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Nanoscale Correlation Analysis of the Morphological, Optical, and Magnetic Structure of Polymer Microspheres for Multiplex Diagnostics

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Abstract

A unified analytical technology based on the integration of scanning probe nanotomography and optical microscopy (SPNT–OM) is presented, and the potential of the technology is demonstrated by the example of a multiparameter analysis of encoded microspheres. The presented SPNT–OM technology can become a powerful tool for multimodal nanocharacterization of a wide range of microparticles, composites, and hybrid polymers.

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Funding

This work was supported by the Russian Science Foundation, project no. 18-19-00718.

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Authors and Affiliations

  1. Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290, Moscow, Russia

    K. E. Mochalov, A. N. Generalova, I. S. Vaskan, D. O. Solov’eva & V. A. Oleinikov

  2. Academician Shumakov National Medical Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation, 123182, Moscow, Russia

    O. I. Agapova, I. I. Agapov & A. E. Efimov

  3. Moscow Institute of Physics and Technology (National Research University), 141701, Dolgoprudnyi, Moscow oblast, Russia

    I. S. Vaskan

  4. Snotra LLC., 121205, Moscow, Russia

    A. E. Efimov

Authors
  1. K. E. Mochalov
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  2. O. I. Agapova
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  3. A. N. Generalova
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  4. I. S. Vaskan
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  5. D. O. Solov’eva
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  6. V. A. Oleinikov
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  7. I. I. Agapov
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  8. A. E. Efimov
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Corresponding author

Correspondence to A. E. Efimov.

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The authors declare that they have no conflict of interest.

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Translated by O. Zhukova

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Mochalov, K.E., Agapova, O.I., Generalova, A.N. et al. Nanoscale Correlation Analysis of the Morphological, Optical, and Magnetic Structure of Polymer Microspheres for Multiplex Diagnostics. Tech. Phys. Lett. 46, 224–227 (2020). https://doi.org/10.1134/S1063785020030128

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  • DOI: https://doi.org/10.1134/S1063785020030128

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