Abstract
Tsukamurella spp. are gram-positive rods that can be isolated from the environment in soil and moist areas. In rare instances, they are known to cause infections in immunocompromised hosts. We present the first reported case of Tsukamurella endocarditis in an immunocompromised patient who was successfully treated with a 6-week course of imipenem and trimethoprim-sulfamethoxazole.
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References
World Health Organization (2017) Guidelines for drinking-water quality: fourth edition incorporating the first addendum. World Health Organization, Geneva
Safaei S, Fatahi-Bafghi M, Pouresmaeil O (2018) Role of Tsukamurella species in human infections: first literature review. New Microbes New Infect 22:6–12. https://doi.org/10.1016/j.nmni.2017.10.002
Schwartz MA, Tabet SR, Collier AC, Wallis CK, Carlson LC, Nguyen TT, Kattar MM, Coyle MB (2002) Central venous catheter-related bacteremia due to Tsukamurella species in the immunocompromised host: a case series and review of the literature. Clin Infect Dis 35:e72–e77. https://doi.org/10.1086/342561
Shim HE, Sung H, Baek SM et al (2009) A case of catheter-related bacteremia of Tsukamurella pulmonis. Korean J Lab Med 29(1):41–47. https://doi.org/10.3343/kjlm.2009.29.1.41
Suzuki J, Sasahara T, Toshima M et al (2017) Peripherally inserted central catheter-related bloodstream infection due to Tsukamurella pulmonis: a case report and literature review. BMC Infect Dis 17(1):677. https://doi.org/10.1186/s12879-017-2796-8
Takebe I, Sawabe E, Ohkusu K et al (2014) Catheter-related bloodstream infection by Tsukamurella inchonensis in an immunocompromised patient. J Clin Microbiol 52(6):2251–2253. https://doi.org/10.1128/JCM.00421-14
Lai KK (1993) A cancer patient with central venous catheter-related sepsis caused by Tsukamurella paurometabolum (Gordona aurantiaca). Clin Infect Dis 17(2):285–287. https://doi.org/10.1093/clinids/17.2.285-a
Long SS, Pickering LK, Prober CG (2012) Principles and practice of pediatric infectious disease. Elsevier/Saunders, Amsterdam
Bharadwaj R, Swaminathan S, Salimnia H, Fairfax M, Frey A, Chandrasekar PH (2012) Clinical impact of the use of 16S rRNA sequencing method for the identification of “difficult-to-identify” bacteria in immunocompromised hosts. Transpl Infect Dis 14:206–212. https://doi.org/10.1111/j.1399-3062.2011.00687.x
Maertens J, Wattiau P, Verhaegen J, Boogaerts M, Verbist L, Wauters G (1998) Catheter-related bacteremia due to Tsukamurella pulmonis. Clin Microbiol Infect 4:51–53. https://doi.org/10.1111/j.1469-0691.1998.tb00336.x
Karunakaran R, Halim HA, Ng KP et al (2011) Tsukamurella tyrosinosolvens intravascular catheter-related bacteremia in a haematology patient: a case report. Eur Rev Med Pharmacol Sci 15(11):1343–1346
Shapiro CL, Haft RF, Gantz NM, Doern GV, Christenson JC, O’Brien R et al (1992) Tsukamurella paurometabolum: a novel pathogen causing catheter-related bacteremia in patients with cancer. Clin Infect Dis 14(1):200–203
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Malik, Z., Shah, P.J. & Tariq, F. First report of Tsukamurella endocarditis in an immunocompromised patient receiving chemotherapy. Eur J Clin Microbiol Infect Dis 39, 1989–1991 (2020). https://doi.org/10.1007/s10096-020-03917-5
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DOI: https://doi.org/10.1007/s10096-020-03917-5