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Preparation and Characterization of PLA Film/3D Printing Composite Scaffold for Tissue Engineering Application

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Abstract

Three-dimensional (3D) printing technology provides an effective alternative for tissue engineering scaffold. In this paper, a composite scaffold composed of polylactic acid (PLA) film and 3D printing scaffold was fabricated which could provide structural and mechanical support for tissue application. The effects of PLA film/3D printing composite scaffold on scaffold morphology, average diameter, pore diameter, mechanical properties, themal conductivity, electrical conductivity, and surface hydrophilicity were characterized. PLA film/3D printing composite scaffold had larger thickness, better mechanical and thermal conductivity properties in comparison with pure PLA film and 3D printed scaffold. These results suggested that composite scaffold with relatively good overall performance could be a potential candidate for tissue engineering application.

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Acknowledgement

This project was financially supported by Zhejiang Sci-Tech University Scientific Research Project (No.16012055-Y), Key Laboratory of Advanced Textile Materials and Manufacturing Technology (Zhejiang Sci-Tech University), Ministry of Education (No.2016QN06), Zhejiang Sci-Tech University (Engineering Research Center of Clothing of Zhejiang Province) (No.2018FZKF07) and The Open Project Program of Key Laboratory of Eco-textiles, Ministry of Education, Jiangnan University (No. KLET1711), Fujian Key Laboratory of Novel Functional Textile Fibers and Materials, Minjiang University (No. FKLTFM1817), State Key Laboratory of Molecular Engineering of Polymers, Fudan University (No. K2019-04).

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Correspondence to Wenbin Jiang or Jianyong Feng.

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Meng, C., Zhao, J., Yin, Y. et al. Preparation and Characterization of PLA Film/3D Printing Composite Scaffold for Tissue Engineering Application. Fibers Polym 21, 709–716 (2020). https://doi.org/10.1007/s12221-020-9305-1

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  • DOI: https://doi.org/10.1007/s12221-020-9305-1

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