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A study on calcium phosphate/barium titanate composites: phase characterization, piezoelectric property, and cytocompatibility

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Abstract

A series of hydroxyapatite/barium titanate (HA/BT) and tricalcium phosphate/barium titanate (TCP/BT) composites were prepared in various mixing ratios and sintered at temperatures between 500 and 1300 °C using the powder metallurgy method. Sintering was performed under different atmospheres to evaluate the effect of the atmosphere on the phase stability of the composites. BT phase showed slightly higher phase stability in TCP/BT composites than in HA/BT composites. BT with low concentration behaved as a stabilizer of α-TCP. A reaction between HA and BT occurred at about 900 °C yielding byproducts of CaTiO3 and Ba2TiO4, at the expense of both HA and BT phases. CaTiO3 and Ba2TiO4 phases associated with low BT concentrations were observed in the composites sintered at temperatures between 1100 and 1300 °C. The HA/BT composites having BT concentrations less than 95 wt.% did not show any measurable piezoelectric response. Composites with BT promoted osteoblast adhesion even better than pure HA and TCP.

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Funding

This project was funded by Istanbul Technical University, Research Project Department, Project #31605 and #31957.

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Authors and Affiliations

  1. Department of Mechanical Engineering, Kahramanmaras Sutcu Imam University, 46050, Onikisubat, Kahramanmaras, Turkey

    Beril Ozcelik

  2. Department of Mechanical Engineering, Istanbul Technical University, 34437, Istanbul, Turkey

    Celaletdin Ergun

  3. Department of Bioengineering, University of California at Riverside, 900 University Avenue, Riverside, CA, 92521, USA

    Huinan Liu

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  1. Beril Ozcelik
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  2. Celaletdin Ergun
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  3. Huinan Liu
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Correspondence to Celaletdin Ergun.

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Ozcelik, B., Ergun, C. & Liu, H. A study on calcium phosphate/barium titanate composites: phase characterization, piezoelectric property, and cytocompatibility. J Aust Ceram Soc 56, 1197–1216 (2020). https://doi.org/10.1007/s41779-020-00468-y

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