The Microbiome Sets the Stage for Cholera

doi:10.1016/j.tim.2020.03.002

Trends in Microbiology

Volume 28, Issue 6, June 2020, Pages 430-432

https://doi.org/10.1016/j.tim.2020.03.002 Get rights and content

Interactions between the eukaryotic host, microbiome members, and invading pathogens help to shape disease outcomes. Using the Drosophila model, Fast et al. identified that Vibrio cholerae acts to inhibit epithelial renewal through complex interactions between the type VI secretion system of V. cholerae and the microbial community of the fly.

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Cited by (1)

Dksa coordinates bile-mediated regulation of virulence-associated phenotypes in type three secretion system-positive vibrio cholerae
2021, Microbiology (United Kingdom)

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Trends in Microbiology

References (19)

Effects of vaginal lactobacilli in Chlamydia trachomatis infection

Int. J. Med. Microbiol.

Cholera toxin disrupts barrier function by inhibiting exocyst-mediated trafficking of host proteins to intestinal cell junctions

Cell Host Microbe

A view to a kill: the bacterial type VI secretion system

Cell Host Microbe

Translocation of a Vibrio cholerae type VI secretion effector requires bacterial endocytosis by host cells

Cell Host Microbe

Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

Nat. Commun.

Decreased diversity of the fecal microbiome in recurrent Clostridium difficile-associated diarrhea

J. Infect. Dis.

The interplay between microbiome dynamics and pathogen dynamics in a murine model of Clostridium difficile infection

Gut Microbes

Bacterial vaginosis assessed by gram stain and diminished colonization resistance to incident gonococcal, chlamydial, and trichomonal genital infection

J. Infect. Dis.

Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication

Mol. Microbiol.

Cited by (1)

Dksa coordinates bile-mediated regulation of virulence-associated phenotypes in type three secretion system-positive vibrio cholerae

Trends in Microbiology

SpotlightThe Microbiome Sets the Stage for Cholera

Int. J. Med. Microbiol.

Cell Host Microbe

Cell Host Microbe

Cell Host Microbe

Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

Nat. Commun.

Decreased diversity of the fecal microbiome in recurrent Clostridium difficile-associated diarrhea

J. Infect. Dis.

The interplay between microbiome dynamics and pathogen dynamics in a murine model of Clostridium difficile infection

Gut Microbes

Bacterial vaginosis assessed by gram stain and diminished colonization resistance to incident gonococcal, chlamydial, and trichomonal genital infection

J. Infect. Dis.

Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication

Mol. Microbiol.

Spotlight
The Microbiome Sets the Stage for Cholera