Cell Metabolism
Volume 31, Issue 4, 7 April 2020, Pages 660-662
Journal home page for Cell Metabolism

Preview
NADH Ties One-Carbon Metabolism to Cellular Respiration

https://doi.org/10.1016/j.cmet.2020.03.012Get rights and content
Under an Elsevier user license
open archive

In this issue of Cell Metabolism, Yang et al., 2020 report that serine is a source of mitochondrial NADH derived from one-carbon metabolism. Serine becomes a major source of NADH when cellular respiration is inhibited, and the un-utilized, accumulated NADH inhibits the TCA cycle and slows proliferation.

Cited by (0)