Journal of Molecular Biology
X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking
Graphical abstract
Section snippets
Accession codes
Coordinates have been deposited to the PDB with IDs 6XTE (isoform-1) and 6XU2 (isoform-3).
Acknowledgments
We thank all members of our laboratories for their contributions and helpful discussions. C.S. was funded by the Hofmann-La Roche pRED external collaboration programme. This work was supported by the Agence Nationale pour la Recherche (ANR-14-CE09-0017, RNAP-IAV) and the European Commission (EC) framework program 7 project ComplexINC (contract no. 279039). This study used the platforms of the Grenoble Instruct Centre (ISBG; UMS 3518 CNRS-CEA-UJF-EMBL) with support from FRISBI (ANR-10-INSB-05-02
Declaration of Competing Interests
The authors declare no conflicts of interest.
Author contributions
Conceptualization: T.C.; Methodology: T.C., B.D. and C.B.; Investigation: C.S., B.D.C., L.S., F.G., A.A.M.C. and T.C.; Writing - Original Draft: C.S. and T.C.; Writing - Review & Editing: T.C., C.S., B.D., C.B., I.B. and R.W.H.R.; Supervision: T.C., B.D., C.B., I.B. and R.W.H.R.; Funding Acquisition: T.C., B.D., C.B., I.B. and R.W.H.R.
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Present address: C. Swale, Institute for Advanced Biosciences (IAB), INSERM U1209, CNRS UMR 5309, University Grenoble Alpes, 38000 Grenoble, France.
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Present address: F. Garzoni, Imophoron Ltd., UnitDX, St. Philips Central, Albert Road, Bristol BS2 OXJ, United Kingdom.