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A new route for developing highly efficient nano biochemical sensors for detecting ultra-low concentrations of tetracycline antibiotic residue in water

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Abstract

This study reports a new detection process for sensing ultra-low concentrations of tetracycline (TC), using a hot spot surface-enhanced Raman scattering (SERS) sensor. A gold nanoparticles/ macroporous silicon (Au NPs/macroPSi) hot spot SERS sensor was fabricated using a very simple and low cost method. The SERS signal was investigated using Au NPs/macroPSi hot spot SERS sensor for efficient detection of TC antibiotics at lower concentrations of (10−3–10−9) mol/L. The sensor showed an excellent performance for TC detection with an enhancement factor (EF) of 2 × 108, ultra-low detection limit of 10−9 mol/L, and very high reproducibility with a relative standard deviation of 2%. The effect of the pH value on the behavior of the SERS spectra for TC antibiotic was evaluated, and it was found that pH values of 5 and 6 were the best for the detection process of TC antibiotic.

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Acknowledgments

The authors would like to thank University of Technology, Baghdad-Iraq and Mustansiriyah University (www.uomustansiriyah.edu.iq), Baghdad-Iraq for their support in the present work.

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Authors and Affiliations

  1. Department of Applied Sciences, University of Technology, Baghdad, Iraq

    Alwan M. Alwan

  2. Department of Science, College of Basic Education, Mustansiriyah University, Baghdad, Iraq

    Layla A. Wali & Khulood K. Hasan

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  1. Alwan M. Alwan
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  2. Layla A. Wali
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Correspondence to Alwan M. Alwan.

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Alwan, A.M., Wali, L.A. & Hasan, K.K. A new route for developing highly efficient nano biochemical sensors for detecting ultra-low concentrations of tetracycline antibiotic residue in water. Gold Bull 53, 39–46 (2020). https://doi.org/10.1007/s13404-020-00272-3

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  • DOI: https://doi.org/10.1007/s13404-020-00272-3

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