), 33–38.

    Article  CAS  PubMed  Google Scholar 

  10. Foraker, R. E., Guha, A., Chang, H., O'Brien, E. C., Bower, J. K., Crouser, E. D., et al. (2018). Survival after MI in a community cohort study: Contribution of comorbidities in NSTEMI. Global Heart., 13(1), 13–18.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Fazila-Tun-Nesa, M., Kalimuddin, M., Ahmed, N., Badiuzzzaman, M., Ahmed, M. N., Dutta, A., et al. (2016). AMI in very young (aged ≤35years) Bangladeshi patients: Risk factors & coronary angiographic profile. Clinical Trials and Regulatory Science in Cardiology., 13, 1–5.

    Article  Google Scholar 

  12. Hill, D., Waldman, A., & Vivek, D. (2016). A 16-year-old with ST elevation myocardial infarction: Case report and review of the literature. Cardiology in the Young, 26(2), 230–236.

    Article  PubMed  Google Scholar 

  13. Franz, C. A., & Frishman, W. H. (2016). Marijuana use and cardiovascular disease. Cardiology Review, 24(4), 158–162.

    Article  Google Scholar 

  14. Brown, T. T., & Dobs, A. S. (2002). Endocrine effects of marijuana. Journal of Clinical Pharmacology, 42(S1), 90S–96S.

    Article  CAS  PubMed  Google Scholar 

  15. Porcella, A., Marchese, G., Casu, M. A., Rocchitta, A., Lai, M. L., Gessa, G. L., et al. (2002). Evidence for functional CB1 cannabinoid receptor expressed in the rat thyroid. European Journal of Endocrinology, 147(2), 255–261.

    Article  CAS  PubMed  Google Scholar 

  16. Rosenkrantz, H., & Esber, H. J. (1980). Cannabinoid-induced hormone changes in monkeys and rats. Journal of Toxicology and Environment Health, 6(2), 297–313.

    Article  CAS  Google Scholar 

  17. Akturk, H. K., Taylor, D. D., Camsari, U. M., Rewers, A., Kinney, G. L., & Shah, V. N. (2019). Association between cannabis use and risk for diabetic ketoacidosis in adults with type 1 diabetes. JAMA Internal Medicine, 179(1), 115–118.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Anesthesiology and Intensive Care Department, P. L. Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine

    O. Loskutov, Yu. Markov, O. Druzhyna, V. Kolesnykov & S. Maruniak

  2. State Institution “Heart Institute Ministry of Health of Ukraine”, Kyiv, Ukraine

    O. Loskutov, B. Todurov, O. Druzhyna, V. Kolesnykov & S. Maruniak

Authors
  1. O. Loskutov
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  2. Yu. Markov
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  3. B. Todurov
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  4. O. Druzhyna
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  5. V. Kolesnykov
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  6. S. Maruniak
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Correspondence to S. Maruniak.

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Loskutov, O., Markov, Y., Todurov, B. et al. The Case of Myocardial Infarction in a Fifteen-Year-Old Adolescent Caused by Toxic Substances. Cardiovasc Toxicol 20, 520–524 (2020). https://doi.org/10.1007/s12012-020-09575-5

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  • DOI: https://doi.org/10.1007/s12012-020-09575-5

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