Research ArticleTolerability and pharmacokinetics of ginsenosides Rb1, Rb2, Rc, Rd, and compound K after single or multiple administration of red ginseng extract in human beings
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Keywords
ginsenosides
pharmacokinetics
red ginseng
single and repeated administration
tolerability
Abbreviations
Hank's balanced salt solution
HBSS
apical to basal
A to B
basal to apical
B to A
apparent permeability
Papp
multiple reaction monitoring
MRM
liquid chromatography-tandem mass spectrometry
LC-MS/MS
area under the plasma concentration-time curve
AUC
maximum plasma concentration
Cmax
time to reach Cmax
Tmax
t1/2
elimination half-life
MRT
mean residence time
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© 2018 The Korean Society of Ginseng, Published by Elsevier Korea LLC.